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Saghi Ghaffari
Saghi Ghaffari
Professor of CDRB and Oncological Sciences, Icahn School of Medicine at Mount Sinai
Verified email at mssm.edu - Homepage
Title
Cited by
Cited by
Year
Development of human protein reference database as an initial platform for approaching systems biology in humans
S Peri, JD Navarro, R Amanchy, TZ Kristiansen, CK Jonnalagadda, ...
Genome research 13 (10), 2363-2371, 2003
13302003
Stem cells and the impact of ROS signaling
CL Bigarella, R Liang, S Ghaffari
Development 141 (22), 4206-4218, 2014
6492014
Oxidative stress in the regulation of normal and neoplastic hematopoiesis
S Ghaffari
Antioxidants & redox signaling 10 (11), 1923-1940, 2008
4182008
Foxo3 is required for the regulation of oxidative stress in erythropoiesis
D Marinkovic, X Zhang, S Yalcin, JP Luciano, C Brugnara, T Huber, ...
The Journal of clinical investigation 117 (8), 2133-2144, 2007
3642007
FOXO1 is an essential regulator of pluripotency in human embryonic stem cells
X Zhang, S Yalcin, DF Lee, TYJ Yeh, SM Lee, J Su, SK Mungamuri, ...
Nature cell biology 13 (9), 1092-1099, 2011
2942011
The erythropoietin receptor: structure, activation and intracellular signal transduction
SN Constantinescu, S Ghaffari, HF Lodish
Trends in Endocrinology & Metabolism 10 (1), 18-23, 1999
2911999
Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells
S Yalcin, X Zhang, JP Luciano, SK Mungamuri, D Marinkovic, C Vercherat, ...
Journal of Biological Chemistry 283 (37), 25692-25705, 2008
2742008
Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia
P Ramos, C Casu, S Gardenghi, L Breda, BJ Crielaard, E Guy, ...
Nature medicine 19 (4), 437-445, 2013
2492013
miR-451 protects against erythroid oxidant stress by repressing 14-3-3ζ
D Yu, CO dos Santos, G Zhao, J Jiang, JD Amigo, E Khandros, LC Dore, ...
Genes & development 24 (15), 1620-1633, 2010
2462010
Erythropoietin stimulates phosphorylation and activation of GATA-1 via the PI3-kinase/AKT signaling pathway
W Zhao, C Kitidis, MD Fleming, HF Lodish, S Ghaffari
Blood 107 (3), 907-915, 2006
2352006
Oxidative stress regulation of stem and progenitor cells
S Pervaiz, R Taneja, S Ghaffari
Antioxidants & redox signaling 11 (11), 2777-2789, 2009
2072009
Structure of the Bcr-Abl oncoprotein oligomerization domain
X Zhao, S Ghaffari, H Lodish, VN Malashkevich, PS Kim
Nature structural biology 9 (2), 117-120, 2002
1952002
Cytokines and BCR-ABL mediate suppression of TRAIL-induced apoptosis through inhibition of forkhead FOXO3a transcription factor
S Ghaffari, Z Jagani, C Kitidis, HF Lodish, R Khosravi-Far
Proceedings of the National Academy of Sciences 100 (11), 6523-6528, 2003
1822003
Restraining lysosomal activity preserves hematopoietic stem cell quiescence and potency
R Liang, T Arif, S Kalmykova, A Kasianov, M Lin, V Menon, J Qiu, ...
Cell stem cell 26 (3), 359-376. e7, 2020
1782020
Aging-like phenotype and defective lineage specification in SIRT1-deleted hematopoietic stem and progenitor cells
P Rimmelé, CL Bigarella, R Liang, B Izac, R Dieguez-Gonzalez, G Barbet, ...
Stem cell reports 3 (1), 44-59, 2014
1652014
ROS‐mediated amplification of AKT/mTOR signalling pathway leads to myeloproliferative syndrome in Foxo3−/− mice
S Yalcin, D Marinkovic, SK Mungamuri, X Zhang, W Tong, R Sellers, ...
The EMBO journal 29 (24), 4118-4131, 2010
1612010
CDKN1A regulates Langerhans cell survival and promotes Treg cell generation upon exposure to ionizing irradiation
JG Price, J Idoyaga, H Salmon, B Hogstad, CL Bigarella, S Ghaffari, ...
Nature immunology 16 (10), 1060-1068, 2015
1322015
Mitochondria in the maintenance of hematopoietic stem cells: new perspectives and opportunities
MD Filippi, S Ghaffari
Blood, The Journal of the American Society of Hematology 133 (18), 1943-1952, 2019
1242019
Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO 3
P Rimmelé, R Liang, CL Bigarella, F Kocabas, J Xie, MN Serasinghe, ...
EMBO reports 16 (9), 1164-1176, 2015
1192015
Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice
SS Franco, L De Falco, S Ghaffari, C Brugnara, DA Sinclair, A Iolascon, ...
haematologica 99 (2), 267, 2014
1162014
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