| Ovarian cancer-associated mutations disable catalytic activity of CDK12, a kinase that promotes homologous recombination repair and resistance to cisplatin and poly (ADP-ribose … PM Joshi, SL Sutor, CJ Huntoon, LM Karnitz Journal of Biological Chemistry 289 (13), 9247-9253, 2014 | 207 | 2014 |
| m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development Immunity 52, 1-15, 2020 | 121* | 2020 |
| SRSF2 mutations drive oncogenesis by activating a global program of aberrant alternative splicing in hematopoietic cells Y Liang, T Tebaldi, K Rejeski, P Joshi, G Stefani, A Taylor, Y Song, ... Leukemia 32 (12), 2659-2671, 2018 | 73 | 2018 |
| Genomically incorporated 5-fluorouracil that escapes UNG-initiated base excision repair blocks DNA replication and activates homologous recombination AM Huehls, CJ Huntoon, PM Joshi, CA Baehr, JM Wagner, X Wang, ... Molecular pharmacology 89 (1), 53-62, 2016 | 58 | 2016 |
| How do messenger RNA splicing alterations drive myelodysplasia? P Joshi, S Halene, O Abdel-Wahab Blood, The Journal of the American Society of Hematology 129 (18), 2465-2470, 2017 | 36 | 2017 |
| Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies G Biancon, P Joshi, JT Zimmer, T Hunck, Y Gao, MD Lessard, ... Molecular cell 82 (6), 1107-1122. e7, 2022 | 28 | 2022 |
| Visualization of herpes simplex virus type 1 virions using fluorescent colors L Etienne, P Joshi, L Dingle, E Huang, P Grzesik, PJ Desai Journal of virological methods 241, 46-51, 2017 | 11 | 2017 |
| Incorporation of the Kaposi’s sarcoma-associated herpesvirus capsid vertex-specific component (CVSC) into self-assembled capsids P Grzesik, D MacMath, B Henson, S Prasad, P Joshi, PJ Desai Virus research 236, 9-13, 2017 | 9 | 2017 |
| Multi-omics profiling of U2AF1 mutants dissects pathogenic mechanisms affecting RNA granules in myeloid malignancies G Biancon, P Joshi, JT Zimmer, T Hunck, Y Gao, MD Lessard, ... bioRxiv, 2021.04. 22.441020, 2021 | 3 | 2021 |
| Mettl3 mediated m6A modification is essential in fetal hematopoiesis Y Gao, R Vasic, T Tebaldi, Y Song, R Teng, P Joshi, G Viero, A Xiao, ... Blood 132, 3825, 2018 | 3 | 2018 |
| Deconvolution of in vivo protein-RNA contacts using fractionated eCLIP-seq G Biancon, E Busarello, P Joshi, BJ Lesch, S Halene, T Tebaldi STAR protocols 3 (4), 101823, 2022 | 1 | 2022 |
| U2AF1 Mutations Enhance Stress Granule Response in Myeloid Malignancies G Biancon, P Joshi, JT Zimmer, T Hunck, Y Gao, MD Lessard, ... Blood 138 (Supplement 1), 321-321, 2021 | | 2021 |
| High-Resolution Binding Atlas of U2AF1 Mutants Uncovers New Complexity in Splicing Alterations and Kinetics in Myeloid Malignancies Blood 136 (Supplement 1), 3-4, 2020 | | 2020 |
| U2AF1 Driver Mutations in Hematopoietic Disorders Alter but Do Not Abrogate RNA Binding and Enlighten Structural Dependencies of the U2AF-RNA Complex G Biancon, P Joshi, T Hunck, Y Gao, V Botti, A Qin, M Sadykov, X Wang, ... Blood 134, 1230, 2019 | | 2019 |
| Loss of METTL3 Mediated m6A RNA Modification Results in Double-Stranded RNA Induced Innate Immune Response and Hematopoietic Failure Y Gao, R Vasic, Y Song, R Teng, R Gbyli, G Biancon, R Nelakanti, E Kudo, ... Blood 134, 450, 2019 | | 2019 |
| Abstract POSTER-BIOL-1325: Ovarian cancer-associated CDK12 mutations disable its kinase activity and cause defects in homologous recombination PM Joshi, SL Sutor, CJ Huntoon, LM Karnitz Clinical Cancer Research 21 (16_Supplement), POSTER-BIOL-1325-POSTER-BIOL-1325, 2015 | | 2015 |
