Lysophosphatidylcholine regulates sexual stage differentiation in the human malaria parasite Plasmodium falciparum NMB Brancucci, JP Gerdt, CQ Wang, M De Niz, N Philip, SR Adapa, ... Cell 171 (7), 1532-1544. e15, 2017 | 299 | 2017 |
Competition studies confirm two major barriers that can preclude the spread of resistance to quorum-sensing inhibitors in bacteria JP Gerdt, HE Blackwell ACS chemical biology 9 (10), 2291-2299, 2014 | 140 | 2014 |
Mating in the closest living relatives of animals is induced by a bacterial chondroitinase A Woznica, JP Gerdt, RE Hulett, J Clardy, N King Cell 170 (6), 1175-1183. e11, 2017 | 113 | 2017 |
Active Efflux Influences the Potency of Quorum Sensing Inhibitors in Pseudomonas aeruginosa JD Moore, JP Gerdt, NR Eibergen, HE Blackwell ChemBioChem 15 (3), 435-442, 2014 | 77 | 2014 |
Mutational analysis of the quorum-sensing receptor LasR reveals interactions that govern activation and inhibition by nonlactone ligands JP Gerdt, CE McInnis, TL Schell, FM Rossi, HE Blackwell Chemistry & biology 21 (10), 1361-1369, 2014 | 49 | 2014 |
Chemical interrogation of LuxR-type quorum sensing receptors reveals new insights into receptor selectivity and the potential for interspecies bacterial signaling JP Gerdt, DM Wittenwyler, JB Combs, ME Boursier, JW Brummond, H Xu, ... ACS chemical biology 12 (9), 2457-2464, 2017 | 33 | 2017 |
Unraveling the contributions of hydrogen-bonding interactions to the activity of native and non-native ligands in the quorum-sensing receptor LasR JP Gerdt, CE McInnis, TL Schell, HE Blackwell Organic & biomolecular chemistry 13 (5), 1453-1462, 2015 | 29 | 2015 |
Controlling the direction of site-selectivity and regioselectivity in RNA ligation by Zn 2+-dependent deoxyribozymes that use 2′, 3′-cyclic phosphate RNA substrates DM Kost, JP Gerdt, PI Pradeepkumar, SK Silverman Organic & biomolecular chemistry 6 (23), 4391-4398, 2008 | 25 | 2008 |
Controlling the direction of site-selectivity and regioselectivity in RNA ligation by Zn 2+-dependent deoxyribozymes that use 2′, 3′-cyclic phosphate RNA substrates DM Kost, JP Gerdt, PI Pradeepkumar, SK Silverman Organic & biomolecular chemistry 6 (23), 4391-4398, 2008 | 25 | 2008 |
Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut Q Zhang, V Linke, KA Overmyer, LL Traeger, K Kasahara, IJ Miller, ... Nature microbiology 8 (3), 424-440, 2023 | 21 | 2023 |
Competition studies confirm two major barriers that can preclude the spread of resistance to quorum-sensing inhibitors in bacteria. ACS Chem Biol 9: 2291–2299 JP Gerdt, HE Blackwell | 9 | 2014 |
Research tales from the Clardy laboratory: Function-driven natural product discovery TTH Fukuda, CD Cassilly, JP Gerdt, MT Henke, EJN Helfrich, E Mevers Journal of natural products 83 (3), 744-755, 2020 | 6 | 2020 |
Chemical factors induce aggregative multicellularity in a close unicellular relative of animals N Ros-Rocher, RQ Kidner, C Gerdt, WS Davidson, I Ruiz-Trillo, JP Gerdt Proceedings of the National Academy of Sciences 120 (18), e2216668120, 2023 | 5 | 2023 |
Selective stabilization of natively folded RNA structure by DNA constraints JP Gerdt, CV Miduturu, SK Silverman Journal of the American Chemical Society 130 (45), 14920-14921, 2008 | 3 | 2008 |
A Metabolite Produced by Gut Microbes Represses Phage Infections in Vibrio cholerae Z Zang, KJ Park, JP Gerdt ACS Chemical Biology 17 (9), 2396-2403, 2022 | 1 | 2022 |
An aphrodisiac produced by Vibrio fischeri stimulates mating in the closest living relatives of animals A Woznica, JP Gerdt, RE Hulett, J Clardy, N King bioRxiv, 139022, 2017 | 1 | 2017 |
Interbacterial Biofilm Competition through a Suite of Secreted Metabolites S Rayi, Y Cai, JL Greenwich, C Fuqua, JP Gerdt ACS Chemical Biology, 2024 | | 2024 |
Host lipids regulate multicellular behavior of a predator of a human pathogen RQ Kidner, EB Goldstone, MR Laidemitt, MC Sanchez, C Gerdt, ... bioRxiv, 2024.01. 31.578218, 2024 | | 2024 |
Bacterium secretes chemical inhibitor that sensitizes competitor to bacteriophage infection Z Zang, C Zhang, KJ Park, DA Schwartz, R Podicheti, JT Lennon, ... bioRxiv, 2024.01. 31.578241, 2024 | | 2024 |
Ravidomycin Analogs from Streptomyces sp. Exhibit Altered Antimicrobial and Cytotoxic Selectivity KJ Park, S Maier, C Zhang, SAH Dixon, DB Rusch, MT Pupo, SP Angus, ... Journal of Natural Products 86 (8), 1968-1979, 2023 | | 2023 |