Discovery of widespread type I and type V CRISPR-Cas inhibitors ND Marino, JY Zhang, AL Borges, AA Sousa, LM Leon, BJ Rauch, ... Science 362 (6411), 240-242, 2018 | 244 | 2018 |
Anti-CRISPR protein applications: natural brakes for CRISPR-Cas technologies ND Marino, R Pinilla-Redondo, B Csörgő, J Bondy-Denomy Nature methods 17 (5), 471-479, 2020 | 207 | 2020 |
A Novel Secreted Protein, MYR1, Is Central to Toxoplasma’s Manipulation of Host Cells M Franco, MW Panas, ND Marino, MCW Lee, KR Buchholz, FD Kelly, ... MBio 7 (1), 10.1128/mbio. 02231-15, 2016 | 150 | 2016 |
An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell MJ Coffey, BE Sleebs, AD Uboldi, A Garnham, M Franco, ND Marino, ... Elife 4, e10809, 2015 | 117 | 2015 |
Discovery of multiple anti-CRISPRs highlights anti-defense gene clustering in mobile genetic elements R Pinilla-Redondo, S Shehreen, ND Marino, RD Fagerlund, CM Brown, ... Nature communications 11 (1), 5652, 2020 | 108 | 2020 |
Identification of a novel protein complex essential for effector translocation across the parasitophorous vacuole membrane of Toxoplasma gondii ND Marino, MW Panas, M Franco, TC Theisen, A Naor, S Rastogi, ... PLoS pathogens 14 (1), e1006828, 2018 | 102 | 2018 |
GRA25 is a novel virulence factor of Toxoplasma gondii and influences the host immune response AJ Shastri, ND Marino, M Franco, MB Lodoen, JC Boothroyd Infection and immunity 82 (6), 2595-2605, 2014 | 79 | 2014 |
MYR1-Dependent Effectors Are the Major Drivers of a Host Cell’s Early Response to Toxoplasma, Including Counteracting MYR1-Independent Effects A Naor, MW Panas, N Marino, MJ Coffey, CJ Tonkin, JC Boothroyd MBio 9 (2), 10.1128/mbio. 02401-17, 2018 | 52 | 2018 |
Coimmunoprecipitation with MYR1 identifies three additional proteins within the Toxoplasma gondii parasitophorous vacuole required for translocation of dense granule effectors … AM Cygan, TC Theisen, AG Mendoza, ND Marino, MW Panas, ... Msphere 5 (1), 10.1128/msphere. 00858-19, 2020 | 46 | 2020 |
Toxoplasma growth in vitro is dependent on exogenous tyrosine and is independent of AAH2 even in tyrosine-limiting conditions ND Marino, JC Boothroyd Experimental parasitology 176, 52-58, 2017 | 26 | 2017 |
CRISPR-Cas12a targeting of ssDNA plays no detectable role in immunity ND Marino, R Pinilla-Redondo, J Bondy-Denomy Nucleic Acids Research 50 (11), 6414-6422, 2022 | 20 | 2022 |
A novel secreted protein, MYR1, is central to Toxoplasma’s manipulation of host cells. MBio. 2016; 7 (1): e02231–15 M Franco, MW Panas, ND Marino, MC Lee, KR Buchholz, FD Kelly, ... PubMed Abstract| Publisher Full Text| Free Full Text| F1000 Recommendation, 0 | 9 | |
Translation-dependent downregulation of Cas12a mRNA by an anti-CRISPR protein ND Marino, A Talaie, H Carion, MC Johnson, Y Zhang, S Silas, Y Li, ... BioRxiv, 2022.11. 29.518452, 2022 | 8 | 2022 |
Phage against the machine: Discovery and mechanism of type V anti-CRISPRs ND Marino Journal of Molecular Biology 435 (7), 168054, 2023 | 5 | 2023 |
Discovery of multiple anti-CRISPRs uncovers anti-defense gene clustering in mobile genetic elements R Pinilla-Redondo, S Shehreen, ND Marino, RD Fagerlund, CM Brown, ... bioRxiv, 2020.05. 22.110304, 2020 | 4 | 2020 |
Immunology: NACHT domain proteins get a prokaryotic origin story ND Marino, IE Brodsky Current Biology 33 (16), R875-R878, 2023 | | 2023 |
Dual strategies for CRISPR-Cas12 inactivation in bacteria ND Marino 5th International Conference on CRISPR Technologies, 2022 | | 2022 |