Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication F Christ, A Voet, A Marchand, S Nicolet, BA Desimmie, D Marchand, ... Nature chemical biology 6 (6), 442-448, 2010 | 537 | 2010 |
Multiple APOBEC3 restriction factors for HIV-1 and one Vif to rule them all BA Desimmie, KA Delviks-Frankenberrry, RC Burdick, DF Qi, T Izumi, ... Journal of molecular biology 426 (6), 1220-1245, 2014 | 236 | 2014 |
Small-molecule inhibitors of the LEDGF/p75 binding site of integrase block HIV replication and modulate integrase multimerization F Christ, S Shaw, J Demeulemeester, BA Desimmie, A Marchand, S Butler, ... Antimicrobial agents and chemotherapy 56 (8), 4365-4374, 2012 | 214 | 2012 |
LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions BA Desimmie, R Schrijvers, J Demeulemeester, D Borrenberghs, ... Retrovirology 10, 1-16, 2013 | 169 | 2013 |
Alterations in serum levels of trace elements in tuberculosis and HIV infections A Kassu, T Yabutani, ZH Mahmud, A Mohammad, N Nguyen, BTM Huong, ... European journal of clinical nutrition 60 (5), 580-586, 2006 | 160 | 2006 |
Coinfection and clinical manifestations of tuberculosis in human immunodeficiency virus-infected and-uninfected adults at a teaching hospital, northwest Ethiopia A Kassu, G Mengistu, B Ayele, E Diro, F Mekonnen, D Ketema, F Moges, ... Journal of Microbiology Immunology and Infection 40 (2), 116, 2007 | 98 | 2007 |
Phage display-directed discovery of LEDGF/p75 binding cyclic peptide inhibitors of HIV replication BA Desimmie, M Humbert, E Lescrinier, J Hendrix, S Vets, R Gijsbers, ... Molecular Therapy 20 (11), 2064-2075, 2012 | 74 | 2012 |
Insights into SARS-CoV-2 persistence and its relevance BA Desimmie, YY Raru, HM Awadh, P He, S Teka, KS Willenburg Viruses 13 (6), 1025, 2021 | 60 | 2021 |
Visceral Lieshmaniasis and HIV co-infection in patients admitted to Gondar University Hospital, Northwest Ethiopia G Mengistu, B Ayele Ethiopian Journal of Health Development 21 (1), 53-60, 2007 | 52 | 2007 |
Effects of a food supplement rich in arginine in patients with smear positive pulmonary tuberculosis–a randomised trial T Schön, J Idh, A Westman, D Elias, E Abate, E Diro, F Moges, A Kassu, ... Tuberculosis 91 (5), 370-377, 2011 | 46 | 2011 |
Nitric oxide production in the exhaled air of patients with pulmonary tuberculosis in relation to HIV co-infection J Idh, A Westman, D Elias, F Moges, A Getachew, A Gelaw, T Sundqvist, ... BMC Infectious Diseases 8, 1-8, 2008 | 42 | 2008 |
HIV and intestinal parasites in adult TB patients in a teaching hospital in Northwest Ethiopia A Kassu, G Mengistu, B Ayele, E Diro, F Mekonnen, D Ketema, F Moges, ... Tropical doctor 37 (4), 222-224, 2007 | 41 | 2007 |
APOBEC3 proteins can copackage and comutate HIV-1 genomes BA Desimmie, RC Burdick, T Izumi, H Doi, W Shao, WG Alvord, K Sato, ... Nucleic acids research 44 (16), 7848-7865, 2016 | 40 | 2016 |
Cellular cofactors of lentiviral integrase: from target validation to drug discovery O Taltynov, BA Desimmie, J Demeulemeester, F Christ, Z Debyser Molecular biology international 2012, 2012 | 37 | 2012 |
2-Hydroxyisoquinoline-1,3(2H,4H)-diones (HIDs), Novel Inhibitors of HIV Integrase with a High Barrier to Resistance BA Desimmie, J Demeulemeester, V Suchaud, O Taltynov, M Billamboz, ... ACS chemical biology 8 (6), 1187-1194, 2013 | 29 | 2013 |
Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies SJ Ziegler, C Liu, M Landau, O Buzovetsky, BA Desimmie, Q Zhao, ... PLoS One 13 (3), e0195048, 2018 | 28 | 2018 |
HIV-1 IN/Pol recruits LEDGF/p75 into viral particles BA Desimmie, C Weydert, R Schrijvers, S Vets, J Demeulemeester, ... Retrovirology 12, 1-15, 2015 | 28 | 2015 |
Structural insights into APOBEC3-mediated lentiviral restriction KA Delviks-Frankenberry, BA Desimmie, VK Pathak Viruses 12 (6), 587, 2020 | 27 | 2020 |
Structural basis of antagonism of human APOBEC3F by HIV-1 Vif Y Hu, BA Desimmie, HC Nguyen, SJ Ziegler, TC Cheng, J Chen, J Wang, ... Nature structural & molecular biology 26 (12), 1176-1183, 2019 | 27 | 2019 |
Rilpivirine: a step forward in tailored HIV treatment R Schrijvers, BA Desimmie, Z Debyser The Lancet 378 (9787), 201-203, 2011 | 25 | 2011 |