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David Porciani
David Porciani
SomaLogic; previously @University of Missouri
No verified email
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Year
A Fluorescent Split Aptamer for Visualizing RNA–RNA Assembly In Vivo
KK Alam, KD Tawiah, MF Lichte, D Porciani, DH Burke
ACS synthetic biology 6 (9), 1710-1721, 2017
1162017
Aptamer-mediated codelivery of doxorubicin and NF-κB decoy enhances chemosensitivity of pancreatic tumor cells
D Porciani, L Tedeschi, L Marchetti, L Citti, V Piazza, F Beltram, G Signore
Molecular Therapy-Nucleic Acids 4, 2015
842015
Tumor-cell–macrophage fusion cells as liquid biomarkers and tumor enhancers in cancer
Y Manjunath, D Porciani, JB Mitchem, KN Suvilesh, DM Avella, ET Kimchi, ...
International journal of molecular sciences 21 (5), 1872, 2020
632020
Aptamer-displaying peptide amphiphile micelles as a cell-targeted delivery vehicle of peptide cargoes
JD Smith, LN Cardwell, D Porciani, JA Nguyen, R Zhang, F Gallazzi, ...
Physical biology 15 (6), 065006, 2018
602018
Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines
D Porciani, LN Cardwell, KD Tawiah, KK Alam, MJ Lange, MA Daniels, ...
Nature communications 9 (1), 2283, 2018
582018
Aptamers with tunable affinity enable single‐molecule tracking and localization of membrane receptors on living cancer cells
P Delcanale, D Porciani, S Pujals, A Jurkevich, A Chetrusca, KD Tawiah, ...
Angewandte Chemie International Edition 59 (42), 18546-18555, 2020
532020
Fast-diffusing p75NTR monomers support apoptosis and growth cone collapse by neurotrophin ligands
L Marchetti, F Bonsignore, F Gobbo, R Amodeo, M Calvello, A Jacob, ...
Proceedings of the National Academy of Sciences 116 (43), 21563-21572, 2019
502019
Two interconvertible folds modulate the activity of a DNA aptamer against transferrin receptor
D Porciani, G Signore, L Marchetti, P Mereghetti, R Nifosė, F Beltram
Molecular Therapy-Nucleic Acids 3, 2014
462014
Toward the selection of cell targeting aptamers with extended biological functionalities to facilitate endosomal escape of cargoes
KD Tawiah, D Porciani, DH Burke
Biomedicines 5 (3), 51, 2017
372017
Peptide-based stealth nanoparticles for targeted and pH-triggered delivery
A Ranalli, M Santi, L Capriotti, V Voliani, D Porciani, F Beltram, G Signore
Bioconjugate Chemistry 28 (2), 627-635, 2017
292017
The minimum aptamer publication standards (MAPS guidelines) for de novo aptamer selection
M McKeague, V Calzada, L Cerchia, M DeRosa, JM Heemstra, N Janjic, ...
262022
Cancer immunomodulation using bispecific aptamers
BJ Thomas, D Porciani, DH Burke
Molecular Therapy-Nucleic Acids 27, 894-915, 2022
232022
Valency and affinity control of aptamer-conjugated nanoparticles for selective cancer cell targeting
L Woythe, D Porciani, T Harzing, S van Veen, DH Burke, L Albertazzi
Journal of Controlled Release 355, 228-237, 2023
102023
Therapeutic peptide delivery via aptamer-displaying, disulfide-linked peptide amphiphile micelles
JD Smith, LN Cardwell, D Porciani, A Nolla, BT Cornelison, MC Schulte, ...
Molecular Systems Design & Engineering 5 (1), 269-283, 2020
52020
A Nguyen
JD Smith, LN Cardwell, D Porciani
TD, Estoepangestie, AT. Chaisingh, A., Auewarakul, P., Long, HT, Hanh, NT …, 2004
52004
Lipidated poly (amino acid) nanostructures as versatile therapeutic delivery vehicles
JD Smith, LN Cardwell, D Porciani, AJ Greenwald, AC Ellis, MC Schulte, ...
bioRxiv, 2020.04. 07.004333, 2020
42020
Aptamers Targeting Hallmark Proteins of Neurodegeneration
N Mollasalehi, L Francois-Moutal, D Porciani, DH Burke, M Khanna
nucleic acid therapeutics 32 (4), 235-250, 2022
32022
Targeting lung cancer with clinically relevant EGFR mutations using anti-EGFR RNA aptamer
BJ Thomas, C Guldenpfennig, Y Guan, C Winkler, M Beecher, M Beedy, ...
Molecular Therapy-Nucleic Acids 34, 2023
12023
Anti-EGFR aptamer exhibits direct anti-cancer effects in NSCLC cells harboring EGFR L858R mutations
BJ Thomas, SZ Awan, T Joshi, MA Daniels, D Porciani, DH Burke-Aguero
bioRxiv, 2024.04. 01.587576, 2024
2024
Fluorescence Correlation Spectroscopy as a Versatile Method to Define Aptamer–Protein Interactions with Single-Molecule Sensitivity
D Porciani, MM Alampi, S Abbruzzetti, C Viappiani, P Delcanale
Analytical Chemistry 96 (1), 137-144, 2023
2023
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Articles 1–20