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Matthew Rausch
Matthew Rausch
Surface Oncology
Verified email at surfaceoncology.com
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Cited by
Year
PI3Kγ is a molecular switch that controls immune suppression
MM Kaneda, KS Messer, N Ralainirina, H Li, CJ Leem, S Gorjestani, ...
Nature 539 (7629), 437-442, 2016
10272016
Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells
O De Henau, M Rausch, D Winkler, LF Campesato, C Liu, DH Cymerman, ...
Nature 539 (7629), 443-447, 2016
7692016
Diverse cellular and organismal functions of the lysosomal thiol reductase GILT
MP Rausch, KT Hastings
Molecular immunology 68 (2), 124-128, 2015
772015
IL-27 and TCR stimulation promote T cell expression of multiple inhibitory receptors
JH DeLong, A O’Hara Hall, M Rausch, D Moodley, J Perry, J Park, ...
Immunohorizons 3 (1), 13-25, 2019
712019
Immune checkpoint inhibitors in the treatment of melanoma: from basic science to clinical application
MP Rausch, KT Hastings
Exon Publications, 121-142, 2017
602017
GILT accelerates autoimmunity to the melanoma antigen tyrosinase-related protein 1
MP Rausch, KR Irvine, PA Antony, NP Restifo, P Cresswell, KT Hastings
The Journal of Immunology 185 (5), 2828-2835, 2010
572010
An orally active small molecule TGF-β receptor I antagonist inhibits the growth of metastatic murine breast cancer
MP Rausch, T Hahn, L Ramanathapuram, D Bradley-Dunlop, ...
Anticancer research 29 (6), 2099-2109, 2009
552009
Correction: corrigendum: PI3Kγ is a molecular switch that controls immune suppression
MM Kaneda, KS Messer, N Ralainirina, H Li, CJ Leem, S Gorjestani, ...
Nature 542 (7639), 124-124, 2017
382017
GILT modulates CD4+ T-cell tolerance to the melanocyte differentiation antigen tyrosinase-related protein 1
MP Rausch, KT Hastings
Journal of investigative dermatology 132 (1), 154-162, 2012
372012
A stressful microenvironment: opposing effects of the endoplasmic reticulum stress response in the suppression and enhancement of adaptive tumor immunity
MP Rausch, AR Sertil
International reviews of immunology 34 (2), 104-122, 2015
202015
IL27 signaling serves as an immunologic checkpoint for innate cytotoxic cells to promote hepatocellular carcinoma
T Aghayev, AM Mazitova, JR Fang, IO Peshkova, M Rausch, M Hung, ...
Cancer discovery 12 (8), 1960-1983, 2022
182022
An exhaustion-like phenotype constrains the activity of CD4+ T cells specific for a self and melanoma antigen
MP Rausch, KT Hastings
PloS one 10 (4), e0123332, 2015
182015
Increased IL-27 is associated with poor prognosis in renal cell carcinoma and supports use of SRF388, a first-in-class IL-27p28 blocking antibody, to counteract IL-27-mediated …
M Rausch, J Hua, D Moodley, KF White, KH Walsh, CE Miller, G Tan, ...
Cancer Research 80 (16_Supplement), 4550-4550, 2020
102020
MERTK-specific antibodies that have therapeutic antitumor activity in mice disrupt the integrity of the retinal pigmented epithelium in cynomolgus monkeys
KF White, M Rausch, J Hua, KH Walsh, CE Miller, CC Wells, D Moodley, ...
Cancer Research 79 (13_Supplement), 558-558, 2019
102019
GILT in thymic epithelial cells facilitates central CD4 T cell tolerance to a tissue-restricted, melanoma-associated self-antigen
MP Rausch, LR Meador, TC Metzger, H Li, S Qiu, MS Anderson, ...
The Journal of Immunology 204 (11), 2877-2886, 2020
82020
Innate and adaptive immune responses to cancer
KT Hastings, MP Rausch
Fundamentals of Cancer Prevention, 81-121, 2013
82013
Cutaneous melanoma
NH Matthews, WQ Li, AA Qureshi, MA Weinstock, E Cho, M Norval, ...
Etiology and Therapy, 2017, 2017
62017
Checkpoint blockade therapy is improved by altering the immune suppressive microenvironment with IPI-549, a potent and selective inhibitor of PI3K-gamma, in preclinical models
O De Henau, T Merghoub, D Winkler, S Sharma, M Pink, J Tchaicha, ...
Cancer Research 76 (14_Supplement), 554-554, 2016
52016
Abstract B029: The potent and selective phosphoinositide-3-kinase-gamma inhibitor, IPI-549, inhibits tumor growth in murine syngeneic solid tumor models through alterations in …
J Kutok, J Ali, E Brophy, A Castro, J DiNitto, C Evans, K Faia, S Goldstein, ...
Cancer Immunology Research 4 (1_Supplement), B029-B029, 2016
52016
SRF617 is a potent inhibitor of CD39 with immunomodulatory and antitumor properties
MC Warren, S Matissek, M Rausch, M Panduro, RJ Hall, A Dulak, ...
ImmunoHorizons 7 (5), 366-379, 2023
42023
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