| Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer G Van Haaften, GL Dalgliesh, H Davies, L Chen, G Bignell, C Greenman, ... Nature genetics 41 (5), 521-523, 2009 | 925 | 2009 |
| Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation EAA Nollen, SM Garcia, G Van Haaften, S Kim, A Chavez, RI Morimoto, ... Proceedings of the National Academy of Sciences 101 (17), 6403-6408, 2004 | 502 | 2004 |
| The poly (A)-binding protein nuclear 1 suppresses alternative cleavage and polyadenylation sites M Jenal, R Elkon, F Loayza-Puch, G van Haaften, U Kühn, FM Menzies, ... Cell 149 (3), 538-553, 2012 | 388 | 2012 |
| Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi J Pothof, G van Haaften, K Thijssen, RS Kamath, AG Fraser, J Ahringer, ... Genes & development 17 (4), 443-448, 2003 | 279 | 2003 |
| Exogenous anandamide protects rat brain against acute neuronal injury in vivo M Van der Stelt, WB Veldhuis, GW Van Haaften, F Fezza, T Bisogno, ... Journal of Neuroscience 21 (22), 8765-8771, 2001 | 221 | 2001 |
| Dominant missense mutations in ABCC9 cause Cantú syndrome M Harakalova, JJT Van Harssel, PA Terhal, S Van Lieshout, K Duran, ... Nature genetics 44 (7), 793-796, 2012 | 207 | 2012 |
| Effectiveness of whole-exome sequencing and costs of the traditional diagnostic trajectory in children with intellectual disability GR Monroe, GW Frederix, S Savelberg, TI De Vries, KJ Duran, ... Genetics in Medicine 18 (9), 949-956, 2016 | 190 | 2016 |
| Loss of syntaxin 3 causes variant microvillus inclusion disease CL Wiegerinck, AR Janecke, K Schneeberger, GF Vogel, ... Gastroenterology 147 (1), 65-68. e10, 2014 | 179 | 2014 |
| E2F mediates enhanced alternative polyadenylation in proliferation R Elkon, J Drost, G van Haaften, M Jenal, M Schrier, JAF Oude Vrielink, ... Genome biology 13, 1-15, 2012 | 174 | 2012 |
| The TWIST1 oncogene is a direct target of hypoxia-inducible factor-2α EH Gort, G Van Haaften, I Verlaan, AJ Groot, RHA Plasterk, A Shvarts, ... Oncogene 27 (11), 1501-1510, 2008 | 172 | 2008 |
| Phenotypic variability in patients with ADA2 deficiency due to identical homozygous R169Q mutations JM Van Montfrans, EAR Hartman, KPJ Braun, EAM Hennekam, EA Hak, ... Rheumatology 55 (5), 902-910, 2016 | 146 | 2016 |
| De novo mutations in CHD4, an ATP-dependent chromatin remodeler gene, cause an intellectual disability syndrome with distinctive dysmorphisms K Weiss, PA Terhal, L Cohen, M Bruccoleri, M Irving, AF Martinez, ... The American Journal of Human Genetics 99 (4), 934-941, 2016 | 139 | 2016 |
| LKB1/KRAS mutant lung cancers constitute a genetic subset of NSCLC with increased sensitivity to MAPK and mTOR signalling inhibition CL Mahoney, B Choudhury, H Davies, S Edkins, C Greenman, ... British journal of cancer 100 (2), 370-375, 2009 | 137 | 2009 |
| Drug repurposing for rare diseases HI Roessler, NVAM Knoers, MM van Haelst, G van Haaften Trends in pharmacological sciences 42 (4), 255-267, 2021 | 126 | 2021 |
| Loss-of-function mutations in the WNT co-receptor LRP6 cause autosomal-dominant oligodontia MPG Massink, MA Créton, F Spanevello, WMM Fennis, MS Cune, ... The American Journal of Human Genetics 97 (4), 621-626, 2015 | 120 | 2015 |
| Cantú Syndrome Resulting from Activating Mutation in the KCNJ8 Gene PE Cooper, H Reutter, J Woelfle, H Engels, DK Grange, G van Haaften, ... Human mutation 35 (7), 809-813, 2014 | 110 | 2014 |
| Identification of conserved pathways of DNA-damage response and radiation protection by genome-wide RNAi G van Haaften, R Romeijn, J Pothof, W Koole, LHF Mullenders, A Pastink, ... Current Biology 16 (13), 1344-1350, 2006 | 108 | 2006 |
| Tumorigenicity of the miR-17-92 cluster distilled G van Haaften, R Agami Genes & development 24 (1), 1-4, 2010 | 103 | 2010 |
| Further delineation of the KBG syndrome phenotype caused by ANKRD11 aberrations CW Ockeloen, MH Willemsen, S De Munnik, BW Van Bon, N De Leeuw, ... European Journal of Human Genetics 23 (9), 1176-1185, 2015 | 102* | 2015 |
| Intestinal failure and aberrant lipid metabolism in patients with DGAT1 deficiency JM van Rijn, RC Ardy, Z Kuloğlu, B Härter, DY van Haaften-Visser, ... Gastroenterology 155 (1), 130-143. e15, 2018 | 97 | 2018 |
