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Xiaoquan Wen
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Year
Characterization of caffeine response regulatory variants in vascular endothelial cells
C Boye, CA Kalita, AS Findley, A Alazizi, J Wei, X Wen, R Pique-Regi, ...
Elife 13, e85235, 2024
2024
Integrative analysis of the genome, transcriptome, and proteome identifies causal mechanisms of complex traits.
J Okamoto, X Yin, B Ryan, J Chiou, F Luca, R Pique-Regi, HK Im, ...
bioRxiv, 2024.03. 28.587202, 2024
2024
GWAS meta-analysis of psoriasis identifies new susceptibility alleles impacting disease mechanisms and therapeutic targets
N Dand, PE Stuart, J Bowes, D Ellinghaus, J Nititham, JR Saklatvala, ...
medRxiv, 2023
42023
Non-parametric Bayesian mixture model to study adverse events of COVID-19 vaccines
A Turfah, X Wen, L Zhao
arXiv preprint arXiv:2306.02123, 2023
2023
Genetic control of the dynamic transcriptional response to immune stimuli and glucocorticoids at single-cell resolution
JA Resztak, J Wei, S Zilioli, E Sendler, A Alazizi, HE Mair-Meijers, P Wu, ...
Genome Research 33 (6), 839-856, 2023
92023
JUMP: replicability analysis of high-throughput experiments with applications to spatial transcriptomic studies
P Lyu, Y Li, X Wen, H Cao
Bioinformatics 39 (6), btad366, 2023
22023
Imperfect gold standard gene sets yield inaccurate evaluation of causal gene identification methods
L Wang, X Wen, J Morrison
bioRxiv, 2023.05. 04.539407, 2023
2023
Mapping genomic regulation of kidney disease and traits through high-resolution and interpretable eQTLs
SK Han, MT McNulty, CJ Benway, P Wen, A Greenberg, ...
Nature Communications 14 (1), 2229, 2023
82023
Analysis of transcriptional changes in the immune system associated with pubertal development in a longitudinal cohort of children with asthma
JA Resztak, J Choe, S Nirmalan, J Wei, J Bruinsma, R Houpt, A Alazizi, ...
Nature Communications 14 (1), 230, 2023
32023
Probabilistic integration of transcriptome-wide association studies and colocalization analysis identifies key molecular pathways of complex traits
J Okamoto, L Wang, X Yin, F Luca, R Pique-Regi, A Helms, HK Im, ...
The American Journal of Human Genetics 110 (1), 44-57, 2023
62023
Functional characterization of eQTLs and asthma risk loci with scATAC-seq across immune cell types and contexts
J Wei, JA Resztak, A Alazizi, HE Mair-Meijers, RB Slatcher, S Zilioli, ...
bioRxiv, 2023.12. 24.573260, 2023
2023
A powerful replicability analysis of genome-wide association studies
Y Li, H Lei, X Wen, H Cao
medRxiv, 2023.09. 04.23295018, 2023
2023
Metabolome-wide Mendelian randomization characterizes heterogeneous and shared causal effects of metabolites on human health
X Yin, J Li, D Bose, J Okamoto, A Kwon, AU Jackson, LF Silva, ...
medRxiv, 2023.06. 26.23291721, 2023
12023
Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk
X Yin, D Bose, A Kwon, SC Hanks, AU Jackson, HM Stringham, R Welch, ...
The American Journal of Human Genetics 109 (10), 1727-1741, 2022
222022
Analyzing and reconciling colocalization and transcriptome-wide association studies from the perspective of inferential reproducibility
A Hukku, MG Sampson, F Luca, R Pique-Regi, X Wen
The American Journal of Human Genetics 109 (5), 825-837, 2022
182022
Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci
X Yin, LS Chan, D Bose, AU Jackson, P VandeHaar, AE Locke, ...
Nature communications 13 (1), 1644, 2022
762022
Exploiting the GTEx resources to decipher the mechanisms at GWAS loci
AN Barbeira, R Bonazzola, ER Gamazon, Y Liang, YS Park, ...
Genome biology 22 (1), 1-24, 2021
2012021
Analysis of transcriptional changes associated with pubertal development
J Resztak, J Choe, J Wei, R Bruinsma, R Houpt, A Alazizi, ...
bioRxiv, 2021.11. 24.469939, 2021
2021
Interspecies variation in hominid gut microbiota controls host gene regulation
AL Muehlbauer, AL Richards, A Alazizi, MB Burns, A Gomez, JB Clayton, ...
Cell reports 37 (8), 2021
112021
Genome-wide association study of 1,391 plasma metabolites in 6,136 Finnish men identifies 303 novel signals and provides biological insights into human diseases
X Yin, LS Chan, D Bose, AU Jackson, P VandeHaar, AE Locke, ...
medRxiv, 2021.10. 19.21265094, 2021
22021
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