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Omar F. Khan
Omar F. Khan
Professor and Canada Research Chair in Nucleic Acid Therapeutics, University of Toronto
Verified email at mit.edu - Homepage
Title
Cited by
Cited by
Year
In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight
JE Dahlman, C Barnes, OF Khan, A Thiriot, S Jhunjunwala, TE Shaw, ...
Nature nanotechnology 9 (8), 648-655, 2014
6542014
Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose
JS Chahal, OF Khan, CL Cooper, JS McPartlan, JK Tsosie, LD Tilley, ...
Proceedings of the National Academy of Sciences 113 (29), E4133-E4142, 2016
4012016
Proliferation and recruitment contribute to myocardial macrophage expansion in chronic heart failure
HB Sager, M Hulsmans, KJ Lavine, MB Moreira, T Heidt, G Courties, ...
Circulation research 119 (7), 853-864, 2016
3802016
Small RNA combination therapy for lung cancer
W Xue, JE Dahlman, T Tammela, OF Khan, S Sood, A Dave, W Cai, ...
Proceedings of the National Academy of Sciences 111 (34), E3553-E3561, 2014
2672014
A perspective on the clinical translation of scaffolds for tissue engineering
MJ Webber, OF Khan, SA Sydlik, BC Tang, R Langer
Annals of biomedical engineering 43, 641-656, 2015
2342015
RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction
HB Sager, P Dutta, JE Dahlman, M Hulsmans, G Courties, Y Sun, T Heidt, ...
Science translational medicine 8 (342), 342ra80-342ra80, 2016
1872016
An RNA nanoparticle vaccine against Zika virus elicits antibody and CD8+ T cell responses in a mouse model
JS Chahal, T Fang, AW Woodham, OF Khan, J Ling, DG Anderson, ...
Scientific reports 7 (1), 252, 2017
1552017
Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy
K Jung, T Heishi, OF Khan, PS Kowalski, J Incio, NN Rahbari, E Chung, ...
The Journal of clinical investigation 127 (8), 3039-3051, 2017
1482017
Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature
OF Khan, EW Zaia, S Jhunjhunwala, W Xue, W Cai, DS Yun, CM Barnes, ...
Nano letters 15 (5), 3008-3016, 2015
1312015
Genetic and hypoxic alterations of the micro RNA‐210‐ISCU 1/2 axis promote iron–sulfur deficiency and pulmonary hypertension
K White, Y Lu, S Annis, AE Hale, BN Chau, JE Dahlman, C Hemann, ...
EMBO molecular medicine 7 (6), 695-713, 2015
1282015
Multiplexed RNAi therapy against brain tumor-initiating cells via lipopolymeric nanoparticle infusion delays glioblastoma progression
D Yu, OF Khan, ML Suvà, B Dong, WK Panek, T Xiao, M Wu, Y Han, ...
Proceedings of the National Academy of Sciences 114 (30), E6147-E6156, 2017
1182017
Endothelialized biomaterials for tissue engineering applications in vivo
OF Khan, MV Sefton
Trends in biotechnology 29 (8), 379-387, 2011
952011
Endothelial siRNA delivery in nonhuman primates using ionizable low–molecular weight polymeric nanoparticles
OF Khan, PS Kowalski, JC Doloff, JK Tsosie, V Bakthavatchalu, CB Winn, ...
Science advances 4 (6), eaar8409, 2018
942018
Nanoparticle-encapsulated siRNAs for gene silencing in the haematopoietic stem-cell niche
M Krohn-Grimberghe, MJ Mitchell, MJ Schloss, OF Khan, G Courties, ...
Nature biomedical engineering 4 (11), 1076-1089, 2020
912020
Ionizable amphiphilic dendrimer‐based nanomaterials with alkyl‐chain‐substituted amines for tunable siRNA delivery to the liver endothelium in vivo
OF Khan, EW Zaia, H Yin, RL Bogorad, JM Pelet, MJ Webber, I Zhuang, ...
Angewandte Chemie International Edition 53 (52), 14397-14401, 2014
892014
Endothelial cell behaviour within a microfluidic mimic of the flow channels of a modular tissue engineered construct
OF Khan, MV Sefton
Biomedical microdevices 13, 69-87, 2011
782011
Endothelial miR-30c suppresses tumor growth via inhibition of TGF-β–induced Serpine1
JV McCann, L Xiao, DJ Kim, OF Khan, PS Kowalski, DG Anderson, ...
The Journal of clinical investigation 129 (4), 1654-1670, 2019
762019
Lipid-like nanomaterials for simultaneous gene expression and silencing in vivo
Y Dong, AA Eltoukhy, CA Alabi, OF Khan, O Veiseh, JR Dorkin, ...
Advanced healthcare materials 3 (9), 1392, 2014
692014
MicroRNA regulation of endothelial TREX1 reprograms the tumour microenvironment
RA Wilson, C Espinosa-Diez, N Kanner, N Chatterjee, R Ruhl, C Hipfinger, ...
Nature communications 7 (1), 13597, 2016
642016
Ex vivo cytosolic delivery of functional macromolecules to immune cells
A Sharei, R Trifonova, S Jhunjhunwala, GC Hartoularos, AT Eyerman, ...
PLoS One 10 (4), e0118803, 2015
602015
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