Increased LRRK2 kinase activity alters neuronal autophagy by disrupting the axonal transport of autophagosomes CA Boecker, J Goldsmith, D Dou, GG Cajka, ELF Holzbaur Current Biology 31 (10), 2140-2154. e6, 2021 | 114 | 2021 |
Transient opening of the perineurial barrier for analgesic drug delivery D Hackel, SM Krug, RS Sauer, SA Mousa, A Böcker, D Pflücke, EJ Wrede, ... Proceedings of the National Academy of Sciences 109 (29), E2018-E2027, 2012 | 107 | 2012 |
Actin cables and comet tails organize mitochondrial networks in mitosis AS Moore, SM Coscia, CL Simpson, FE Ortega, EC Wait, JM Heddleston, ... Nature 591 (7851), 659-664, 2021 | 100 | 2021 |
A peptidomimetic tight junction modulator to improve regional analgesia D Zwanziger, D Hackel, C Staat, A Böcker, A Brack, M Beyermann, ... Molecular pharmaceutics 9 (6), 1785-1794, 2012 | 59 | 2012 |
ToolBox: Live Imaging of intracellular organelle transport in induced pluripotent stem cell‐derived neurons CA Boecker, MA Olenick, ER Gallagher, ME Ward, ELF Holzbaur Traffic 21 (1), 138-155, 2020 | 42 | 2020 |
Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing BF Vahsen, VT Ribas, J Sundermeyer, A Boecker, V Dambeck, C Lenz, ... Cell Death & Differentiation 27 (10), 2810-2827, 2020 | 38 | 2020 |
Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy LM Strong, C Chang, JF Riley, CA Boecker, TG Flower, CZ Buffalo, X Ren, ... Elife 10, e70372, 2021 | 34 | 2021 |
Vesicular degradation pathways in neurons: at the crossroads of autophagy and endo-lysosomal degradation CA Boecker, ELF Holzbaur Current opinion in neurobiology 57, 94-101, 2019 | 21 | 2019 |
TUBB4A mutations result in both glial and neuronal degeneration in an H-ABC leukodystrophy mouse model S Sase, AA Almad, CA Boecker, P Guedes-Dias, JJ Li, A Takanohashi, ... Elife 9, e52986, 2020 | 18 | 2020 |
Hyperactive LRRK2 kinase impairs the trafficking of axonal autophagosomes CA Boecker, ELF Holzbaur Autophagy 17 (8), 2043-2045, 2021 | 15 | 2021 |
Regulatory imbalance between LRRK2 kinase, PPM1H phosphatase, and ARF6 GTPase disrupts the axonal transport of autophagosomes D Dou, EM Smith, CS Evans, CA Boecker, ELF Holzbaur Cell Reports 42 (5), 2023 | 12 | 2023 |
The role of LRRK2 in intracellular organelle dynamics CA Boecker Journal of Molecular Biology 435 (12), 167998, 2023 | 7 | 2023 |
Distinct adaptations revealed by unbiased proteomic analysis of autophagy cargos in the brain in PINK1 and LRRK2 models of Parkinson’s disease J Goldsmith, A Ordureau, AKH Stavoe, CA Boecker, M Arany, JW Harper, ... bioRxiv, 2022.10. 03.510717, 2022 | | 2022 |