Discovery of FDA-approved drugs as inhibitors of fatty acid binding protein 4 using molecular docking screening Y Wang, WK Law, JS Hu, HQ Lin, TM Ip, DCC Wan Journal of chemical information and modeling 54 (11), 3046-3050, 2014 | 46 | 2014 |
Silibinin, a novel chemokine receptor type 4 antagonist, inhibits chemokine ligand 12-induced migration in breast cancer cells Y Wang, WC Liang, WL Pan, WK Law, JS Hu, DTM Ip, MMY Waye, TB Ng, ... Phytomedicine 21 (11), 1310-1317, 2014 | 35 | 2014 |
Pimozide, a novel fatty acid binding protein 4 inhibitor, promotes adipogenesis of 3T3-L1 cells by activating PPARγ Y Wang, HQ Lin, WK Law, WC Liang, JF Zhang, JS Hu, TM Ip, MMY Waye, ... ACS chemical neuroscience 6 (2), 211-218, 2015 | 21 | 2015 |
Design, synthesis, and biological activity of a novel series of benzofuran derivatives against oestrogen receptor-dependent breast cancer cell lines LP Jin, Q Xie, EF Huang, L Wang, BQ Zhang, JS Hu, DCC Wan, Z Jin, ... Bioorganic Chemistry 95, 103566, 2020 | 15 | 2020 |
Using molecular docking screening for identifying hyperoside as an inhibitor of fatty acid binding protein 4 from a natural product database Y Wang, HQ Lin, CY Xiao, WK Law, JS Hu, TM Ip, DCC Wan Journal of functional foods 20, 159-170, 2016 | 15 | 2016 |
Synthesis and biological evaluation of indole-3-carboxamide derivatives as antioxidant agents E Huang, L Zhang, C Xiao, G Meng, B Zhang, J Hu, DCC Wan, Q Meng, ... Chinese Chemical Letters 30 (12), 2157-2159, 2019 | 11 | 2019 |
Herbalog: a tool for target-based identification of herbal drug efficacy through molecular docking Y Wang, JS Hu, HQ Lin, TM Ip, DCC Wan Phytomedicine 23 (12), 1469-1474, 2016 | 11 | 2016 |
Development of an enzyme-linked immunosorbent assay for Keap1-Nrf2 interaction inhibitors identification Y Wang, CY Xiao, HQ Lin, JS Hu, TM Ip, DCC Wan Redox Biology 34, 101573, 2020 | 10 | 2020 |
Integrated proteomics unveils nuclear PDE3A2 as a regulator of cardiac myocyte hypertrophy G Subramaniam, K Schleicher, D Kovanich, A Zerio, M Folkmanaite, ... Circulation Research 132 (7), 828-848, 2023 | 7 | 2023 |
Discovery of 4,5-Dihydro-1H-thieno[2′,3′:2,3]thiepino [4,5-c]pyrazole-3-carboxamide Derivatives as the Potential Epidermal Growth Factor Receptors for … J Ke, Q Lu, X Wang, R Sun, Z Jin, X Zhan, J Hu, DC Wan, C Hu Molecules 23 (8), 1980, 2018 | 7 | 2018 |
Discovery of a novel HIV-1 integrase/p75 interacting inhibitor by docking screening, biochemical assay, and in vitro studies Y Wang, HQ Lin, P Wang, JS Hu, TM Ip, LM Yang, YT Zheng, ... Journal of Chemical Information and Modeling 57 (9), 2336-2343, 2017 | 5 | 2017 |
Identification of 1, 4‐Dihydrothieno [3′, 2′: 5, 6] thiopyrano [4, 3‐c] pyrazole Derivatives as Human 5‐Lipo‐oxygenase Inhibitors J Hu, W Zhu, H Meng, Y Liu, X Wang, C Hu Chemical Biology & Drug Design 84 (6), 642-647, 2014 | 4 | 2014 |
The V2475F CPVT1 mutation yields distinct RyR2 channel populations that differ in their responses to cytosolic Ca2+ and Mg2+ AD Wilson, J Hu, C Sigalas, E Venturi, HH Valdivia, CR Valdivia, M Lei, ... The Journal of physiology 599 (23), 5179-5201, 2021 | 3 | 2021 |
Predicting In Vitro and In Vivo Anti-SARS-CoV-2 Activities of Antivirals by Intracellular Bioavailability and Biochemical Activity J Zhang, M He, Q Xie, A Su, K Yang, L Liu, J Liang, Z Li, X Huang, J Hu, ... ACS omega 7 (49), 45023-45035, 2022 | 2 | 2022 |
Synthesis, β-catenin Translocation Capability and ALP Activation Activity of 7H-thiazolo [3, 2-b]-1, 2, 4-triazin-7-one Derivatives S Hou, H Xu, J Hu, J Hou, Y Wang, Z Jin, DCC Wan, C Hu Medicinal Chemistry 14 (1), 67-73, 2018 | 2 | 2018 |
Biophysical characteristics of TRIC-A and TRIC-B channels and their regulation of RYR2Calcium Signaling and Excitation–Contraction in Cardiac, Skeletal and Smooth Muscle J Hu, E Venturi, C Sigalas, T Murayama, M Nishi, H Takeshima, ... Journal of General Physiology 154 (9), 2022 | 1 | 2022 |
Screening of statin analogues for effects on the activity of the cardiac ryanodine receptor C Lindsay, J Hu, A Russell, C Sigalas, RM Sitsapesan Biophysical Journal 123 (3), 103a, 2024 | | 2024 |
The biophysical properties of TRIC-A and TRIC-B and their interactions with RyR2 J Hu, E Venturi, C Sigalas, T Murayama, M Nishi, H Takeshima, ... Journal of General Physiology 155 (11), e202113070, 2023 | | 2023 |
A Homology Modelling Study of Potential RyR2 Structural Changes in R2474S and V2475F CPVT1 J Hu, RM Sitsapesan, M Musgaard Biophysical Journal 120 (3), 150a, 2021 | | 2021 |
Structure and function of trimeric intracellular cation channels (TRIC) and ryanodine receptors (RyR) J Hu University of Oxford, 2021 | | 2021 |