‪Dr. Attila Ambrus, Ph.D., D.Sc.‬

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Danzhou YangPurdue UniversityVerified email at purdue.edu
Laszlo TretterProfessor of Biochemistry, Semmelweis UniversityVerified email at med.semmelweis-univ.hu
Frank JordanRutgers Board of Governors Professor of Chemistry, Rutgers UniversityVerified email at newark.rutgers.edu
Beata TorocsikSemmelweis University, Dept. of Medical BiochemistryVerified email at med.semmelweis-univ.hu
Oliver OzohanicsSemmelweis UniversityVerified email at semmelweis.hu
Natalia S. Nemeriaassistant research professor, Rutgers UniversityVerified email at newark.rutgers.edu
Réka MizseiNuclear Dynamics and Cancer Program, Fox Chase Cancer CenterVerified email at fccc.edu
Gergo HorvathSemmelweis University, Department of Medical BiochemistryVerified email at med.semmelweis-univ.hu
William FureyUniversity of PittsburghVerified email at pitt.edu
Christos ChinopoulosAssociate Professor, Department of Medical Biochemistry Semmelweis UniversityVerified email at med.semmelweis-univ.hu
Junjie WangPostdoctoral Associate, The Rockefeller UniversityVerified email at rockefeller.edu
Christopher RensingDistinguished Professor Fujian Agriculture and Forestry UniversityVerified email at fafu.edu.cn
Eszter SzabóSemmelweis UniversityVerified email at med.semmelweis-univ.hu
Judit DocziResearcherVerified email at med.semmelweis-univ.hu
László FésüsProfessor of Biochemistry and Molecular Biology, University of DebrecenVerified email at med.unideb.hu
Arpad SomogyiAssociate Director of CCIC Mass Spec and ProteomicsVerified email at osu.edu
Balázs GyőrffyClarivate Highly Cited, Semmelweis, PTE, HUN-REN, ELIXIR, Hungarian Academy of SciencesVerified email at ttk.mta.hu
Laurence HurleyProfessor of Medicinal Chemistry, CSO ReglageneVerified email at pharmacy.arizona.edu
László MuszbekProfessor emeritus, University of Debrecen, Research Professor, Hungarian Academy of SciencesVerified email at med.unideb.hu
István Bányaiprofessor emeritus, University of DebrecenVerified email at science.unideb.hu

Dr. Attila Ambrus, Ph.D., D.Sc.

Full Professor, Department of Biochemistry, Semmelweis University, Budapest, Hungary

