Pyrazine derivatives: a patent review (June 2012–present) M Dolezal, J Zitko Expert opinion on therapeutic patents 25 (1), 33-47, 2015 | 94 | 2015 |
Exploring the detailed spectroscopic characteristics, chemical and biological activity of two cyanopyrazine-2-carboxamide derivatives using experimental and theoretical tools S Beegum, YS Mary, YS Mary, R Thomas, S Armaković, SJ Armaković, ... Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 224, 117414, 2020 | 70 | 2020 |
Substituted N-Phenylpyrazine-2-carboxamides: Synthesis and Antimycobacterial Evaluation M Doležal, J Zitko, D Kešetovičová, J Kuneš, M Svobodová Molecules 14 (10), 4180-4189, 2009 | 59 | 2009 |
Synthesis, Antimycobacterial, Antifungal and Photosynthesis-Inhibiting Activity of Chlorinated N-phenylpyrazine-2-carboxamides M Dolezal, J Zitko, Z Osicka, J Kunes, M Vejsova, V Buchta, J Dohnal, ... Molecules 15 (12), 8567-8581, 2010 | 56 | 2010 |
Spectroscopic, quantum chemical studies, Fukui functions, in vitro antiviral activity and molecular docking of 5-chloro-N-(3-nitrophenyl) pyrazine-2-carboxamide SHR Sebastian, MA Al-Alshaikh, AA El-Emam, CY Panicker, J Zitko, ... Journal of Molecular Structure 1119, 188-199, 2016 | 50 | 2016 |
Synthesis and antimycobacterial properties of N-substituted 6-amino-5-cyanopyrazine-2-carboxamides J Zitko, M Dolezal, M Svobodova, M Vejsova, J Kunes, R Kucera, P Jilek Bioorganic & medicinal chemistry 19 (4), 1471-1476, 2011 | 49 | 2011 |
Synthesis, Antimycobacterial Activity and In Vitro Cytotoxicity of 5-Chloro-N-phenylpyrazine-2-carboxamides J Zitko, B Servusová, P Paterová, J Mandíková, V Kubíček, R Kučera, ... Molecules 18 (12), 14807-14825, 2013 | 45 | 2013 |
Vibrational spectroscopic analysis of cyanopyrazine-2-carboxamide derivatives and investigation of their reactive properties by DFT calculations and molecular dynamics simulations S Beegum, YS Mary, HT Varghese, CY Panicker, S Armaković, ... Journal of Molecular Structure 1131, 1-15, 2017 | 43 | 2017 |
Molecular interactions of pyrazine-based compounds to proteins M Juhas, J Zitko Journal of medicinal chemistry 63 (17), 8901-8916, 2020 | 41 | 2020 |
Alkylamino derivatives of pyrazinamide: Synthesis and antimycobacterial evaluation B Servusová, P Paterová, J Mandíková, V Kubíček, R Kučera, J Kuneš, ... Bioorganic & Medicinal Chemistry Letters 24 (2), 450-453, 2014 | 36 | 2014 |
Synthesis and antimycobacterial evaluation of N-substituted 5-chloropyrazine-2-carboxamides B Servusová, J Vobicková, P Paterová, V Kubíček, J Kuneš, M Doležal, ... Bioorganic & medicinal chemistry letters 23 (12), 3589-3591, 2013 | 34 | 2013 |
Synthesis of novel pyrazinamide derivatives based on 3-chloropyrazine-2-carboxamide and their antimicrobial evaluation O Jandourek, M Tauchman, P Paterova, K Konecna, L Navratilova, ... Molecules 22 (2), 223, 2017 | 32 | 2017 |
Synthesis and antimycobacterial evaluation of 5-alkylamino-N-phenylpyrazine-2-carboxamides J Zitko, B Servusová, A Janoutová, P Paterová, J Mandíková, V Garaj, ... Bioorganic & medicinal chemistry 23 (1), 174-183, 2015 | 28 | 2015 |
Synthesis and Biological Evaluation of N-Alkyl-3-(alkylamino)-pyrazine-2-carboxamides L Semelkova, K Konecna, P Paterova, V Kubicek, J Kunes, L Novakova, ... Molecules 20 (5), 8687-8711, 2015 | 26 | 2015 |
FT-IR and FT-Raman characterization and investigation of reactive properties of N-(3-iodo-4-methylphenyl)pyrazine-2-carboxamide by molecular dynamics … PK Ranjith, ES Al-Abdullah, FAM Al-Omary, AA El-Emam, PL Anto, ... Journal of Molecular Structure 1136, 14-24, 2017 | 24 | 2017 |
Design, synthesis and antimycobacterial activity of hybrid molecules combining pyrazinamide with a 4-phenylthiazol-2-amine scaffold J Zitko, O Jand'ourek, P Paterová, L Navrátilová, J Kuneš, J Vinšová, ... Medchemcomm 9 (4), 685-696, 2018 | 23 | 2018 |
Synthesis and antimycobacterial evaluation of N-substituted 3-aminopyrazine-2, 5-dicarbonitriles J Zitko, J Jampílek, L Dobrovolný, M Svobodová, J Kuneš, M Doležal Bioorganic & medicinal chemistry letters 22 (4), 1598-1601, 2012 | 23 | 2012 |
Synthesis and antimycobacterial evaluation of pyrazinamide derivatives with benzylamino substitution J Zitko, P Paterová, V Kubíček, J Mandíková, F Trejtnar, J Kuneš, ... Bioorganic & medicinal chemistry letters 23 (2), 476-479, 2013 | 20 | 2013 |
Antimycobacterial evaluation of pyrazinoic acid reversible derivatives M Dolezal, D Kesetovic, J Zitko Current pharmaceutical design 17 (32), 3506-3514, 2011 | 20 | 2011 |
Enoyl acyl carrier protein reductase inhibitors: An updated patent review (2011–2015) J Zitko, M Doležal Expert Opinion on Therapeutic Patents 26 (9), 1079-1094, 2016 | 19 | 2016 |