| ER stress triggers apoptosis by activating BH3-only protein Bim H Puthalakath, LA O'Reilly, P Gunn, L Lee, PN Kelly, ND Huntington, ... Cell 129 (7), 1337-1349, 2007 | 1667 | 2007 |
| Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice N Motoyama, F Wang, KA Roth, H Sawa, K Nakayama, K Nakayama, ... Science 267 (5203), 1506-1510, 1995 | 1517 | 1995 |
| Foxo3a is essential for maintenance of the hematopoietic stem cell pool K Miyamoto, KY Araki, K Naka, F Arai, K Takubo, S Yamazaki, S Matsuoka, ... Cell stem cell 1 (1), 101-112, 2007 | 986 | 2007 |
| DNA damage-induced G2–M checkpoint activation by histone H2AX and 53BP1 O Fernandez-Capetillo, HT Chen, A Celeste, I Ward, PJ Romanienko, ... Nature cell biology 4 (12), 993-997, 2002 | 832 | 2002 |
| TGF-β–FOXO signalling maintains leukaemia-initiating cells in chronic myeloid leukaemia K Naka, T Hoshii, T Muraguchi, Y Tadokoro, T Ooshio, Y Kondo, S Nakao, ... Nature 463 (7281), 676-680, 2010 | 698 | 2010 |
| Essential role for ZAP-70 in both positive and negative selection of thymocytes I Negishi, N Motoyama, K Nakayama, K Nakayama, S Senju, ... Nature 376 (6539), 435-438, 1995 | 662 | 1995 |
| Aberrant cell cycle checkpoint function and early embryonic death in Chk1−/− mice H Takai, K Tominaga, N Motoyama, YA Minamishima, H Nagahama, ... Genes & development 14 (12), 1439-1447, 2000 | 628 | 2000 |
| Bmi1 regulates mitochondrial function and the DNA damage response pathway J Liu, L Cao, J Chen, S Song, IH Lee, C Quijano, H Liu, K Keyvanfar, ... Nature 459 (7245), 387-392, 2009 | 522 | 2009 |
| Chk2‐deficient mice exhibit radioresistance and defective p53‐mediated transcription H Takai, K Naka, Y Okada, M Watanabe, N Harada, S Saito, ... The EMBO journal, 2002 | 518 | 2002 |
| NAK is an IκB kinase-activating kinase Y Tojima, A Fujimoto, M Delhase, Y Chen, S Hatakeyama, K Nakayama, ... Nature 404 (6779), 778-782, 2000 | 498 | 2000 |
| Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice T Furuyama, K Kitayama, Y Shimoda, M Ogawa, K Sone, K Yoshida-Araki, ... Journal of Biological Chemistry 279 (33), 34741-34749, 2004 | 408 | 2004 |
| SIRT1 is critical regulator of FOXO-mediated transcription in response to oxidative stress Y Kobayashi, Y Furukawa-Hibi, C Chen, Y Horio, K Isobe, K Ikeda, ... International journal of molecular medicine 16 (2), 237-243, 2005 | 398 | 2005 |
| Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress IH Lee, Y Kawai, MM Fergusson, II Rovira, AJR Bishop, N Motoyama, ... Science 336 (6078), 225-228, 2012 | 359 | 2012 |
| FOXO forkhead transcription factors induce G2-M checkpoint in response to oxidative stress Y Furukawa-Hibi, K Yoshida-Araki, T Ohta, K Ikeda, N Motoyama Journal of Biological Chemistry 277 (30), 26729-26732, 2002 | 319 | 2002 |
| DNA damage tumor suppressor genes and genomic instability N Motoyama, K Naka Current opinion in genetics & development 14 (1), 11-16, 2004 | 312 | 2004 |
| Interleukin 15–mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1 ND Huntington, H Puthalakath, P Gunn, E Naik, EM Michalak, MJ Smyth, ... Nature immunology 8 (8), 856-863, 2007 | 295 | 2007 |
| FOXO transcription factors in cell-cycle regulation and the response to oxidative stress Y Furukawa-Hibi, Y Kobayashi, C Chen, N Motoyama Antioxidants & redox signaling 7 (5-6), 752-760, 2005 | 250 | 2005 |
| Necessary and sufficient role for a mitosis skip in senescence induction Y Johmura, M Shimada, T Misaki, A Naiki-Ito, H Miyoshi, N Motoyama, ... Molecular cell 55 (1), 73-84, 2014 | 180 | 2014 |
| Hydrocephalus, situs inversus, chronic sinusitis, and male infertility in DNA polymerase λ-deficient mice: possible implication for the pathogenesis of immotile cilia syndrome Y Kobayashi, M Watanabe, Y Okada, H Sawa, H Takai, M Nakanishi, ... Molecular and cellular biology 22 (8), 2769-2776, 2002 | 173 | 2002 |
| Two rotating cilia in the node cavity are sufficient to break left–right symmetry in the mouse embryo K Shinohara, A Kawasumi, A Takamatsu, S Yoshiba, Y Botilde, ... Nature communications 3 (1), 622, 2012 | 165 | 2012 |
