High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages W Hoepel, HJ Chen, CE Geyer, S Allahverdiyeva, XD Manz, SW de Taeye, ... Science translational medicine 13 (596), eabf8654, 2021 | 228* | 2021 |
High-throughput functional genetic and compound screens identify targets for senescence induction in cancer L Wang, RL de Oliveira, C Wang, JMF Neto, S Mainardi, B Evers, ... Cell reports 21 (3), 773-783, 2017 | 184 | 2017 |
Macrophage subsets in atherosclerosis as defined by single‐cell technologies L Willemsen, MPJ de Winther The Journal of pathology 250 (5), 705-714, 2020 | 161 | 2020 |
Trained immunity-promoting nanobiologic therapy suppresses tumor growth and potentiates checkpoint inhibition B Priem, MMT van Leent, AJP Teunissen, AM Sofias, VP Mourits, ... Cell 183 (3), 786-801. e19, 2020 | 107 | 2020 |
Impact of cholesterol on proinflammatory monocyte production by the bone marrow LCA Stiekema, L Willemsen, Y Kaiser, KHM Prange, NJ Wareham, ... European Heart Journal 42 (42), 4309-4320, 2021 | 39 | 2021 |
Myeloid CD40 deficiency reduces atherosclerosis by impairing macrophages’ transition into a pro-inflammatory state LA Bosmans, CM van Tiel, SABM Aarts, L Willemsen, J Baardman, ... Cardiovascular research 119 (5), 1146-1160, 2023 | 20 | 2023 |
Targeting epigenetics as atherosclerosis treatment: an updated view AE Neele, L Willemsen, HJ Chen, KE Dzobo, MPJ de Winther Current opinion in lipidology 31 (6), 324-330, 2020 | 16 | 2020 |
Peritoneal macrophages have an impaired immune response in obesity which can be reversed by subsequent weight loss L Willemsen, AE Neele, S Van Der Velden, KHM Prange, M Den Toom, ... BMJ Open Diabetes Research and Care 7 (1), e000751, 2019 | 15 | 2019 |
Monocyte and macrophage lipid accumulation results in down-regulated type-I interferon responses L Willemsen, HJ Chen, CPAA van Roomen, GR Griffith, R Siebeler, ... Frontiers in Cardiovascular Medicine 9, 169, 2022 | 11 | 2022 |
Hematopoietic somatic mosaicism is associated with an increased risk of postoperative atrial fibrillation S Ninni, D Dombrowicz, T Kuznetsova, R Vicario, V Gao, O Molendi-Coste, ... Journal of the American College of Cardiology 81 (13), 1263-1278, 2023 | 9 | 2023 |
Deficiency of T cell CD40L has minor beneficial effects on obesity-induced metabolic dysfunction ME Reiche, M Den Toom, L Willemsen, B Van Os, MJJ Gijbels, N Gerdes, ... BMJ Open Diabetes Research and Care 7 (1), e000829, 2019 | 8 | 2019 |
DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atherosclerotic plaque stability L Willemsen, KHM Prange, AE Neele, CPAA van Roomen, M Gijbels, ... Cell Reports 41 (8), 111703, 2022 | 3 | 2022 |
Antigen-specificity measurements are the key to understanding T cell responses R Tippalagama, LY Chihab, K Kearns, S Lewis, S Panda, L Willemsen, ... Frontiers in immunology 14, 1127470, 2023 | 2 | 2023 |
Targeting the ACOD1-itaconate axis stabilizes atherosclerotic plaques KJ Harber, AE Neele, CPAA van Roomen, MJJ Gijbels, L Beckers, ... Redox Biology 70, 103054, 2024 | 1 | 2024 |
A multi-omics systems vaccinology resource to develop and test computational models of immunity P Shinde, F Soldevila, J Reyna, M Aoki, M Rasmussen, L Willemsen, ... Cell Reports Methods 4 (3), 2024 | | 2024 |