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John Victor Napoleon
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Cyclin dependent kinase 9 inhibitors for cancer therapy: miniperspective
YA Sonawane, MA Taylor, JV Napoleon, S Rana, JI Contreras, ...
Journal of medicinal chemistry 59 (19), 8667-8684, 2016
1402016
N‐substituted 1, 2, 3‐triazolyl‐appended indole‐chalcone hybrids as potential DNA intercalators endowed with antioxidant and anticancer properties
B Aneja, R Arif, A Perwez, JV Napoleon, P Hasan, MMA Rizvi, A Azam, ...
ChemistrySelect 3 (9), 2638-2645, 2018
372018
Transition-metal-free one-pot tandem synthesis of 4-quinolone and 4H-thiochromen-4-one derivatives through sequential nucleophilic addition–elimination–SNAr reaction
D Wang, P Sun, P Jia, J Peng, Y Yue, C Chen
Synthesis 49 (18), 4309-4320, 2017
182017
FtsZ inhibition and redox modulation with one chemical scaffold: Potential use of dihydroquinolines against mycobacteria
S Duggirala, JV Napoleon, RP Nankar, VS Adeeba, MK Manheri, M Doble
European journal of medicinal chemistry 123, 557-567, 2016
172016
Repolarization of tumor-infiltrating myeloid cells for augmentation of CAR T cell therapies
W Luo, JV Napoleon, F Zhang, YG Lee, B Wang, KS Putt, PS Low
Frontiers in Immunology 13, 816761, 2022
142022
An Expeditious and Metal‐Free Synthetic Route towards Quinolones, Naphthyridones and Benzonaphthyridones
NJ Victor, KM Muraleedharan
Advanced Synthesis & Catalysis 356 (17), 3600-3614, 2014
142014
N-substituted 1, 2-dihydroquinolines as anticancer agents: Electronic control of redox stability, assessment of antiproliferative effects, and mechanistic insights
NJ Victor, R Sakthivel, KM Muraleedharan, D Karunagaran
ChemMedChem 8 (10), 1623-1628, 2013
122013
N‐Methylpyrrolidone Hydroperoxide/Cs2CO3 as an Excellent Reagent System for the Hydroxy‐Directed Diastereoselective Epoxidation of Electron‐Deficient …
NJ Victor, J Gana, KM Muraleedharan
Chemistry–A European Journal 21 (42), 14742-14747, 2015
112015
Structure activity relationship (SAR) study identifies a quinoxaline urea analog that modulates IKKβ phosphorylation for pancreatic cancer therapy
S Sagar, S Singh, JR Mallareddy, YA Sonawane, JV Napoleon, S Rana, ...
European journal of medicinal chemistry 222, 113579, 2021
92021
Small molecule binding to inhibitor of nuclear factor kappa-B kinase subunit beta in an ATP non-competitive manner
JV Napoleon, S Singh, S Rana, M Bendjennat, V Kumar, S Kizhake, ...
Chemical Communications 57 (38), 4678-4681, 2021
72021
Small-molecule IKKβ activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth
JV Napoleon, S Sagar, SP Kubica, L Boghean, S Kour, HM King, ...
Proceedings of the National Academy of Sciences 119 (18), e2115071119, 2022
62022
Rahisuddin; Abid, M. N-substituted 1, 2, 3-triazolyl-appended indole-chalcone hybrids as potential DNA intercalators endowed with antioxidant and anticancer properties
B Aneja, R Arif, A Perwez, JV Napoleon, P Hasan, MMA Rizvi, A Azam
ChemistrySelect 3, 2638-2645, 2018
62018
Direct Transformation of Baylis-Hillman Acetates into N-Substituted Quinolones through an SN2′→ SNAr→(Δ3, 4-Δ2, 3 Shift)→ Oxidation Sequence
JV Napoleon, MK Manheri
Synthesis 2011 (20), 3379-3388, 2011
62011
Efficient capture of circulating tumor cells with low molecular weight folate receptor-specific ligands
Y Hu, D Chen, JV Napoleon, M Srinivasarao, S Singhal, CA Savran, ...
Scientific Reports 12 (1), 8555, 2022
52022
Design, Synthesis, and Targeted Delivery of an Immune Stimulant that Selectively Reactivates Exhausted CAR T Cells
JV Napoleon, B Zhang, Q Luo, M Srinivasarao, PS Low
Angewandte Chemie International Edition, 2022
42022
Sensitive manipulation of CAR T cell activity using a chimeric endocytosing receptor
B Zhang, JV Napoleon, X Liu, Q Luo, M Srinivasarao, PS Low
Journal for Immunotherapy of Cancer 8 (2), 2020
42020
Rejuvenation of car t cell
PS Low, B Zhang, JV Napoleon
US Patent App. 17/266,509, 2021
32021
Biological evaluation of novel side chain containing CQTrICh-analogs as antimalarials and their development as PfCDPK1 kinase inhibitors
I Irfan, A Uddin, R Jain, A Gupta, S Gupta, JV Napoleon, A Hussain, ...
Heliyon 10 (3), 2024
22024
Targeted Rejuvenation of Exhausted Chimeric Antigen Receptor T Cells Regresses Refractory Solid Tumors
Q Luo, JV Napoleon, X Liu, B Zhang, S Zheng, PS Low
Molecular Cancer Research 20 (5), 823-833, 2022
22022
Multi-chelation approach towards natural product-like skeletons: one-pot access to a nitrogen-containing tetracyclic framework from AlaAla dipeptide
K Vellaisamy, JV Napoleon, R Venkatachalam, MK Manheri
Chemical Communications 46 (48), 9212-9214, 2010
22010
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