| Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity. G Urlaub, LA Chasin Proceedings of the National Academy of Sciences 77 (7), 4216-4220, 1980 | 1613 | 1980 |
| DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells. M Wigler, A Pellicer, S Silverstein, R Axel, G Urlaub, L Chasin Proceedings of the National Academy of Sciences 76 (3), 1373-1376, 1979 | 1547 | 1979 |
| Computational definition of sequence motifs governing constitutive exon splicing XHF Zhang, LA Chasin Genes & development 18 (11), 1241-1250, 2004 | 550 | 2004 |
| Amplified dihydrofolate reductase genes are localized to a homogeneously staining region of a single chromosome in a methotrexate-resistant Chinese hamster ovary cell line. JH Nunberg, RJ Kaufman, RT Schimke, G Urlaub, LA Chasin Proceedings of the National Academy of Sciences 75 (11), 5553-5556, 1978 | 479 | 1978 |
| Deletion of the diploid dihydrofolate reductase locus from cultured mammalian cells G Urlaub, E Käs, AM Carothers, LA Chasin Cell 33 (2), 405-412, 1983 | 437 | 1983 |
| Nonsense mutations in the dihydrofolate reductase gene affect RNA processing G Urlaub, PJ Mitchell, LA Chasin Molecular and cellular biology, 1989 | 432 | 1989 |
| Effect of gamma rays at the dihydrofolate reductase locus: deletions and inversions G Urlaub, PJ Mitchell, E Kas, LA Chasin, VL Funanage, TT Myoda, ... Somatic cell and molecular genetics 12, 555-566, 1986 | 341 | 1986 |
| Multiple splicing defects in an intronic false exon H Sun, LA Chasin Molecular and cellular biology 20 (17), 6414-6425, 2000 | 289 | 2000 |
| Quantitative evaluation of all hexamers as exonic splicing elements S Ke, S Shang, SM Kalachikov, I Morozova, L Yu, JJ Russo, J Ju, ... Genome research 21 (8), 1360-1374, 2011 | 228 | 2011 |
| Point mutation analysis in a mammalian gene: rapid preparation of total RNA, PCR amplification of cDNA, and Taq sequencing by a novel method. AM Carothers, G Urlaub, J Mucha, D Grunberger, LA Chasin BioTechniques 7 (5), 494-6, 498, 1989 | 203 | 1989 |
| Genetics of somatic mammalian cells, X. Complementation analysis of glycine-requiring mutants FT Kao, L Chasin, TT Puck Proceedings of the National Academy of Sciences 64 (4), 1284-1291, 1969 | 189 | 1969 |
| Searching for splicing motifs LA Chasin Alternative splicing in the postgenomic era, 85-106, 2007 | 180 | 2007 |
| Induction and repression of the histidine-degrading enzymes of Bacillus subtilis LA Chasin, B Magasanik Journal of Biological Chemistry 243 (19), 5165-5178, 1968 | 172 | 1968 |
| Comparison of multiple vertebrate genomes reveals the birth and evolution of human exons XHF Zhang, LA Chasin Proceedings of the National Academy of Sciences 103 (36), 13427-13432, 2006 | 170 | 2006 |
| Sequence information for the splicing of human pre-mRNA identified by support vector machine classification XHF Zhang, KA Heller, I Hefter, CS Leslie, LA Chasin Genome Research 13 (12), 2637-2650, 2003 | 170 | 2003 |
| The effect of ploidy on chemical mutagenesis in cultured Chinese hamster cells LA Chasin Journal of cellular physiology 82 (2), 299-307, 1973 | 166 | 1973 |
| Multiple transcription start sites, DNase I-hypersensitive sites, and an opposite-strand exon in the 5′ region of the CHO dhfr gene PJ Mitchell, AM Carothers, JH Han, JD Harding, E Kas, L Venolia, ... Molecular and cellular biology, 1986 | 165 | 1986 |
| Dynamic regulation of alternative splicing by silencers that modulate 5′ splice site competition Y Yu, PA Maroney, JA Denker, XHF Zhang, O Dybkov, R Lührmann, ... Cell 135 (7), 1224-1236, 2008 | 155 | 2008 |
| Human genomic sequences that inhibit splicing WG Fairbrother, LA Chasin Molecular and Cellular Biology 20 (18), 6816-6825, 2000 | 150 | 2000 |
| Gene amplification and vector engineering to achieve rapid and high-level therapeutic protein production using the Dhfr-based CHO cell selection system JJ Cacciatore, LA Chasin, EF Leonard Biotechnology advances 28 (6), 673-681, 2010 | 144 | 2010 |
