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Tomi Rantamäki
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The role of BDNF and its receptors in depression and antidepressant drug action: reactivation of developmental plasticity
E Castrén, T Rantamäki
Developmental neurobiology 70 (5), 289-297, 2010
10532010
Role of neurotrophic factors in depression
E Castrén, V Võikar, T Rantamäki
Current opinion in pharmacology 7 (1), 18-21, 2007
8702007
Pharmacologically diverse antidepressants rapidly activate brain-derived neurotrophic factor receptor TrkB and induce phospholipase-Cγ signaling pathways in mouse brain
T Rantamäki, P Hendolin, A Kankaanpää, J Mijatovic, P Piepponen, ...
Neuropsychopharmacology 32 (10), 2152-2162, 2007
3572007
Enhanced BDNF signaling is associated with an antidepressant-like behavioral response and changes in brain monoamines.
E Koponen, T Rantamäki, V Voikar, T Saarelainen, E MacDonald, ...
Cellular and molecular neurobiology 25 (6), 973-980, 2005
1642005
Role of brain-derived neurotrophic factor in the aetiology of depression: implications for pharmacological treatment
E Castrén, T Rantamäki
CNS drugs 24, 1-7, 2010
1502010
Antidepressant drugs transactivate TrkB neurotrophin receptors in the adult rodent brain independently of BDNF and monoamine transporter blockade
T Rantamäki, L Vesa, H Antila, A Di Lieto, P Tammela, A Schmitt, ...
PloS one 6 (6), e20567, 2011
1332011
The antidepressant-like effects of glutamatergic drugs ketamine and AMPA receptor potentiator LY 451646 are preserved in bdnf+/− heterozygous null mice
JSO Lindholm, H Autio, L Vesa, H Antila, L Lindemann, MC Hoener, ...
Neuropharmacology 62 (1), 391-397, 2012
1112012
Cholesterol loss enhances TrkB signaling in hippocampal neurons aging in vitro
MG Martin, S Perga, L Trovo, A Rasola, P Holm, T Rantamäki, T Harkany, ...
Molecular Biology of the Cell 19 (5), 2101-2112, 2008
1082008
Impaired TrkB receptor signaling contributes to memory impairment in APP/PS1 mice
S Kemppainen, T Rantamäki, A Jeronimo-Santos, G Lavasseur, H Autio, ...
Neurobiology of aging 33 (6), 1122. e23-1122. e39, 2012
992012
BDNF and TrkB in neuronal differentiation of Fmr1-knockout mouse
V Louhivuori, A Vicario, M Uutela, T Rantamäki, LM Louhivuori, E Castren, ...
Neurobiology of disease 41 (2), 469-480, 2011
962011
Neurotrophins in depression and antidepressant effects
E Castrén, T Rantamäki
Growth Factors and Psychiatric Disorders: Novartis Foundation Symposium 289 …, 2008
882008
Isoflurane produces antidepressant effects and induces TrkB signaling in rodents
H Antila, M Ryazantseva, D Popova, P Sipilä, R Guirado, S Kohtala, ...
Scientific reports 7 (1), 7811, 2017
832017
Modulation of BDNF cleavage by plasminogen-activator inhibitor-1 contributes to Alzheimer's neuropathology and cognitive deficits
G Gerenu, E Martisova, H Ferrero, M Carracedo, T Rantamäki, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (4), 991 …, 2017
802017
A role for BDNF/TrkB signaling in behavioral and physiological consequences of social defeat stress
M Razzoli, E Domenici, L Carboni, T Rantamaki, J Lindholm, E Castren, ...
Genes, Brain and Behavior 10 (4), 424-433, 2011
762011
Darkness reduces BDNF expression in the visual cortex and induces repressive chromatin remodeling at the BDNF gene in both hippocampus and visual cortex
NN Karpova, T Rantamäki, A Di Lieto, L Lindemann, MC Hoener, ...
Cellular and molecular neurobiology 30, 1117-1123, 2010
692010
Acetylcholinesterase inhibitors rapidly activate Trk neurotrophin receptors in the mouse hippocampus
H Autio, K Mätlik, T Rantamäki, L Lindemann, MC Hoener, M Chao, ...
Neuropharmacology 61 (8), 1291-1296, 2011
652011
VGF (TLQP-62)-induced neurogenesis targets early phase neural progenitor cells in the adult hippocampus and requires glutamate and BDNF signaling
S Thakker-Varia, J Behnke, D Doobin, V Dalal, K Thakkar, F Khadim, ...
Stem cell research 12 (3), 762-777, 2014
642014
Alterations in BDNF and phospho-CREB levels following chronic oral nicotine treatment and its withdrawal in dopaminergic brain areas of mice
T Kivinummi, K Kaste, T Rantamäki, E Castrén, L Ahtee
Neuroscience letters 491 (2), 108-112, 2011
642011
The impact of Bdnf gene deficiency to the memory impairment and brain pathology of APPswe/PS1dE9 mouse model of Alzheimer’s disease
T Rantamäki, S Kemppainen, H Autio, S Staven, H Koivisto, M Kojima, ...
PLoS One 8 (7), e68722, 2013
632013
The effects of acute and long-term lithium treatments on trkB neurotrophin receptor activation in the mouse hippocampus and anterior cingulate cortex
T Rantamäki, JEA Knuuttila, ME Hokkanen, E Castrén
Neuropharmacology 50 (4), 421-427, 2006
572006
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