| MiR-193b regulates breast cancer cell migration and vasculogenic mimicry by targeting dimethylarginine dimethylaminohydrolase 1 JA Hulin, S Tommasi, D Elliot, DG Hu, BC Lewis, AA Mangoni Scientific reports 7 (1), 13996, 2017 | 71 | 2017 |
| Homoarginine and inhibition of human arginase activity: kinetic characterization and biological relevance S Tommasi, DJ Elliot, M Da Boit, SR Gray, BC Lewis, AA Mangoni Scientific reports 8 (1), 3697, 2018 | 50 | 2018 |
| Methotrexate, blood pressure and markers of arterial function in patients with rheumatoid arthritis: a repeated cross-sectional study AA Mangoni, LR Baghdadi, EM Shanahan, MD Wiese, S Tommasi, ... Therapeutic advances in musculoskeletal disease 9 (9), 213-229, 2017 | 39 | 2017 |
| Inhibition of dimethylarginine dimethylaminohydrolase (DDAH) enzymes as an emerging therapeutic strategy to target angiogenesis and vasculogenic mimicry in cancer JA Hulin, EA Gubareva, N Jarzebska, RN Rodionov, AA Mangoni, ... Frontiers in oncology 9, 1455, 2020 | 36 | 2020 |
| Inhibitors of the hydrolytic enzyme dimethylarginine dimethylaminohydrolase (DDAH): discovery, synthesis and development RB Murphy, S Tommasi, BC Lewis, AA Mangoni Molecules 21 (5), 615, 2016 | 35 | 2016 |
| One-pot ester synthesis from allyl and benzyl halides and alcohols by palladium-catalyzed carbonylation S Tommasi, S Perrone, F Rosato, A Salomone, L Troisi Synthesis 44 (03), 423-430, 2012 | 28 | 2012 |
| Small molecule inhibition of DDAH1 significantly attenuates triple negative breast cancer cell vasculogenic mimicry in vitro JA Hulin, S Tommasi, D Elliot, AA Mangoni Biomedicine & Pharmacotherapy 111, 602-612, 2019 | 27 | 2019 |
| Asymmetric dimethylarginine: a key player in the pathophysiology of endothelial dysfunction, vascular inflammation and atherosclerosis in rheumatoid arthritis? AA Mangoni, S Tommasi, S Sotgia, A Zinellu, P Paliogiannis, M Piga, ... Current Pharmaceutical Design 27 (18), 2131-2140, 2021 | 23 | 2021 |
| Repurposing existing drugs for cardiovascular risk management: a focus on methotrexate AA Mangoni, S Tommasi, A Zinellu, S Sotgia, C Carru, M Piga, GL Erre Drugs in context 7, 2018 | 19 | 2018 |
| Human dimethylarginine dimethylaminohydrolase 1 inhibition by proton pump inhibitors and the cardiovascular risk marker asymmetric dimethylarginine: in vitro and in vivo … S Tommasi, DJ Elliot, JA Hulin, BC Lewis, M McEvoy, AA Mangoni Scientific reports 7 (1), 2871, 2017 | 19 | 2017 |
| Arginine analogues incorporating carboxylate bioisosteric functions are micromolar inhibitors of human recombinant DDAH-1 S Tommasi, C Zanato, BC Lewis, PC Nair, S Dall'Angelo, M Zanda, ... Organic & Biomolecular Chemistry 13 (46), 11315-11330, 2015 | 17 | 2015 |
| Sex differences in the associations between L-arginine pathway metabolites, skeletal muscle mass and function, and their responses to resistance exercise, in old age M Da Boit, S Tommasi, D Elliot, A Zinellu, S Sotgia, R Sibson, JR Meakin, ... The Journal of nutrition, health and aging 22 (4), 534-540, 2018 | 15 | 2018 |
| The safety and exploration of the pharmacokinetics of intrapleural liposomal curcumin A Hocking, S Tommasi, P Sordillo, S Klebe International Journal of Nanomedicine, 943-952, 2020 | 11 | 2020 |
| A multicentric consortium study demonstrates that dimethylarginine dimethylaminohydrolase 2 is not a dimethylarginine dimethylaminohydrolase VN Ragavan, PC Nair, N Jarzebska, RS Angom, L Ruta, E Bianconi, ... Nature communications 14 (1), 3392, 2023 | 8 | 2023 |
| Methotrexate and vasculoprotection: mechanistic insights and potential therapeutic applications in old age AA Mangoni, S Tommasi, A Zinellu, S Sotgia, S Bassu, M Piga, GL Erre, ... Current Pharmaceutical Design 25 (39), 4175-4184, 2019 | 8 | 2019 |
| Chemical similarities and differences among inhibitors of nitric oxide synthase, arginase and dimethylarginine dimethylaminohydrolase-1: Implications for the design of novel … AJ Doman, S Tommasi, MV Perkins, RA McKinnon, AA Mangoni, PC Nair Bioorganic & Medicinal Chemistry 72, 116970, 2022 | 7 | 2022 |
| Arginine metabolites as biomarkers of myocardial ischaemia, assessed with cardiac magnetic resonance imaging in chronic kidney disease RJ Shah, S Tommasi, R Faull, JM Gleadle, AA Mangoni, ... Biomolecules 11 (3), 416, 2021 | 7 | 2021 |
| Pharmacokinetic Characterization of the DDAH1 Inhibitors ZST316 and ZST152 in Mice Using a HPLC-MS/MS Method AA Mangoni, T Ceruti, R Frapolli, M Russo, S Fichera, M Zucchetti, ... Molecules 27 (3), 1017, 2022 | 5 | 2022 |
| Development of a HPLC-MS/MS Method to Assess the Pharmacokinetics and Tumour Distribution of the Dimethylarginine Dimethylaminohydrolase 1 Inhibitors ZST316 and L-257 in a … T Ceruti, R Frapolli, C Ghilardi, A Decio, G Dellavedova, S Tommasi, ... Molecules 28 (24), 8056, 2023 | 1 | 2023 |
| Circulating arginine metabolites in Alzheimer’s disease and vascular dementia: A systematic review and meta-analysis A Zinellu, S Tommasi, S Sedda, AA Mangoni Ageing Research Reviews, 102139, 2023 | 1 | 2023 |
AA MangoniFlinders University, Adelaide, AustraliaVerified email at flinders.edu.au
