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Garrett W. Rhyasen
Garrett W. Rhyasen
Verified email at gsk.com - Homepage
Title
Cited by
Cited by
Year
Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome
GW Rhyasen, L Bolanos, J Fang, A Jerez, M Wunderlich, C Rigolino, ...
Cancer cell 24 (1), 90-104, 2013
2112013
IRAK signalling in cancer
GW Rhyasen, DT Starczynowski
British journal of cancer 112 (2), 232-237, 2015
1742015
AZD5153: a novel bivalent BET bromodomain inhibitor highly active against hematologic malignancies
GW Rhyasen, MM Hattersley, Y Yao, A Dulak, W Wang, P Petteruti, ...
Molecular cancer therapeutics 15 (11), 2563-2574, 2016
1452016
Cytotoxic effects of bortezomib in myelodysplastic syndrome/acute myeloid leukemia depend on autophagy-mediated lysosomal degradation of TRAF6 and repression of PSMA1
J Fang, G Rhyasen, L Bolanos, C Rasch, M Varney, M Wunderlich, ...
Blood, The Journal of the American Society of Hematology 120 (4), 858-867, 2012
1312012
Deregulation of microRNAs in myelodysplastic syndrome
GW Rhyasen, DT Starczynowski
Leukemia 26 (1), 13-22, 2012
992012
OKT3 prevents xenogeneic GVHD and allows reliable xenograft initiation from unfractionated human hematopoietic tissues
M Wunderlich, RA Brooks, R Panchal, GW Rhyasen, G Danet-Desnoyers, ...
Blood, The Journal of the American Society of Hematology 123 (24), e134-e144, 2014
732014
BRD4 amplification facilitates an oncogenic gene expression program in high-grade serous ovarian cancer and confers sensitivity to BET inhibitors
GW Rhyasen, Y Yao, J Zhang, A Dulak, L Castriotta, K Jacques, W Zhao, ...
PLoS One 13 (7), e0200826, 2018
502018
An MDS xenograft model utilizing a patient-derived cell line
GW Rhyasen, M Wunderlich, K Tohyama, G Garcia-Manero, JC Mulloy, ...
Leukemia 28 (5), 1142-1145, 2014
492014
Modeling de novo leukemogenesis from human cord blood with MN1 and NUP98HOXD13
S Imren, M Heuser, M Gasparetto, PA Beer, GL Norddahl, P Xiang, ...
Blood, The Journal of the American Society of Hematology 124 (24), 3608-3612, 2014
372014
Differential IRAK signaling in hematologic malignancies
GW Rhyasen, L Bolanos, DT Starczynowski
Experimental hematology 41 (12), 1005-1007, 2013
222013
Combination therapy for MDS
D Starczynowski, GW Rhyasen
US Patent 9,855,273, 2018
152018
TNFAIP3 plays a role in aging of the hematopoietic system
MA Smith, AE Culver-Cochran, ER Adelman, GW Rhyasen, A Ma, ...
Frontiers in immunology 11, 536442, 2020
132020
Combination therapy for MDS
D Starczynowski, GW Rhyasen
US Patent 9,168,257, 2015
132015
Combination therapy with a phosphoinositide 3-kinase inhibitor with a zinc binding moiety
A Fattaey, GW Rhyasen
US Patent App. 15/800,386, 2018
52018
The combination of venetoclax and CUDC-907 exhibits synergistic activity in venetoclax-refractory DLBCL
K Sun, R Atoyan, MA Borek, S Dellarocca, G Rhyasen, A Fattaey, DP Tuck
Blood 128 (22), 4184, 2016
42016
Inhibition of IRAK1 As a Novel Therapeutic Strategy in Acute Myeloid Leukemia and Myelodysplastic Syndrome
G Rhyasen, L Bolanos, J Fang, C Rigolino, A Cortelezzi, EN Oliva, ...
Blood, The Journal of the American Society of Hematology 118 (21), 612-612, 2011
22011
Substituted Imidazo [1, 2-a]-pyridines as IRAK 1/4 and FLT3 inhibitors
DT Starczynowski, CJ Thomas, G Rhyasen, K Melgar, MM Walker, ...
US Patent 11,542,261, 2023
12023
BRD4 amplification facilitates an oncogenic gene expression program in high-grade serous ovarian cancer
GW Rhyasen, Y Yao, A Dulak, L Castriotta, K Jacques, M Hattersley, ...
Cancer Research 76 (14_Supplement), 1971-1971, 2016
12016
Combination therapy for MDS
D STARCZYNOWSKI, GW Rhyasen
CA Patent App. 2,907,960 A, 2014
12014
Development and Characterization of a Novel Human Xenograft Model Using an MDS Patient-Derived Cell Line
G Rhyasen, M Wunderlich, JC Mulloy, DT Starczynowski
Blood 120 (21), 3814, 2012
12012
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