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Alexandria (Alex) Cogdill, MEng, PhD
Alexandria (Alex) Cogdill, MEng, PhD
Executive Director, Global Innovation, Global Business Development @ Daiichi Sankyo
Verified email at dsi.com - Homepage
Title
Cited by
Cited by
Year
Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients
V Gopalakrishnan, CN Spencer, L Nezi, A Reuben, MC Andrews, ...
Science 359 (6371), 97-103, 2018
37812018
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
CM Johannessen, JS Boehm, SY Kim, SR Thomas, L Wardwell, ...
Nature 468 (7326), 968-972, 2010
17112010
Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
LA Johnson, RA Morgan, ME Dudley, L Cassard, JC Yang, MS Hughes, ...
Blood, The Journal of the American Society of Hematology 114 (3), 535-546, 2009
17072009
B cells and tertiary lymphoid structures promote immunotherapy response
BA Helmink, SM Reddy, J Gao, S Zhang, R Basar, R Thakur, K Yizhak, ...
Nature 577 (7791), 549-555, 2020
16312020
The human tumor microbiome is composed of tumor type–specific intracellular bacteria
D Nejman, I Livyatan, G Fuks, N Gavert, Y Zwang, LT Geller, ...
Science 368 (6494), 973-980, 2020
12602020
Distinct cellular mechanisms underlie anti-CTLA-4 and anti-PD-1 checkpoint blockade
SC Wei, JH Levine, AP Cogdill, Y Zhao, NAAS Anang, MC Andrews, ...
Cell 170 (6), 1120-1133. e17, 2017
11292017
EGFR-Mediated Reactivation of MAPK Signaling Contributes to Insensitivity of BRAF-Mutant Colorectal Cancers to RAF Inhibition with Vemurafenib
RB Corcoran, H Ebi, AB Turke, EM Coffee, M Nishino, AP Cogdill, ...
Cancer discovery 2 (3), 227-235, 2012
10942012
BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma
DT Frederick, A Piris, AP Cogdill, ZA Cooper, C Lezcano, CR Ferrone, ...
Clinical cancer research 19 (5), 1225-1231, 2013
9872013
Selective BRAFV600E Inhibition Enhances T-Cell Recognition of Melanoma without Affecting Lymphocyte Function
A Boni, AP Cogdill, P Dang, D Udayakumar, CNJ Njauw, CM Sloss, ...
Cancer research 70 (13), 5213-5219, 2010
7952010
Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells
JA Fraietta, CL Nobles, MA Sammons, S Lundh, SA Carty, TJ Reich, ...
Nature 558 (7709), 307-312, 2018
6782018
Engineered CAR T cells targeting the cancer-associated Tn-glycoform of the membrane mucin MUC1 control adenocarcinoma
AD Posey, RD Schwab, AC Boesteanu, C Steentoft, U Mandel, B Engels, ...
Immunity 44 (6), 1444-1454, 2016
5722016
Affinity-tuned ErbB2 or EGFR chimeric antigen receptor T cells exhibit an increased therapeutic index against tumors in mice
X Liu, S Jiang, C Fang, S Yang, D Olalere, EC Pequignot, AP Cogdill, N Li, ...
Cancer research 75 (17), 3596-3607, 2015
5362015
Rational development and characterization of humanized anti–EGFR variant III chimeric antigen receptor T cells for glioblastoma
LA Johnson, J Scholler, T Ohkuri, A Kosaka, PR Patel, SE McGettigan, ...
Science translational medicine 7 (275), 275ra22-275ra22, 2015
4882015
Ibrutinib enhances chimeric antigen receptor T-cell engraftment and efficacy in leukemia
JA Fraietta, KA Beckwith, PR Patel, M Ruella, Z Zheng, DM Barrett, ...
Blood, The Journal of the American Society of Hematology 127 (9), 1117-1127, 2016
4812016
Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response
CN Spencer, JL McQuade, V Gopalakrishnan, JA McCulloch, M Vetizou, ...
Science 374 (6575), 1632-1640, 2021
4032021
Combination anti–CTLA-4 plus anti–PD-1 checkpoint blockade utilizes cellular mechanisms partially distinct from monotherapies
SC Wei, NAAS Anang, R Sharma, MC Andrews, A Reuben, JH Levine, ...
Proceedings of the National Academy of Sciences 116 (45), 22699-22709, 2019
2822019
Hallmarks of response to immune checkpoint blockade
AP Cogdill, MC Andrews, JA Wargo
British journal of cancer 117 (1), 1, 2017
2522017
Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment
KC Lam, RE Araya, A Huang, Q Chen, M Di Modica, RR Rodrigues, ...
Cell 184 (21), 5338-5356. e21, 2021
2472021
Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade
MC Andrews, CPM Duong, V Gopalakrishnan, V Iebba, WS Chen, ...
Nature medicine 27 (8), 1432-1441, 2021
2372021
Checkpoint blockade reverses anergy in IL-13Rα2 humanized scFv-based CAR T cells to treat murine and canine gliomas
Y Yin, AC Boesteanu, ZA Binder, C Xu, RA Reid, JL Rodriguez, DR Cook, ...
Molecular Therapy-Oncolytics 11, 20-38, 2018
1442018
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