Optimum conditions for efficient phagocytosis of rifampicin-loaded PLGA microspheres by alveolar macrophages K Hirota, T Hasegawa, H Hinata, F Ito, H Inagawa, C Kochi, GI Soma, ... Journal of controlled release 119 (1), 69-76, 2007 | 205 | 2007 |
Delivery of rifampicin–PLGA microspheres into alveolar macrophages is promising for treatment of tuberculosis K Hirota, T Hasegawa, T Nakajima, H Inagawa, C Kohchi, GI Soma, ... Journal of Controlled Release 142 (3), 339-346, 2010 | 159 | 2010 |
Preparation and properties of inhalable nanocomposite particles for treatment of lung cancer K Tomoda, T Ohkoshi, K Hirota, GS Sonavane, T Nakajima, H Terada, ... Colloids and Surfaces B: Biointerfaces 71 (2), 177-182, 2009 | 117 | 2009 |
Endocytosis of particle formulations by macrophages and its application to clinical treatment K Hirota, H Terada Molecular regulation of endocytosis 1, 2012 | 115 | 2012 |
Colloid and interface science in pharmaceutical research and development H Ohshima, K Makino Elsevier, 2014 | 100 | 2014 |
Mechanisms of in vivo release of triamcinolone acetonide from PLGA microspheres AC Doty, DG Weinstein, K Hirota, KF Olsen, R Ackermann, Y Wang, ... Journal of Controlled Release 256, 19-25, 2017 | 81 | 2017 |
Characterizing release mechanisms of leuprolide acetate-loaded PLGA microspheres for IVIVC development I: in vitro evaluation K Hirota, AC Doty, R Ackermann, J Zhou, KF Olsen, MR Feng, Y Wang, ... Journal of controlled release 244, 302-313, 2016 | 70 | 2016 |
Phagocytic activity of alveolar macrophages toward polystyrene latex microspheres and PLGA microspheres loaded with anti-tuberculosis agent T Hasegawa, K Hirota, K Tomoda, F Ito, H Inagawa, C Kochi, GI Soma, ... Colloids and Surfaces B: Biointerfaces 60 (2), 221-228, 2007 | 47 | 2007 |
Reverse engineering the 1-month Lupron Depot® J Zhou, K Hirota, R Ackermann, J Walker, Y Wang, S Choi, ... The AAPS journal 20, 1-13, 2018 | 45 | 2018 |
Distribution and deposition of respirable PLGA microspheres in lung alveoli K Hirota, T Kawamoto, T Nakajima, K Makino, H Terada Colloids and Surfaces B: Biointerfaces 105, 92-97, 2013 | 29 | 2013 |
Validation of a cage implant system for assessing in vivo performance of long-acting release microspheres AC Doty, K Hirota, KF Olsen, N Sakamoto, R Ackermann, MR Feng, ... Biomaterials 109, 88-96, 2016 | 28 | 2016 |
Phagostimulatory effect of uptake of PLGA microspheres loaded with rifampicin on alveolar macrophages K Hirota, T Hasegawa, T Nakajima, K Makino, H Terada Colloids and Surfaces B: Biointerfaces 87 (2), 293-298, 2011 | 26 | 2011 |
Features of heat-induced amorphous complex between indomethacin and lidocaine Y Shimada, S Goto, H Uchiro, H Hirabayashi, K Yamaguchi, K Hirota, ... Colloids and Surfaces B: Biointerfaces 102, 590-596, 2013 | 24* | 2013 |
Role of lipid rafts in innate immunity and phagocytosis of polystyrene latex microspheres G Nagao, K Ishii, K Hirota, K Makino, H Terada Colloids and Surfaces B: Biointerfaces 84 (2), 317-324, 2011 | 19 | 2011 |
Role of lipid rafts in phagocytic uptake of polystyrene latex microspheres by macrophages G Nagao, K Ishii, K Hirota, K Makino, H Terada Anticancer research 30 (8), 3167-3176, 2010 | 19 | 2010 |
Lipopolysaccharide-activated alveolar macrophages having cytotoxicity toward lung tumor cells through cell-to-cell binding-dependent mechanism H Taniguchi, Y Shimada, K Sawachi, K Hirota, H Inagawa, C Kohchi, ... Anticancer research 30 (8), 3159-3165, 2010 | 19 | 2010 |
Stimulation of phagocytic activity of alveolar macrophages toward artificial microspheres by infection with mycobacteria K Hirota, K Tomoda, H Inagawa, C Kohchi, GI Soma, K Makino, H Terada Pharmaceutical research 25, 1420-1430, 2008 | 19 | 2008 |
Pulmonary administration of Am80 regenerates collapsed alveoli H Sakai, M Horiguchi, C Ozawa, T Akita, K Hirota, K Shudo, H Terada, ... Journal of controlled release 196, 154-160, 2014 | 18 | 2014 |
β-Galactosidase treatment is a common first-stage modification of the three major subtypes of Gc protein to GcMAF Y Uto, S Yamamoto, H Mukai, N Ishiyama, R Takeuchi, Y Nakagawa, ... Anticancer research 32 (6), 2359-2364, 2012 | 17 | 2012 |
Exact determination of phagocytic activity of alveolar macrophages toward polymer microspheres by elimination of those attached to the macrophage membrane T Hasegawa, K Iijima, K Hirota, T Nakajima, K Makino, H Terada Colloids and Surfaces B: Biointerfaces 63 (2), 209-216, 2008 | 16 | 2008 |