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Januka Athukoralage
Januka Athukoralage
Senior Scientist, Arc Institute
Verified email at ucsf.edu - Homepage
Title
Cited by
Cited by
Year
An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity
JS Athukoralage, SA McMahon, C Zhang, S Grüschow, S Graham, ...
Nature 577 (7791), 572-575, 2020
1562020
Control of cyclic oligoadenylate synthesis in a type III CRISPR system
C Rouillon, JS Athukoralage, S Graham, S Grüschow, MF White
Elife 7, e36734, 2018
1482018
Ring nucleases deactivate type III CRISPR ribonucleases by degrading cyclic oligoadenylate
JS Athukoralage, C Rouillon, S Graham, S Grüschow, MF White
Nature 562 (7726), 277-280, 2018
1132018
A type III CRISPR ancillary ribonuclease degrades its cyclic oligoadenylate activator
JS Athukoralage, S Graham, S Grüschow, C Rouillon, MF White
Journal of molecular biology 431 (15), 2894-2899, 2019
752019
Bacteriophages inhibit and evade cGAS-like immune function in bacteria
E Huiting, X Cao, J Ren, JS Athukoralage, Z Luo, S Silas, N An, H Carion, ...
Cell 186 (4), 864-876. e21, 2023
652023
Cyclic oligoadenylate signalling mediates Mycobacterium tuberculosis CRISPR defence
S Grüschow, JS Athukoralage, S Graham, T Hoogeboom, MF White
Nucleic acids research 47 (17), 9259-9270, 2019
612019
The dynamic interplay of host and viral enzymes in type III CRISPR-mediated cyclic nucleotide signalling
JS Athukoralage, S Graham, C Rouillon, S Grüschow, CM Czekster, ...
Elife 9, e55852, 2020
532020
Cyclic nucleotide signaling in phage defense and counter-defense
JS Athukoralage, MF White
Annual Review of Virology 9, 451-468, 2022
472022
Cyclic oligoadenylate signaling and regulation by ring nucleases during type III CRISPR defense
JS Athukoralage, MF White
RNA 27 (8), 855-867, 2021
372021
Investigation of the cyclic oligoadenylate signaling pathway of type III CRISPR systems
C Rouillon, JS Athukoralage, S Graham, S Grüschow, MF White
Methods in Enzymology 616, 191-218, 2019
342019
Tetramerisation of the CRISPR ring nuclease Crn3/Csx3 facilitates cyclic oligoadenylate cleavage
JS Athukoralage, S McQuarrie, S Grüschow, S Graham, TM Gloster, ...
Elife 9, e57627, 2020
292020
Fuse to defuse: a self-limiting ribonuclease-ring nuclease fusion for type III CRISPR defence
A Samolygo, JS Athukoralage, S Graham, MF White
Nucleic Acids Research 48 (11), 6149-6156, 2020
262020
Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open
S McQuarrie, JS Athukoralage, SA McMahon, S Graham, K Ackermann, ...
Nucleic Acids Research 51 (19), 10590-10605, 2023
62023
Structural mechanism of bridge RNA-guided recombination
M Hiraizumi, NT Perry, MG Durrant, T Soma, N Nagahata, S Okazaki, ...
Nature 630 (8018), 994-1002, 2024
42024
Bridge RNAs direct programmable recombination of target and donor DNA
MG Durrant, NT Perry, JJ Pai, AR Jangid, JS Athukoralage, M Hiraizumi, ...
Nature 630 (8018), 984-993, 2024
32024
Ring nuclease
MF White, J Athukoralage
US Patent App. 17/432,201, 2023
2023
Killing the messenger: discovery of enzymes degrading cyclic oligoadenylate defence activators synthesised by type III CRISPR immune systems
JS Athukoralage
University of St Andrews, 2021
2021
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