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Alfred Kihoon Lee
Alfred Kihoon Lee
Scientist at Sanofi
Verified email at sanofi.com
Title
Cited by
Cited by
Year
Aβ-Induced Drp1 phosphorylation through Akt activation promotes excessive mitochondrial fission leading to neuronal apoptosis
DI Kim, KH Lee, AA Gabr, GE Choi, JS Kim, SH Ko, HJ Han
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (11), 2820-2834, 2016
1642016
Regulation of stem cell fate by ROS-mediated alteration of metabolism
JM Ryu, HJ Lee, YH Jung, KH Lee, DI Kim, JY Kim, SH Ko, GE Choi, ...
International journal of stem cells 8 (1), 24, 2015
592015
Amyloid β1-42 (Aβ1-42) induces the CDK2-mediated phosphorylation of tau through the activation of the mTORC1 signaling pathway while promoting neuronal cell death
KH Lee, SJ Lee, HJ Lee, GE Choi, YH Jung, DI Kim, AA Gabr, JM Ryu, ...
Frontiers in molecular neuroscience 10, 229, 2017
532017
IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2α
Y Tanabe, Y Naito, C Vasuta, AK Lee, Y Soumounou, MW Linhoff, ...
Nature communications 8 (1), 408, 2017
422017
Amyloid-β oligomers interact with neurexin and diminish neurexin-mediated excitatory presynaptic organization
Y Naito, Y Tanabe, AK Lee, E Hamel, H Takahashi
Scientific reports 7 (1), 42548, 2017
352017
Emerging roles of the neurotrophin receptor TrkC in synapse organization
Y Naito, AK Lee, H Takahashi
Neuroscience research 116, 10-17, 2017
342017
Glycerol-3-phosphate acyltransferase-1 upregulation by O-GlcNAcylation of Sp1 protects against hypoxia-induced mouse embryonic stem cell apoptosis via mTOR activation
HJ Lee, JM Ryu, YH Jung, KH Lee, DI Kim, HJ Han
Cell Death & Disease 7 (3), e2158-e2158, 2016
342016
Relationship between β-amyloid and mitochondrial dynamics
DI Kim, KH Lee, JY Oh, JS Kim, HJ Han
Cellular and Molecular Neurobiology 37, 955-968, 2017
222017
Synaptic organizers in Alzheimer’s disease: A classification based on amyloid-β sensitivity
AK Lee, H Khaled, N Chofflet, H Takahashi
Frontiers in Cellular Neuroscience 14, 281, 2020
92020
α-Synuclein preformed fibrils bind to β-neurexins and impair β-neurexin-mediated presynaptic organization
B Feller, A Fallon, W Luo, PT Nguyen, I Shlaifer, AK Lee, N Chofflet, N Yi, ...
Cells 12 (7), 1083, 2023
62023
SorCS1 inhibits amyloid-β binding to neurexin and rescues amyloid-β–induced synaptic pathology
AK Lee, N Yi, H Khaled, B Feller, H Takahashi
Life Science Alliance 6 (4), 2023
52023
Characterization of Amyloidβ-Neurexin interaction in Alzheimer’s disease
A Lee
McGill University, 2022
2022
Pathological roles of neurexins in alpha-synuclein pathology in Parkinson's disease and Lewy body dementias
A Fallon, A Lee, Y Naito, H Takahashi
JOURNAL OF NEUROCHEMISTRY 150, 213-213, 2019
2019
Determination of amyloid-beta oligomers effects on the CBLN1-neurexin synaptic organizing complex in Alzheimer's disease
H Khaled, J Lacouchie-Payen, A Lee, S Bichara-Allard, H Takahashi
JOURNAL OF NEUROCHEMISTRY 150, 215-216, 2019
2019
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Articles 1–14