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Ryan Hibbs
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Principles of activation and permeation in an anion-selective Cys-loop receptor
RE Hibbs, E Gouaux
Nature 474 (7349), 54-60, 2011
10832011
Structure of a human synaptic GABAA receptor
S Zhu, CM Noviello, J Teng, RM Walsh Jr, JJ Kim, RE Hibbs
Nature 559 (7712), 67-72, 2018
5052018
X-ray structure of the human α4β2 nicotinic receptor
CL Morales-Perez, CM Noviello, RE Hibbs
Nature 538 (7625), 411-415, 2016
4312016
X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors
T Althoff, RE Hibbs, S Banerjee, E Gouaux
Nature 512 (7514), 333-337, 2014
2782014
A fluorescence-detection size-exclusion chromatography-based thermostability assay for membrane protein precrystallization screening
M Hattori, RE Hibbs, E Gouaux
Structure 20 (8), 1293-1299, 2012
2592012
Shared structural mechanisms of general anaesthetics and benzodiazepines
JJ Kim, A Gharpure, J Teng, Y Zhuang, RJ Howard, S Zhu, CM Noviello, ...
Nature 585 (7824), 303-308, 2020
2332020
Structural principles of distinct assemblies of the human α4β2 nicotinic receptor
RM Walsh Jr, SH Roh, A Gharpure, CL Morales-Perez, J Teng, RE Hibbs
Nature 557 (7704), 261-265, 2018
1942018
Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore
TT Talley, M Harel, RE Hibbs, Z Radić, M Tomizawa, JE Casida, P Taylor
Proceedings of the National Academy of Sciences 105 (21), 7606-7611, 2008
1892008
Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor
RE Hibbs, G Sulzenbacher, J Shi, TT Talley, S Conrod, WR Kem, P Taylor, ...
The EMBO journal 28 (19), 3040-3051, 2009
1882009
Structure and gating mechanism of the α7 nicotinic acetylcholine receptor
CM Noviello, A Gharpure, N Mukhtasimova, R Cabuco, L Baxter, D Borek, ...
Cell 184 (8), 2121-2134. e13, 2021
1552021
Structure of the native muscle-type nicotinic receptor and inhibition by snake venom toxins
MM Rahman, J Teng, BT Worrell, CM Noviello, M Lee, A Karlin, ...
Neuron 106 (6), 952-962. e5, 2020
1482020
Agonist selectivity and ion permeation in the α3β4 ganglionic nicotinic receptor
A Gharpure, J Teng, Y Zhuang, CM Noviello, RM Walsh, R Cabuco, ...
Neuron 104 (3), 501-511. e6, 2019
1412019
Chemical and structural analysis of a photoactive vertebrate cryptochrome from pigeon
BD Zoltowski, Y Chelliah, A Wickramaratne, L Jarocha, N Karki, W Xu, ...
Proceedings of the National Academy of Sciences 116 (39), 19449-19457, 2019
1202019
Manipulation of subunit stoichiometry in heteromeric membrane proteins
CL Morales-Perez, CM Noviello, RE Hibbs
Structure 24 (5), 797-805, 2016
1022016
Direct structural insights into GABAA receptor pharmacology
JJ Kim, RE Hibbs
Trends in biochemical sciences 46 (6), 502-517, 2021
712021
Progress in nicotinic receptor structural biology
A Gharpure, CM Noviello, RE Hibbs
Neuropharmacology 171, 108086, 2020
702020
Acrylodan-conjugated cysteine side chains reveal conformational state and ligand site locations of the acetylcholine-binding protein
RE Hibbs, TT Talley, P Taylor
Journal of Biological Chemistry 279 (27), 28483-28491, 2004
682004
Structure-guided drug design: conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes
P Taylor, TT Talley, SB Hansen, RE Hibbs, J Shi
Biochemical pharmacology 74 (8), 1164-1171, 2007
612007
Influence of agonists and antagonists on the segmental motion of residues near the agonist binding pocket of the acetylcholine-binding protein
RE Hibbs, Z Radic, P Taylor, DA Johnson
Journal of biological chemistry 281 (51), 39708-39718, 2006
452006
Structural mechanism of muscle nicotinic receptor desensitization and block by curare
MM Rahman, T Basta, J Teng, M Lee, BT Worrell, MHB Stowell, RE Hibbs
Nature structural & molecular biology 29 (4), 386-394, 2022
412022
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Articles 1–20