Reagents and adapters for nucleic acid sequencing and methods for making such reagents and adapters SR Kennedy US Patent 11,739,367, 2023 | 4 | 2023 |
The multi-tissue landscape of somatic mtdna mutations indicates tissue specific accumulation and removal in aging M Sanchez-Contreras, MT Sweetwyne, KA Tsantilas, JA Whitson, ... eLife 12, e83395, 2023 | 18 | 2023 |
Transcript errors generate a continuous stream of amyloid and prion-like proteins in human cells C Chung, Y Kou, S Shemtov, BM Verheijen, I Flores, K Love, A del Dosso, ... bioRxiv, 2023.05. 11.540433, 2023 | 1 | 2023 |
Methods for targeted nucleic acid sequence enrichment with applications to error corrected nucleic acid sequencing SR Kennedy, M Hipp, E Schmidt, RA Risques, D Nachmanson US Patent 11,479,807, 2022 | 4 | 2022 |
Resistance of mitochondrial DNA to cadmium and Aflatoxin B1 damage-induced germline mutation accumulation in C. elegans TC Leuthner, L Benzing, BF Kohrn, CM Bergemann, MJ Hipp, ... Nucleic acids research 50 (15), 8626-8642, 2022 | 5 | 2022 |
Myometrial oxidative stress drives MED12 mutations in leiomyoma Y Li, X Xu, H Asif, Y Feng, BF Kohrn, SR Kennedy, JJ Kim, JJ Wei Cell & Bioscience 12 (1), 111, 2022 | 13 | 2022 |
RNA polymerase inaccuracy underlies SARS-CoV-2 variants and vaccine heterogeneity CC Bradley, AJE Gordon, C Wang, MB Cooke, BF Kohrn, SR Kennedy, ... Research square, 2022 | 4 | 2022 |
Probing the mechanisms of two exonuclease domain mutators of DNA polymerase ϵ JM Dahl, N Thomas, MA Tracy, BL Hearn, L Perera, SR Kennedy, AJ Herr, ... Nucleic Acids Research 50 (2), 962-974, 2022 | 7 | 2022 |
The complicated nature of somatic mtDNA mutations in aging M Sanchez-Contreras, SR Kennedy Frontiers in aging 2, 805126, 2022 | 23 | 2022 |
A replication-linked mutational gradient drives somatic mutation accumulation and influences germline polymorphisms and genome composition in mitochondrial DNA M Sanchez-Contreras, MT Sweetwyne, BF Kohrn, KA Tsantilas, MJ Hipp, ... Nucleic Acids Research 49 (19), 11103-11118, 2021 | 27 | 2021 |
PolyG-DS: An ultrasensitive polyguanine tract–profiling method to detect clonal expansions and trace cell lineage Y Zhang, BF Kohrn, M Yang, D Nachmanson, TR Soong, IH Lee, Y Tao, ... Proceedings of the National Academy of Sciences 118 (31), e2023373118, 2021 | 1 | 2021 |
Rate volatility and asymmetric segregation diversify mutation burden in cells with mutator alleles IT Dowsett, JL Sneeden, BJ Olson, J McKay-Fleisch, E McAuley, ... Communications Biology 4 (1), 21, 2021 | | 2021 |
Analyzing population structure for forensic STR markers in next generation sequencing data SE Aalbers, MJ Hipp, SR Kennedy, BS Weir Forensic Science International: Genetics 49, 102364, 2020 | 24 | 2020 |
Loss of vacuolar acidity results in iron-sulfur cluster defects and divergent homeostatic responses during aging in Saccharomyces cerevisiae KL Chen, TN Ven, MM Crane, MLC Brunner, AK Pun, KL Helget, K Brower, ... Geroscience 42, 749-764, 2020 | 22 | 2020 |
Next‐generation genotoxicology: using modern sequencing technologies to assess somatic mutagenesis and cancer risk JJ Salk, SR Kennedy Environmental and Molecular Mutagenesis 61 (1), 135-151, 2020 | 74 | 2020 |
Cancer-associated mutations but no cancer: insights into the early steps of carcinogenesis and implications for early cancer detection SR Kennedy, Y Zhang, RA Risques Trends in cancer 5 (9), 531-540, 2019 | 43 | 2019 |
Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila S Andreazza, CL Samstag, A Sanchez-Martinez, E Fernandez-Vizarra, ... Nature communications 10 (1), 3280, 2019 | 30 | 2019 |
Abnormal oxidative metabolism in a quiet genomic background underlies clear cell papillary renal cell carcinoma J Xu, E Reznik, HJ Lee, G Gundem, P Jonsson, J Sarungbam, A Bialik, ... eLife 8, e38986, 2019 | 40 | 2019 |
Mitochondrial DNA mutations are associated with ulcerative colitis preneoplasia but tend to be negatively selected in cancer KT Baker, D Nachmanson, S Kumar, MJ Emond, C Ussakli, TA Brentnall, ... Molecular Cancer Research 17 (2), 488-498, 2019 | 30 | 2019 |
Defining the impact of mutation accumulation on replicative lifespan in yeast using cancer-associated mutator phenotypes MB Lee, IT Dowsett, DT Carr, BM Wasko, SG Stanton, MS Chung, ... Proceedings of the National Academy of Sciences 116 (8), 3062-3071, 2019 | 22 | 2019 |