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Yozen Hernandez
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A naturally inspired antibiotic to target multidrug-resistant pathogens
Z Wang, B Koirala, Y Hernandez, M Zimmerman, S Park, DS Perlin, ...
Nature 601 (7894), 606-611, 2022
1202022
Inter- and intra-specific pan-genomes of Borrelia burgdorferi sensu lato: genome stability and adaptive radiation
EF Mongodin, SR Casjens, JF Bruno, Y Xu, EF Drabek, DR Riley, ...
BMC genomics 14, 1-25, 2013
892013
Pervasive Recombination and Sympatric Genome Diversification Driven by Frequency-Dependent Selection in Borrelia burgdorferi, the Lyme Disease Bacterium
J Haven, LC Vargas, EF Mongodin, V Xue, Y Hernandez, P Pagan, ...
Genetics 189 (3), 951-966, 2011
792011
Bioinformatic prospecting and synthesis of a bifunctional lipopeptide antibiotic that evades resistance
Z Wang, B Koirala, Y Hernandez, M Zimmerman, SF Brady
Science 376 (6596), 991-996, 2022
522022
Fast, adaptive evolution at a bacterial host-resistance locus: the PFam54 gene array in Borrelia burgdorferi
E Wywial, J Haven, SR Casjens, YA Hernandez, S Singh, EF Mongodin, ...
Gene 445 (1-2), 26-37, 2009
512009
VNTRseek—a computational tool to detect tandem repeat variants in high-throughput sequencing data
Y Gelfand, Y Hernandez, J Loving, G Benson
Nucleic acids research 42 (14), 8884-8894, 2014
372014
BitPAl: a bit-parallel, general integer-scoring sequence alignment algorithm
J Loving, Y Hernandez, G Benson
Bioinformatics 30 (22), 3166-3173, 2014
342014
Identification of structurally diverse menaquinone-binding antibiotics with in vivo activity against multidrug-resistant pathogens
L Li, B Koirala, Y Hernandez, LW MacIntyre, MA Ternei, R Russo, ...
Nature microbiology 7 (1), 120-131, 2022
282022
Genome-wide characterization of human minisatellite VNTRs: population-specific alleles and gene expression differences
M Eslami Rasekh, Y Hernández, SD Drinan, JI Fuxman Bass, G Benson
Nucleic acids research 49 (8), 4308-4324, 2021
222021
Biosynthetic Interrogation of Soil Metagenomes Reveals Metamarin, an Uncommon Cyclomarin Congener with Activity against Mycobacterium tuberculosis
L Li, LW MacIntyre, T Ali, R Russo, B Koirala, Y Hernandez, SF Brady
Journal of natural products 84 (4), 1056-1066, 2021
212021
BpWrapper: BioPerl-based sequence and tree utilities for rapid prototyping of bioinformatics pipelines
Y Hernández, R Bernstein, P Pagan, L Vargas, W McCaig, G Ramrattan, ...
BMC bioinformatics 19, 1-7, 2018
172018
A bit-parallel, general integer-scoring sequence alignment algorithm
G Benson, Y Hernandez, J Loving
Combinatorial Pattern Matching: 24th Annual Symposium, CPM 2013, Bad …, 2013
172013
Lapcin, a potent dual topoisomerase I/II inhibitor discovered by soil metagenome guided total chemical synthesis
Z Wang, N Forelli, Y Hernandez, M Ternei, SF Brady
Nature Communications 13 (1), 842, 2022
102022
Linkage disequilibrium based genotype calling from low-coverage shotgun sequencing reads
J Duitama, J Kennedy, S Dinakar, Y Hernández, Y Wu, II Măndoiu
BMC bioinformatics 12, 1-11, 2011
102011
High-throughput retrieval of target sequences from complex clone libraries using CRISPRi
J Burian, VK Libis, YA Hernandez, L Guerrero-Porras, MA Ternei, ...
Nature Biotechnology 41 (5), 626-630, 2023
82023
Sleep-wake disorders in Alzheimer’s disease: further genetic analyses in relation to objective sleep measures
JA Yesavage, A Noda, A Heath, MW McNerney, BW Domingue, ...
International Psychogeriatrics, 1-7, 2019
62019
Discovery of Paenibacillaceae family Gram-negative-active cationic lipopeptide antibiotics using evolution-guided chemical synthesis
Z Wang, B Koirala, Y Hernandez, SF Brady
Organic letters 24 (27), 4943-4948, 2022
52022
A study of the variability of minisatellite tandem repeat loci in the human genome based on high-throughput sequencing data
Y Hernandez
Boston University, 2019
12019
Tapcin, an In Vivo Active Dual Topoisomerase I/II Inhibitor Discovered by Synthetic Bioinformatic Natural Product (Syn‐BNP)‐Coupled Metagenomics
Z Wang, A Kasper, M Takahashi, A Morales Amador, A Bhattacharjee, ...
Angewandte Chemie International Edition 63 (17), e202317187, 2024
2024
Tapcin, an In Vivo Active Dual Topoisomerase I/II Inhibitor Discovered by Synthetic Bioinformatic Natural Product (Syn-BNP)-Coupled Metagenomics
Z Wang, A Kasper, M Takahashi, A Morales Amador, A Bhattacharjee, ...
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2024
2024
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