| Sturge–Weber syndrome and port-wine stains caused by somatic mutation in GNAQ MD Shirley, H Tang, CJ Gallione, JD Baugher, LP Frelin, B Cohen, ... New England Journal of Medicine 368 (21), 1971-1979, 2013 | 1044 | 2013 |
| CRISPR screens provide a comprehensive assessment of cancer vulnerabilities but generate false-positive hits for highly amplified genomic regions DM Munoz, PJ Cassiani, L Li, E Billy, JM Korn, MD Jones, J Golji, ... Cancer discovery 6 (8), 900-913, 2016 | 376 | 2016 |
| Construction of human activity-based phosphorylation networks RH Newman, J Hu, HS Rho, Z Xie, C Woodard, J Neiswinger, C Cooper, ... Molecular Systems Biology 9 (1), 2013 | 186 | 2013 |
| Vascular anomalies caused by abnormal signaling within endothelial cells: targets for novel therapies HL Nguyen, LM Boon, M Vikkula Seminars in interventional radiology 34 (03), 233-238, 2017 | 58 | 2017 |
| Hyperactivation of MAPK signaling is deleterious to RAS/RAF-mutant melanoma GP Leung, T Feng, FD Sigoillot, FC Geyer, MD Shirley, DA Ruddy, ... Molecular Cancer Research 17 (1), 199-211, 2019 | 55 | 2019 |
| Chromosomal variation in lymphoblastoid cell lines MD Shirley, JD Baugher, EL Stevens, Z Tang, N Gerry, CM Beiswanger, ... Human mutation 33 (7), 1075-1086, 2012 | 51 | 2012 |
| Efficient" pythonic" access to FASTA files using pyfaidx MD Shirley, Z Ma, BS Pedersen, SJ Wheelan PeerJ PrePrints, 2015 | 49 | 2015 |
| Tumor intrinsic efficacy by SHP2 and RTK inhibitors in KRAS-mutant cancers HX Hao, H Wang, C Liu, S Kovats, R Velazquez, H Lu, B Pant, M Shirley, ... Molecular cancer therapeutics 18 (12), 2368-2380, 2019 | 39 | 2019 |
| Inhibition of MDM2 promotes antitumor responses in p53 wild-type cancer cells through their interaction with the immune and stromal microenvironment HQ Wang, IJ Mulford, F Sharp, J Liang, S Kurtulus, G Trabucco, DS Quinn, ... Cancer Research 81 (11), 3079-3091, 2021 | 36 | 2021 |
| Sensitive and specific detection of mosaic chromosomal abnormalities using the parent-of-origin-based detection (POD) method JD Baugher, BD Baugher, MD Shirley, J Pevsner BMC genomics 14, 1-22, 2013 | 25 | 2013 |
| A phase I trial of LXS196, a protein kinase C (PKC) inhibitor, for metastatic uveal melanoma S Piperno-Neumann, MS Carlino, V Boni, D Loirat, FM Speetjens, JJ Park, ... British journal of cancer 128 (6), 1040-1051, 2023 | 19 | 2023 |
| The discovery of SWI/SNF chromatin remodeling activity as a novel and targetable dependency in uveal melanoma F Rago, GN Elliott, A Li, K Sprouffske, G Kerr, A Desplat, D Abramowski, ... Molecular cancer therapeutics 19 (10), 2186-2195, 2020 | 19 | 2020 |
| Unexpected relationships and inbreeding in HapMap phase III populations EL Stevens, JD Baugher, MD Shirley, LP Frelin, J Pevsner PloS one 7 (11), e49575, 2012 | 14 | 2012 |
| Copy number variants associated with 14 cases of self-injurious behavior MD Shirley, L Frelin, JS López, A Jedlicka, A Dziedzic, ... PloS one 11 (3), e0149646, 2016 | 9 | 2016 |
| Efficient ‘pythonic’access to FASTA files using pyfaidx PeerJ PrePrints MD Shirley, Z Ma, BS Pedersen, SJ Wheelan | 5 | 2015 |
| PISCES: a package for rapid quantitation and quality control of large scale mRNA-seq datasets MD Shirley, VK Radhakrishna, J Golji, JM Korn bioRxiv, 2020.12. 01.390575, 2020 | 4 | 2020 |
| RAF-mutant melanomas differentially depend on ERK2 over ERK1 to support aberrant MAPK pathway activation and cell proliferation MS Crowe, T Zavorotinskaya, CF Voliva, MD Shirley, Y Wang, DA Ruddy, ... Molecular Cancer Research 19 (6), 1063-1075, 2021 | 3 | 2021 |
| FGFR1 mosaic pathogenic variant in encephalocraniocutaneous lipomatosis with leptomeningeal Angiomatosis MGG de la Banda, P Fernández-Álvarez, ÁSM García-Carpintero, ... Journal of Pediatric Neurology 18 (05), 258-262, 2020 | 1 | 2020 |
| Concerns regarding" Whole exome sequencing reveals minimal differences between cell line and whole blood derived DNA". MD Shirley Genomics 102 (4), 430-430, 2013 | 1 | 2013 |
| INPP5A phosphatase is a synthetic lethal target in GNAQ and GNA11-mutant melanomas AMO Elbatsh, A Amin-Mansour, A Haberkorn, C Textor, N Ebel, E Renard, ... Nature cancer, 1-19, 2024 | | 2024 |
Joseph D. BaugherCenter for Food Safety and Applied Nutrition, US FDAVerified email at fda.hhs.gov
