| Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases YNP Chen, MJ LaMarche, HM Chan, P Fekkes, J Garcia-Fortanet, ... Nature 535 (7610), 148-152, 2016 | 775 | 2016 |
| Rapid structural fluctuations of the free HIV protease flaps in solution: relationship to crystal structures and comparison with predictions of dynamics calculations DI Freedberg, R Ishima, J Jacob, YX Wang, I Kustanovich, JM Louis, ... Protein science 11 (2), 221-232, 2002 | 256 | 2002 |
| Modification of proteins in vitro by physiological levels of glucose: pyridoxamine inhibits conversion of Amadori intermediate to advanced glycation end-products through … PA Voziyan, RG Khalifah, C Thibaudeau, A Yildiz, J Jacob, AS Serianni, ... Journal of Biological Chemistry 278 (47), 46616-46624, 2003 | 192 | 2003 |
| Human Sgt1 binds HSP90 through the CHORD-Sgt1 domain and not the tetratricopeptide repeat domain YT Lee, J Jacob, W Michowski, M Nowotny, J Kuznicki, WJ Chazin Journal of Biological Chemistry 279 (16), 16511-16517, 2004 | 158 | 2004 |
| The role of proline and glycine in determining the backbone flexibility of a channel-forming peptide J Jacob, H Duclohier, DS Cafiso Biophysical journal 76 (3), 1367-1376, 1999 | 150 | 1999 |
| Measurement of 3hJNC′ connectivities across hydrogen bonds in a 30 kDa protein YX Wang, J Jacob, F Cordier, P Wingfield, SJ Stahl, S Lee-Huang, ... Journal of biomolecular NMR 14, 181-184, 1999 | 140 | 1999 |
| Solution structure of anti-HIV-1 and anti-tumor protein MAP30: structural insights into its multiple functions YX Wang, N Neamati, J Jacob, I Palmer, SJ Stahl, JD Kaufman, PL Huang, ... Cell 99 (4), 433-442, 1999 | 134 | 1999 |
| NMR assignments for a helical 40 kDa membrane protein K Oxenoid, HJ Kim, J Jacob, FD Sönnichsen, CR Sanders Journal of the American Chemical Society 126 (16), 5048-5049, 2004 | 115 | 2004 |
| Kinetics of interaction of the myristoylated alanine-rich C kinase substrate, membranes, and calmodulin A Arbuzova, J Wang, D Murray, J Jacob, DS Cafiso, S McLaughlin Journal of Biological Chemistry 272 (43), 27167-27177, 1997 | 106 | 1997 |
| Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90 A Gopalsamy, M Shi, J Golas, E Vogan, J Jacob, M Johnson, F Lee, ... Journal of medicinal chemistry 51 (3), 373-375, 2008 | 105 | 2008 |
| Structural basis for the immunogenic properties of the meningococcal vaccine candidate LP2086 A Mascioni, BE Bentley, R Camarda, DA Dilts, P Fink, V Gusarova, ... Journal of biological chemistry 284 (13), 8738-8746, 2009 | 90 | 2009 |
| Interactions controlling the membrane binding of basic protein domains: phenylalanine and the attachment of the myristoylated alanine-rich C-kinase substrate protein to interfaces K Victor, J Jacob, DS Cafiso Biochemistry 38 (39), 12527-12536, 1999 | 77 | 1999 |
| Stereospecific Formation of Interstrand Carbinolamine DNA Cross-Links by Crotonaldehyde- and Acetaldehyde-Derived α-CH3-γ-OH-1,N2-Propano-2 … YJ Cho, H Wang, ID Kozekov, AJ Kurtz, J Jacob, M Voehler, J Smith, ... Chemical research in toxicology 19 (2), 195-208, 2006 | 66 | 2006 |
| Impact of the N-terminal domain of STAT3 in STAT3-dependent transcriptional activity T Hu, JE Yeh, L Pinello, J Jacob, S Chakravarthy, GC Yuan, R Chopra, ... Molecular and cellular biology, 2015 | 61 | 2015 |
| New approaches to mine-face ventilation A Wala, J Jacob, J Brown, G Huang Mining engineering 55 (3), 25-30, 2003 | 59 | 2003 |
| Anti-HIV and anti-tumor protein MAP30, a 30 kDa single-strand type-I RIP, shares similar secondary structure and β-sheet topology with the A chain of ricin, a type-II RIP YX Wang, J Jacob, PT Wingfield, I Palmer, SJ Stahl, JD Kaufman, ... Protein Science 9 (1), 138-144, 2000 | 59 | 2000 |
| Membrane protein preparation for TROSY NMR screening C Tian, MD Karra, CD Ellis, J Jacob, K Oxenoid, F Sönnichsen, ... Methods in enzymology 394, 321-334, 2005 | 49 | 2005 |
| Axonal transport of neurofilament is accelerated in peripheral nerve during 2, 5-hexanedione intoxication S Monaco, J Jacob, H Jenich, A Patton, L Autilio-Gambetti, P Gambetti Brain research 491 (2), 328-334, 1989 | 46 | 1989 |
| Identification and characterization of acidic mammalian chitinase inhibitors DC Cole, AM Olland, J Jacob, J Brooks, MG Bursavich, R Czerwinski, ... Journal of medicinal chemistry 53 (16), 6122-6128, 2010 | 45 | 2010 |
| Spectroscopic Characterization of Interstrand Carbinolamine Cross-Links Formed in the 5‘-CpG-3‘ Sequence by the Acrolein-Derived γ-OH-1,N 2-Propano-2 … YJ Cho, HY Kim, H Huang, A Slutsky, IG Minko, H Wang, LV Nechev, ... Journal of the American Chemical Society 127 (50), 17686-17696, 2005 | 44 | 2005 |
