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Siddhartha Mitra
Siddhartha Mitra
Chief Medical Officer, Trishula Therapeutics
Verified email at trishulatx.com
Title
Cited by
Cited by
Year
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
M Arrasate, S Mitra, ES Schweitzer, MR Segal, S Finkbeiner
Nature 431 (7010), 805-810, 2004
23992004
A phase 2 study of idelalisib plus rituximab in treatment-naive older patients with chronic lymphocytic leukemia
SM O'Brien, N Lamanna, TJ Kipps, I Flinn, AD Zelenetz, JA Burger, ...
Blood 126 (25), 2686-2694, 2015
3002015
Identifying polyglutamine protein species in situ that best predict neurodegeneration
J Miller, M Arrasate, E Brooks, CP Libeu, J Legleiter, D Hatters, J Curtis, ...
Nature chemical biology 7 (12), 925-934, 2011
2322011
Final results of a randomized, phase III study of rituximab with or without idelalisib followed by open-label idelalisib in patients with relapsed chronic lymphocytic leukemia
JP Sharman, SE Coutre, RR Furman, BD Cheson, JM Pagel, P Hillmen, ...
Journal of Clinical Oncology 37 (16), 1391-1402, 2019
2212019
AMPA receptors regulate transcription of the plasticity-related immediate-early gene Arc
VR Rao, SA Pintchovski, J Chin, CL Peebles, S Mitra, S Finkbeiner
Nature neuroscience 9 (7), 887-895, 2006
2172006
Quantitative relationships between huntingtin levels, polyglutamine length, inclusion body formation, and neuronal death provide novel insight into huntington's disease …
J Miller, M Arrasate, BA Shaby, S Mitra, E Masliah, S Finkbeiner
Journal of Neuroscience 30 (31), 10541-10550, 2010
1942010
Single neuron ubiquitin-proteasome dynamics accompanying inclusion body formation in huntington disease
S Mitra, AS Tsvetkov, S Finkbeiner
Journal of Biological Chemistry 284 (7), 4398-4403, 2009
1152009
The ubiquitin-proteasome pathway in Huntington's disease
S Mitra, S Finkbeiner
The Scientific World Journal 8, 421-433, 2008
882008
Randomized double-blind placebo-controlled phase 2 study of bemarituzumab combined with modified FOLFOX6 (mFOLFOX6) in first-line (1L) treatment of advanced gastric …
ZA Wainberg, PC Enzinger, YK Kang, K Yamaguchi, S Qin, KW Lee, ...
Journal of Clinical Oncology 39 (3_suppl), 160-160, 2021
802021
Disease-associated polyglutamine stretches in monomeric huntingtin adopt a compact structure
C Peters-Libeu, J Miller, E Rutenber, Y Newhouse, P Krishnan, K Cheung, ...
Journal of Molecular Biology 421 (4), 587-600, 2012
692012
Phase Ib Study of Tirabrutinib in Combination with Idelalisib or Entospletinib in Previously Treated Chronic Lymphocytic LeukemiaPhase Ib Study of Tirabrutinib Combinations in CLL
AV Danilov, C Herbaux, HS Walter, P Hillmen, SA Rule, EA Kio, L Karlin, ...
Clinical Cancer Research 26 (12), 2810-2818, 2020
592020
Long-term follow-up of patients with CLL treated with the selective Bruton’s tyrosine kinase inhibitor ONO/GS-4059
HS Walter, S Jayne, SA Rule, G Cartron, F Morschhauser, S Macip, ...
Blood 129 (20), 2808-2810, 2017
592017
Phase II study of idelalisib, a selective inhibitor of PI3Kδ, for relapsed/refractory classical Hodgkin lymphoma
AK Gopal, MA Fanale, CH Moskowitz, AR Shustov, S Mitra, W Ye, ...
Annals of Oncology 28 (5), 1057-1063, 2017
532017
Protein turnover and inclusion body formation
S Mitra, AS Tsvetkov, S Finkbeiner
Autophagy 5 (7), 1037-1038, 2009
432009
FIGHT: A randomized, double-blind, placebo-controlled, phase II study of bemarituzumab (bema) combined with modified FOLFOX6 in 1L FGFR2b+ advanced gastric/gastroesophageal …
DVT Catenacci, YK Kang, A Saeed, K Yamaguchi, S Qin, KW Lee, IH Kim, ...
Journal of Clinical Oncology 39 (15_suppl), 4010-4010, 2021
322021
Protein turnover differences between neurons and other cells
AS Tsvetkov, S Mitra, S Finkbeiner
Autophagy 5 (7), 1037, 2009
302009
Phase I results from the phase 1/3 FIGHT study evaluating bemarituzumab and mFOLFOX6 in advanced gastric/GEJ cancer (GC)
MA Tejani, E Cheung, PD Eisenberg, AJ Scott, AA Tesfaye, L Dreiling, ...
J Clin Oncol 37 (4), 91, 2019
142019
Updated Results on the Clinical Activity of Entospletinib (GS-9973), a Selective Syk Inhibitor, in Patients with CLL Previously Treated with an Inhibitor of the B-Cell Receptor …
JP Sharman, AR Shustov, MR Smith, CT Hagenstad, KS Kolibaba, ...
Blood 128 (22), 3225-3225, 2016
92016
Clinical activity of entospletinib (GS-9973), a selective SYK inhibitor, in patients with CLL previously treated with an inhibitor of B-cell receptor pathway signaling
JP Sharman, AR Shustov, MR Smith, TE Boyd, C Hagenstad, KS Kolibaba, ...
Blood 126 (23), 1744-1744, 2015
32015
Long-Term Follow-up with GS-4059, a Selective Irreversible BTK Inhibitor, in Patients with Relapsed and Refractory Chronic Lymphocytic Leukemia
HS Walter, S Jayne, SA Rule, G Cartron, F Morschhauser, C Fegan, ...
Blood 128 (22), 3233-3233, 2016
22016
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