| Caspase 8 small interfering RNA prevents acute liver failure in mice L Zender, S Hütker, C Liedtke, HL Tillmann, S Zender, B Mundt, ... Proceedings of the National Academy of Sciences 100 (13), 7797-7802, 2003 | 522 | 2003 |
| Experimental liver fibrosis research: update on animal models, legal issues and translational aspects C Liedtke, T Luedde, T Sauerbruch, D Scholten, K Streetz, F Tacke, ... Fibrogenesis & tissue repair 6, 1-25, 2013 | 412 | 2013 |
| The carbon tetrachloride model in mice D Scholten, J Trebicka, C Liedtke, R Weiskirchen Laboratory animals 49 (1_suppl), 4-11, 2015 | 365 | 2015 |
| Diethylnitrosamine (DEN)-induced carcinogenic liver injury in mice R Tolba, T Kraus, C Liedtke, M Schwarz, R Weiskirchen Laboratory animals 49 (1_suppl), 59-69, 2015 | 284 | 2015 |
| TAK1 suppresses a NEMO-dependent but NF-κB-independent pathway to liver cancer K Bettermann, M Vucur, J Haybaeck, C Koppe, J Janssen, F Heymann, ... Cancer cell 17 (5), 481-496, 2010 | 258 | 2010 |
| Chemokine receptor CCR6-dependent accumulation of γδ T cells in injured liver restricts hepatic inflammation and fibrosis L Hammerich, JM Bangen, O Govaere, HW Zimmermann, N Gassler, ... Hepatology 59 (2), 630-642, 2014 | 192 | 2014 |
| Origin of regenerating tubular cells after acute kidney injury K Berger, JM Bangen, L Hammerich, C Liedtke, J Floege, B Smeets, ... Proceedings of the National Academy of Sciences 111 (4), 1533-1538, 2014 | 172 | 2014 |
| NLRP3 inflammasome expression is driven by NF-κB in cultured hepatocytes SG Boaru, E Borkham-Kamphorst, E Van de Leur, E Lehnen, C Liedtke, ... Biochemical and biophysical research communications 458 (3), 700-706, 2015 | 164 | 2015 |
| Intestinal dysbiosis augments liver disease progression via NLRP3 in a murine model of primary sclerosing cholangitis L Liao, KM Schneider, EJC Galvez, M Frissen, HU Marschall, H Su, ... Gut 68 (8), 1477-1492, 2019 | 140 | 2019 |
| Loss of caspase-8 protects mice against inflammation-related hepatocarcinogenesis but induces non-apoptotic liver injury C Liedtke, JM Bangen, J Freimuth, N Beraza, D Lambertz, FJ Cubero, ... Gastroenterology 141 (6), 2176-2187, 2011 | 136 | 2011 |
| Hepatocyte-Specific NEMO deletion promotes NK/NKT cell–and TRAIL-dependent liver damage N Beraza, Y Malato, LE Sander, M Al-Masaoudi, J Freimuth, ... Journal of Experimental Medicine 206 (8), 1727-1737, 2009 | 114 | 2009 |
| The anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis … E Borkham-Kamphorst, C Schaffrath, E Van de Leur, U Haas, L Tihaa, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1843 (5), 902-914, 2014 | 111 | 2014 |
| The human caspase-8 promoter sustains basal activity through SP1 and ETS-like transcription factors and can be up-regulated by a p53-dependent mechanism C Liedtke, N Gröger, MP Manns, C Trautwein Journal of Biological Chemistry 278 (30), 27593-27604, 2003 | 110 | 2003 |
| Hepatocyte caspase‐8 is an essential modulator of steatohepatitis in rodents M Hatting, G Zhao, F Schumacher, G Sellge, M Al Masaoudi, N Gaβler, ... Hepatology 57 (6), 2189-2201, 2013 | 109 | 2013 |
| The role of TNF and Fas dependent signaling in animal models of inflammatory liver injury and liver cancer C Liedtke, C Trautwein European journal of cell biology 91 (6-7), 582-589, 2012 | 105 | 2012 |
| Pharmacological IKK2 inhibition blocks liver steatosis and initiation of non-alcoholic steatohepatitis N Beraza, Y Malato, S Vander Borght, C Liedtke, HE Wasmuth, M Dreano, ... Gut 57 (5), 655-663, 2008 | 103 | 2008 |
| Combined activities of JNK1 and JNK2 in hepatocytes protect against toxic liver injury FJ Cubero, ME Zoubek, W Hu, J Peng, G Zhao, YA Nevzorova, ... Gastroenterology 150 (4), 968-981, 2016 | 102 | 2016 |
| Dioxin increases C/EBPβ transcription by activating cAMP/protein kinase A CFA Vogel, E Sciullo, S Park, C Liedtke, C Trautwein, F Matsumura Journal of Biological Chemistry 279 (10), 8886-8894, 2004 | 99 | 2004 |
| TRAIL receptor deletion in mice suppresses the inflammation of nutrient excess L Idrissova, H Malhi, NW Werneburg, NK LeBrasseur, SF Bronk, C Fingas, ... Journal of hepatology 62 (5), 1156-1163, 2015 | 90 | 2015 |
| Lack of interleukin‐6/glycoprotein 130/signal transducers and activators of transcription‐3 signaling in hepatocytes predisposes to liver steatosis and injury in mice DC Kroy, N Beraza, DF Tschaharganeh, LE Sander, S Erschfeld, ... Hepatology 51 (2), 463-473, 2010 | 89 | 2010 |
Frank TackeProfessor of Medicine, Charité University Medicine BerlinVerified email at charite.de