Verified email at med.semmelweis-univ.hu - Homepage

protein structure and function


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Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution A Ambrus, D Chen, J Dai, T Bialis, RA Jones, D Yang Nucleic acids research 34 (9), 2723-2735, 2006	1228	2006
Solution structure of the biologically relevant G-quadruplex element in the human c-MYC promoter. Implications for G-quadruplex stabilization A Ambrus, D Chen, J Dai, RA Jones, D Yang Biochemistry 44 (6), 2048-2058, 2005	688	2005
An intramolecular G-quadruplex structure with mixed parallel/antiparallel G-strands formed in the human BCL-2 promoter region in solution J Dai, TS Dexheimer, D Chen, M Carver, A Ambrus, RA Jones, D Yang Journal of the American Chemical Society 128 (4), 1096-1098, 2006	474	2006
Structure of the intramolecular human telomeric G-quadruplex in potassium solution: a novel adenine triple formation J Dai, C Punchihewa, A Ambrus, D Chen, RA Jones, D Yang Nucleic Acids Research 35 (7), 2440-2450, 2007	430	2007
A labile regulatory copper ion lies near the T1 copper site in the multicopper oxidase CueO SA Roberts, GF Wildner, G Grass, A Weichsel, A Ambrus, C Rensing, ... Journal of Biological Chemistry 278 (34), 31958-31963, 2003	180	2003
Inhibition of the alpha‐ketoglutarate dehydrogenase‐mediated reactive oxygen species generation by lipoic acid A Ambrus, L Tretter, V Adam‐Vizi Journal of neurochemistry 109, 222-229, 2009	72	2009
Inhibition of the alpha-ketoglutarate dehydrogenase-mediated reactive oxygen species generation by lipoic acid. V Adam-Vizi, A Ambrus, L Tretter 12th Meeting of the Hungarian Neuroscience Society, doi: 10.3389/conf.neuro …, 2009	72*	2009
Inhibition of the alpha-ketoglutarate dehydrogenase-mediated reactive oxygen species generation by lipoic acid V Adam-Vizi, A Ambrus, L Tretter Frontiers in Systems Neuroscience, 136, 2009	72*	2009
Formation of reactive oxygen species by human and bacterial pyruvate and 2-oxoglutarate dehydrogenase multienzyme complexes reconstituted from recombinant components A Ambrus, NS Nemeria, B Torocsik, L Tretter, M Nilsson, F Jordan, ... Free Radical Biology and Medicine 89, 642-650, 2015	71	2015
Stimulation of reactive oxygen species generation by disease-causing mutations of lipoamide dehydrogenase A Ambrus, B Torocsik, L Tretter, O Ozohanics, V Adam-Vizi Human Molecular Genetics 20 (15), 2984-2995, 2011	69	2011
TP53 mutation hits energy metabolism and increases glycolysis in breast cancer. H Harami-Papp, LS Pongor, G Munkácsy, G Horváth, ÁM Nagy, A Ambrus, ... Oncotarget, 2016	56	2016
A direct and nondestructive approach to determine the folding structure of the I-motif DNA secondary structure by NMR J Dai, A Ambrus, LH Hurley, D Yang Journal of the American Chemical Society 131 (17), 6102-6104, 2009	54	2009
Human 2-Oxoglutarate Dehydrogenase Complex E1 Component Forms a Thiamin-derived Radical by Aerobic Oxidation of the Enamine Intermediate NS Nemeria#, A Ambrus#, H Patel#, G Gerfen, V Adam-Vizi, L Tretter, ... Journal of Biological Chemistry, jbc. M114. 591073, 2014	52	2014
Human dihydrolipoamide dehydrogenase (E3) deficiency: novel insights into the structural basis and molecular pathomechanism A Ambrus, V Adam-Vizi Neurochemistry international 117, 5-14, 2018	49	2018
Calcium binding of transglutaminases: a 43Ca NMR study combined with surface polarity analysis. A Ambrus, I Banyai, MS Weiss, R Hilgenfeld, Z Keresztessy, L Muszbek, ... Journal of biomolecular structure & dynamics 19 (1), 59, 2001	47	2001
Diffusion-ordered nuclear magnetic resonance spectroscopy for analysis of DNA secondary structural elements A Ambrus, D Yang Analytical biochemistry 367 (1), 56-67, 2007	38	2007
Molecular dynamics study of the structural basis of dysfunction and the modulation of reactive oxygen species generation by pathogenic mutants of human dihydrolipoamide … A Ambrus, V Adam-Vizi Archives of biochemistry and biophysics 538 (2), 145-155, 2013	37	2013
Hydrogen-Deuterium Exchange Mass Spectrometry: A Novel Structural Biology Approach to Structure, Dynamics and Interactions of Proteins and Their Complexes O Ozohanics, A Ambrus Life 10 (11), 286, 2020	32	2020
Membrane potential and delta pH dependency of reverse electron transport-associated hydrogen peroxide production in brain and heart mitochondria T Komlódi, FF Geibl, M Sassani, A Ambrus, L Tretter Journal of bioenergetics and biomembranes 50, 355-365, 2018	32	2018
Structural and biochemical characterization of neuronal calretinin domain I–II (residues 1–100) M Palczewska, P Groves, A Ambrus, A Kaleta, KE Kövér, G Batta, ... European Journal of Biochemistry 268 (23), 6229-6237, 2001	32	2001

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