A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells M Vedadi, D Barsyte-Lovejoy, F Liu, S Rival-Gervier, A Allali-Hassani, ... Nature chemical biology 7 (8), 566-574, 2011 | 545 | 2011 |
An orally bioavailable chemical probe of the lysine methyltransferases EZH2 and EZH1 KD Konze, A Ma, F Li, D Barsyte-Lovejoy, T Parton, CJ MacNevin, F Liu, ... ACS chemical biology 8 (6), 1324-1334, 2013 | 476 | 2013 |
Discovery of an in vivo chemical probe of the lysine methyltransferases G9a and GLP F Liu, D Barsyte-Lovejoy, F Li, Y Xiong, V Korboukh, XP Huang, ... Journal of medicinal chemistry 56 (21), 8931-8942, 2013 | 262 | 2013 |
Discovery of a 2, 4-diamino-7-aminoalkoxyquinazoline as a potent and selective inhibitor of histone lysine methyltransferase G9a F Liu, X Chen, A Allali-Hassani, AM Quinn, GA Wasney, A Dong, ... Journal of medicinal chemistry 52 (24), 7950-7953, 2009 | 244 | 2009 |
Galectin-3 deficiency reduces the severity of experimental autoimmune encephalomyelitis HR Jiang, Z Al Rasebi, E Mensah-Brown, A Shahin, D Xu, CS Goodyear, ... The Journal of Immunology 182 (2), 1167-1173, 2009 | 217 | 2009 |
Protein lysine methyltransferase G9a inhibitors: design, synthesis, and structure activity relationships of 2, 4-diamino-7-aminoalkoxy-quinazolines. F Liu, X Chen, A Allali-Hassani, AM Quinn, TJ Wigle, GA Wasney, A Dong, ... Journal of medicinal chemistry 53 (15), 5844-5857, 2010 | 216 | 2010 |
Merging [2+2] Cycloaddition with Radical 1,4‐Addition: Metal‐Free Access to Functionalized Cyclobuta[a]naphthalen‐4‐ols F Liu, JY Wang, P Zhou, G Li, WJ Hao, SJ Tu, B Jiang Angewandte Chemie International Edition 56 (49), 15570-15574, 2017 | 196 | 2017 |
Expression of TGF, matrix metalloproteinases, and tissue inhibitors in Chinese chronic rhinosinusitis X Li, J Meng, X Qiao, Y Liu, F Liu, N Zhang, J Zhang, G Holtappels, B Luo, ... Journal of Allergy and Clinical Immunology 125 (5), 1061-1068, 2010 | 166 | 2010 |
Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines F Liu, D Barsyte-Lovejoy, A Allali-Hassani, Y He, JM Herold, X Chen, ... Journal of medicinal chemistry 54 (17), 6139-6150, 2011 | 162 | 2011 |
The methyltransferase G9a regulates HoxA9-dependent transcription in AML B Lehnertz, C Pabst, L Su, M Miller, F Liu, L Yi, R Zhang, J Krosl, E Yung, ... Genes & development 28 (4), 317-327, 2014 | 156 | 2014 |
The development of nasal polyp disease involves early nasal mucosal inflammation and remodelling J Meng, P Zhou, Y Liu, F Liu, X Yi, S Liu, G Holtappels, C Bachert, ... PloS one 8 (12), e82373, 2013 | 143 | 2013 |
Dynamic pending job queue length for job distribution within a grid environment C Chen, Z Ding, Q Wang, S Yuan US Patent 9,141,432, 2015 | 127 | 2015 |
Photoredox-catalysed redox-neutral trifluoromethylation of vinyl azides for the synthesis of α-trifluoromethylated ketones HT Qin, SW Wu, JL Liu, F Liu Chemical communications 53 (10), 1696-1699, 2017 | 105 | 2017 |
An allosteric inhibitor of protein arginine methyltransferase 3 A Siarheyeva, G Senisterra, A Allali-Hassani, A Dong, E Dobrovetsky, ... Structure 20 (8), 1425-1435, 2012 | 99 | 2012 |
Selective histone deacetylase small molecule inhibitors: recent progress and perspectives HT Qin, HQ Li, F Liu Expert opinion on therapeutic patents 27 (5), 621-636, 2017 | 94 | 2017 |
Photoredox-catalysed chloro-, bromo-and trifluoromethylthio-trifluoromethylation of unactivated alkenes with sodium triflinate J Fang, ZK Wang, SW Wu, WG Shen, GZ Ao, F Liu Chemical communications 53 (54), 7638-7641, 2017 | 93 | 2017 |
Factorization approach for inclusive production of doubly heavy baryon JP Ma, ZG Si Physics Letters B 568 (1-2), 135-145, 2003 | 92 | 2003 |
Visible-light-mediated allylation of alkyl radicals with allylic sulfones via a deaminative strategy MM Zhang, F Liu Organic Chemistry Frontiers 5 (23), 3443-3446, 2018 | 86 | 2018 |
Multivariate analysis of inflammatory endotypes in recurrent nasal polyposis in a Chinese population. B Wei, F Liu, J Zhang, Y Liu, J Du, S Liu, N Zhang, C Bachert, J Meng Rhinology 56 (3), 216-226, 2018 | 78 | 2018 |
Cobalt (II)/silver relay catalytic isocyanide insertion/cycloaddition cascades: a new access to pyrrolo [2, 3-b] indoles Q Gao, P Zhou, F Liu, WJ Hao, C Yao, B Jiang, SJ Tu Chemical communications 51 (46), 9519-9522, 2015 | 78 | 2015 |