| A Phase 3 Open-Label Study of Elexacaftor/Tezacaftor/Ivacaftor in Children 6 through 11 Years of Age with Cystic Fibrosis and at Least One F508del Allele ET Zemanick, JL Taylor-Cousar, J Davies, RL Gibson, MA Mall, ... American journal of respiratory and critical care medicine 203 (12), 1522-1532, 2021 | 179 | 2021 |
| LL-37 complexation with glycosaminoglycans in cystic fibrosis lungs inhibits antimicrobial activity, which can be restored by hypertonic saline G Bergsson, EP Reeves, P McNally, SH Chotirmall, CM Greene, P Greally, ... The Journal of Immunology 183 (1), 543-551, 2009 | 166 | 2009 |
| Decreased levels of secretory leucoprotease inhibitor in the Pseudomonas-infected cystic fibrosis lung are due to neutrophil elastase degradation S Weldon, P McNally, NG McElvaney, JS Elborn, DF McAuley, J Wartelle, ... The Journal of Immunology 183 (12), 8148-8156, 2009 | 151 | 2009 |
| The role of short-chain fatty acids, produced by anaerobic bacteria, in the cystic fibrosis airway B Mirković, MA Murray, GM Lavelle, K Molloy, AA Azim, C Gunaratnam, ... American journal of respiratory and critical care medicine 192 (11), 1314-1324, 2015 | 125 | 2015 |
| Elafin, an elastase-specific inhibitor, is cleaved by its cognate enzyme neutrophil elastase in sputum from individuals with cystic fibrosis N Guyot, MW Butler, P McNally, S Weldon, CM Greene, RL Levine, ... Journal of biological chemistry 283 (47), 32377-32385, 2008 | 112 | 2008 |
| Reduced 15-lipoxygenase 2 and lipoxin A4/leukotriene B4 ratio in children with cystic fibrosis FC Ringholz, PJ Buchanan, DT Clarke, RG Millar, M McDermott, ... European Respiratory Journal 44 (2), 394-404, 2014 | 108 | 2014 |
| miR-31 dysregulation in cystic fibrosis airways contributes to increased pulmonary cathepsin S production S Weldon, P McNally, DF McAuley, IK Oglesby, CL Wohlford-Lenane, ... American journal of respiratory and critical care medicine 190 (2), 165-174, 2014 | 93 | 2014 |
| miR-17 overexpression in cystic fibrosis airway epithelial cells decreases interleukin-8 production IK Oglesby, SF Vencken, R Agrawal, K Gaughan, K Molloy, G Higgins, ... European Respiratory Journal 46 (5), 1350-1360, 2015 | 83 | 2015 |
| Anaerobic bacteria cultured from cystic fibrosis airways correlate to milder disease: a multisite study MS Muhlebach, JE Hatch, GG Einarsson, SJ McGrath, DF Gilipin, ... European Respiratory Journal 52 (1), 2018 | 79 | 2018 |
| Vitamin D receptor agonists inhibit pro-inflammatory cytokine production from the respiratory epithelium in cystic fibrosis P McNally, C Coughlan, G Bergsson, M Doyle, C Taggart, L Adorini, ... Journal of cystic fibrosis 10 (6), 428-434, 2011 | 71 | 2011 |
| Active video games as an exercise tool for children with cystic fibrosis C O'Donovan, P Greally, G Canny, P McNally, J Hussey Journal of Cystic Fibrosis 13 (3), 341-346, 2014 | 70 | 2014 |
| The microbial community of the cystic fibrosis airway is disrupted in early life J Renwick, P McNally, B John, T DeSantis, B Linnane, P Murphy, ... PloS one 9 (12), e109798, 2014 | 68 | 2014 |
| Lipoxin A4 Stimulates Calcium-Activated Chloride Currents and Increases Airway Surface Liquid Height in Normal and Cystic Fibrosis Airway Epithelia V Verrière, G Higgins, M Al-Alawi, RW Costello, P McNally, R Chiron, ... PloS one 7 (5), e37746, 2012 | 65 | 2012 |
| Longitudinal trends in real-world outcomes after initiation of ivacaftor. A cohort study from the cystic fibrosis registry of Ireland L Kirwan, G Fletcher, M Harrington, P Jeleniewska, S Zhou, B Casserly, ... Annals of the American Thoracic Society 16 (2), 209-216, 2019 | 60 | 2019 |
| Lipoxin A4-mediated KATP potassium channel activation results in cystic fibrosis airway epithelial repair PJ Buchanan, P McNally, BJ Harvey, V Urbach American Journal of Physiology-Lung Cellular and Molecular Physiology 305 (2 …, 2013 | 55 | 2013 |
| Amikacin liposome inhalation suspension for chronic Pseudomonas aeruginosa infection in cystic fibrosis D Bilton, T Pressler, I Fajac, JP Clancy, D Sands, P Minic, M Cipolli, ... Journal of Cystic Fibrosis 19 (2), 284-291, 2020 | 52 | 2020 |
| High concentrations of pepsin in bronchoalveolar lavage fluid from children with cystic fibrosis are associated with high interleukin-8 concentrations P McNally, E Ervine, MD Shields, BD Dimitrov, B El Nazir, CC Taggart, ... Thorax 66 (2), 140-143, 2011 | 51 | 2011 |
| Precise targeting of miRNA sites restores CFTR activity in CF bronchial epithelial cells C De Santi, EF Fernández, R Gaul, S Vencken, A Glasgow, IK Oglesby, ... Molecular Therapy 28 (4), 1190-1199, 2020 | 47 | 2020 |
| Lipoxin A4 prevents tight junction disruption and delays the colonization of cystic fibrosis bronchial epithelial cells by Pseudomonas aeruginosa G Higgins, CF Torre, J Tyrrell, P McNally, BJ Harvey, V Urbach American Journal of Physiology-Lung Cellular and Molecular Physiology, 2016 | 46 | 2016 |
| Dysregulation of TIM-3–galectin-9 pathway in the cystic fibrosis airways I Vega-Carrascal, EP Reeves, T Niki, T Arikawa, P McNally, SJ O’Neill, ... The Journal of Immunology 186 (5), 2897-2909, 2011 | 46 | 2011 |
