| Design and computational analysis of single-cell RNA-sequencing experiments R Bacher, C Kendziorski Genome biology 17, 1-14, 2016 | 535 | 2016 |
| SCnorm: robust normalization of single-cell RNA-seq data R Bacher, LF Chu, N Leng, AP Gasch, JA Thomson, RM Stewart, ... Nature methods 14 (6), 584-586, 2017 | 298 | 2017 |
| Single-cell RNA sequencing reveals intrinsic and extrinsic regulatory heterogeneity in yeast responding to stress AP Gasch, FB Yu, J Hose, LE Escalante, M Place, R Bacher, J Kanbar, ... PLoS biology 15 (12), e2004050, 2017 | 143* | 2017 |
| An in vitro human segmentation clock model derived from embryonic stem cells LF Chu, D Mamott, Z Ni, R Bacher, C Liu, S Swanson, C Kendziorski, ... Cell reports 28 (9), 2247-2255. e5, 2019 | 57 | 2019 |
| Genetic drivers of pancreatic islet function MP Keller, DM Gatti, KL Schueler, ME Rabaglia, DS Stapleton, P Simecek, ... Genetics 209 (1), 335-356, 2018 | 55 | 2018 |
| Species-specific developmental timing is maintained by pluripotent stem cells ex utero C Barry, MT Schmitz, P Jiang, MP Schwartz, BM Duffin, S Swanson, ... Developmental biology 423 (2), 101-110, 2017 | 51 | 2017 |
| CD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cells MC Kim, N Borcherding, KK Ahmed, AP Voigt, A Vishwakarma, R Kolb, ... Nature communications 12 (1), 5764, 2021 | 45 | 2021 |
| Insulin-like growth factor dysregulation both preceding and following type 1 diabetes diagnosis MR Shapiro, CH Wasserfall, SM McGrail, AL Posgai, R Bacher, A Muir, ... Diabetes 69 (3), 413-423, 2020 | 41 | 2020 |
| Single-cell RNA-seq of human myeloid-derived suppressor cells in late sepsis reveals multiple subsets with unique transcriptional responses: a pilot study DB Darden, R Bacher, MA Brusko, P Knight, RB Hawkins, MC Cox, ... Shock 55 (5), 587-595, 2021 | 38 | 2021 |
| Human regulatory T cells from umbilical cord blood display increased repertoire diversity and lineage stability relative to adult peripheral blood K Motwani, LD Peters, WH Vliegen, AG El-Sayed, HR Seay, MC Lopez, ... Frontiers in immunology 11, 611, 2020 | 32 | 2020 |
| Trendy: segmented regression analysis of expression dynamics in high-throughput ordered profiling experiments R Bacher, N Leng, LF Chu, Z Ni, JA Thomson, C Kendziorski, R Stewart BMC bioinformatics 19, 1-10, 2018 | 29 | 2018 |
| Exocrine pancreatic enzymes are a serological biomarker for type 1 diabetes staging and pancreas size JJ Ross, CH Wasserfall, R Bacher, DJ Perry, K McGrail, AL Posgai, ... Diabetes 70 (4), 944-954, 2021 | 24 | 2021 |
| Overlapping but disparate inflammatory and immunosuppressive responses to SARS-CoV-2 and bacterial sepsis: An immunological time course analysis TJ Loftus, R Ungaro, M Dirain, PA Efron, MB Mazer, KE Remy, ... Frontiers in immunology 12, 792448, 2021 | 23 | 2021 |
| A novel single cell RNA-seq analysis of non-myeloid circulating cells in late sepsis DB Darden, X Dong, MA Brusko, L Kelly, B Fenner, JC Rincon, ML Dirain, ... Frontiers in Immunology 12, 696536, 2021 | 22 | 2021 |
| TCR+/BCR+ dual-expressing cells and their associated public BCR clonotype are not enriched in type 1 diabetes AS Japp, W Meng, AM Rosenfeld, DJ Perry, P Thirawatananond, ... Cell 184 (3), 827-839. e14, 2021 | 19 | 2021 |
| Identification of direct transcriptional targets of NFATC2 that promote β cell proliferation SP Simonett, S Shin, JA Herring, R Bacher, LA Smith, C Dong, ... The Journal of clinical investigation 131 (21), 2021 | 16 | 2021 |
| Normalization by distributional resampling of high throughput single-cell RNA-sequencing data J Brown, Z Ni, C Mohanty, R Bacher, C Kendziorski Bioinformatics 37 (22), 4123-4128, 2021 | 15 | 2021 |
| Automated minute scale RNA-seq of pluripotent stem cell differentiation reveals early divergence of human and mouse gene expression kinetics C Barry, MT Schmitz, C Argus, JM Bolin, MD Probasco, N Leng, BM Duffin, ... PLOS Computational Biology 15 (12), e1007543, 2019 | 13 | 2019 |
| Genetic composition and autoantibody titers model the probability of detecting C-peptide following type 1 diabetes diagnosis MKD Williams, R Bacher, DJ Perry, CR Grace, KM McGrail, AL Posgai, ... Diabetes 70 (4), 932-943, 2021 | 11 | 2021 |
| Evaluation of a multivalent transcriptomic metric for diagnosing surgical sepsis and estimating mortality among critically ill patients SC Brakenridge, UI Chen, T Loftus, R Ungaro, M Dirain, A Kerr, L Zhong, ... JAMA Network Open 5 (7), e2221520-e2221520, 2022 | 10 | 2022 |
