Endothelial reprogramming by disturbed flow revealed by single-cell RNA and chromatin accessibility study A Andueza, S Kumar, J Kim, DW Kang, HL Mumme, JI Perez, N Villa-Roel, ... Cell Reports 33 (11), 108491, 2020 | 123 | 2020 |
Disturbed Flow Increases UBE2C (Ubiquitin E2 Ligase C) via Loss of miR-483-3p, Inducing Aortic Valve Calcification by the pVHL (von Hippel-Lindau Protein) and HIF-1α (Hypoxia … J Fernandez Esmerats, N Villa-Roel, S Kumar, L Gu, MT Salim, M Ohh, ... Arteriosclerosis, Thrombosis, and Vascular Biology 39 (3), 467-481, 2019 | 64 | 2019 |
Stable flow-induced expression of KLK10 inhibits endothelial inflammation and atherosclerosis D Williams, M Mahmoud, R Liu, A Andueza, S Kumar, DW Kang, J Zhang, ... eLife 11, e72579, 2022 | 27 | 2022 |
Hypoxia inducible factor 1α inhibitor PX-478 reduces atherosclerosis in mice N Villa-Roel, K Ryu, L Gu, JF Esmerats, DW Kang, S Kumar, H Jo Atherosclerosis, 2022 | 17 | 2022 |
miR-214 is stretch-sensitive in aortic valve and inhibits aortic valve calcification MT Salim, JF Esmerats, S Arjunon, N Villa-Roel, RM Nerem, H Jo, ... Annals of biomedical engineering 47, 1106-1115, 2019 | 15 | 2019 |
Sox13 is a novel flow-sensitive transcription factor that prevents inflammation by repressing chemokine expression in endothelial cells C Demos, J Johnson, A Andueza, C Park, Y Kim, N Villa-Roel, DW Kang, ... Frontiers in Cardiovascular Medicine 9, 979745, 2022 | 5 | 2022 |
HIF1A inhibitor PX-478 reduces pathological stretch-induced calcification and collagen turnover in aortic valve MT Salim, N Villa-Roel, B Vogel, H Jo, AP Yoganathan Frontiers in Cardiovascular Medicine 9, 1002067, 2022 | 4 | 2022 |
Isolation of Endothelial Cells from the Lumen of Mouse Carotid Arteries for Single-cell Multi-omics Experiments S Kumar, A Andueza, N Villa-Roel, J Kim, DW Kang, H Jo JoVE (Journal of Visualized Experiments), e63128, 2021 | 4 | 2021 |
Role of Biomechanical Stress and Mechanosensitive miRNAs in Calcific Aortic Valve Disease N Villa-Roel, K Ryu, H Jo Cardiovascular Calcification and Bone Mineralization, 117-135, 2020 | 2 | 2020 |
HEG1 Protects Against Atherosclerosis by Regulating Stable Flow-Induced KLF2/4 Expression in Endothelial Cells IA Tamargo, K In Baek, C Xu, D Won Kang, Y Kim, A Andueza, D Williams, ... Circulation, 2023 | 1 | 2023 |
Single-Cell RNA sequencing investigation of female-male differences under PAD conditions GS Marrero, N Villa-Roel, F Li, C Park, DW Kang, KE Hekman, H Jo, ... Frontiers in Cardiovascular Medicine 10, 2023 | 1 | 2023 |
Hypoxia Inducible Factor-1α Inhibitor, PX-478, Reduces Atherosclerosis in vivo N Villa-Roel, L Gu, J Fernandez Esmerats, DW Kang, S Kumar, H Jo Arteriosclerosis, Thrombosis, and Vascular Biology 40 (Suppl_1), A366-A366, 2020 | 1 | 2020 |
Myeloid CCN3 protects against aortic valve calcification P Tu, Q Xu, X Zhou, N Villa-Roel, S Kumar, N Dong, H Jo, C Ou, Z Lin Cell Communication and Signaling 21 (1), 1-15, 2023 | | 2023 |
Flow-Induced Cellular Reprogramming in Mouse Atherosclerosis Model C Park, N Villa-Roel, K JEONG, KI Baek, Y Kim, A Andueza, H Zepeda, ... Circulation 148 (Suppl_1), A12147-A12147, 2023 | | 2023 |
Methods and compositions for managing vascular conditions using miR-483 mimics and HIF1alpha pathway inhibitors H Jo, JF ESMERATS, N Villa-Roel US Patent 11,225,660, 2022 | | 2022 |
Abstract MP41: Myeloid Ccn3 Protects Against Aortic Valve Calcification P Tu, Z Lin, xianming zhou, H Jo, N Villa-roel, S Kumar, C Ou, N Dong Arteriosclerosis, Thrombosis, and Vascular Biology 41 (Suppl_1), AMP41-AMP41, 2021 | | 2021 |
Stable Flow-Induced Expression of KLK10 Inhibits Endothelial Inflammation and Atherosclerosis D Williams, M Mahmoud, R Liu, A Andueza, S Kumar, DW Kang, J Zhang, ... bioRxiv, 2021 | | 2021 |
Endothelial reprogramming by disturbed flow revealed by single-cell RNA and chromatin accessibility study. Cell Rep 33: 108491 A Andueza, S Kumar, J Kim, DW Kang, HL Mumme, JI Perez, N Villa-Roel, ... | | 2020 |