STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4 H Wang, X Huo, XR Yang, J He, L Cheng, N Wang, X Deng, H Jin, ... Molecular cancer 16, 1-15, 2017 | 475 | 2017 |
circNDUFB2 inhibits non-small cell lung cancer progression via destabilizing IGF2BPs and activating anti-tumor immunity B Li, L Zhu, C Lu, C Wang, H Wang, H Jin, X Ma, Z Cheng, C Yu, S Wang, ... Nature communications 12 (1), 295, 2021 | 342 | 2021 |
Inducing and exploiting vulnerabilities for the treatment of liver cancer C Wang, S Vegna, H Jin, B Benedict, C Lieftink, C Ramirez, ... Nature 574 (7777), 268-272, 2019 | 303 | 2019 |
circTP63 functions as a ceRNA to promote lung squamous cell carcinoma progression by upregulating FOXM1 Z Cheng, C Yu, S Cui, H Wang, H Jin, C Wang, B Li, M Qin, C Yang, J He, ... Nature communications 10 (1), 3200, 2019 | 278 | 2019 |
EGFR activation limits the response of liver cancer to lenvatinib H Jin, Y Shi, Y Lv, S Yuan, CFA Ramirez, C Lieftink, L Wang, S Wang, ... Nature 595 (7869), 730-734, 2021 | 217 | 2021 |
High-throughput functional genetic and compound screens identify targets for senescence induction in cancer L Wang, RL de Oliveira, C Wang, JMF Neto, S Mainardi, B Evers, ... Cell reports 21 (3), 773-783, 2017 | 183 | 2017 |
Evolving therapeutic landscape of advanced hepatocellular carcinoma C Yang, H Zhang, L Zhang, AX Zhu, R Bernards, W Qin, C Wang Nature reviews Gastroenterology & hepatology 20 (4), 203-222, 2023 | 156 | 2023 |
Synergistic cisplatin/doxorubicin combination chemotherapy for multidrug-resistant cancer via polymeric nanogels targeting delivery H Wu, H Jin, C Wang, Z Zhang, H Ruan, L Sun, C Yang, Y Li, W Qin, ... ACS applied materials & interfaces 9 (11), 9426-9436, 2017 | 144 | 2017 |
Metabolism‐associated molecular classification of hepatocellular carcinoma C Yang, X Huang, Z Liu, W Qin, C Wang Molecular oncology 14 (4), 896-913, 2020 | 141 | 2020 |
Gas6/Axl axis contributes to chemoresistance and metastasis in breast cancer through Akt/GSK-3β/β-catenin signaling C Wang, H Jin, N Wang, S Fan, Y Wang, Y Zhang, L Wei, X Tao, D Gu, ... Theranostics 6 (8), 1205, 2016 | 141 | 2016 |
Heat shock proteins in hepatocellular carcinoma: Molecular mechanism and therapeutic potential C Wang, Y Zhang, K Guo, N Wang, H Jin, Y Liu, W Qin International journal of cancer 138 (8), 1824-1834, 2016 | 121 | 2016 |
A powerful drug combination strategy targeting glutamine addiction for the treatment of human liver cancer H Jin, S Wang, EA Zaal, C Wang, H Wu, A Bosma, F Jochems, N Isima, ... Elife 9, e56749, 2020 | 120 | 2020 |
NANOG promotes liver cancer cell invasion by inducing epithelial–mesenchymal transition through NODAL/SMAD3 signaling pathway C Sun, L Sun, K Jiang, DM Gao, XN Kang, C Wang, S Zhang, S Huang, ... The international journal of biochemistry & cell biology 45 (6), 1099-1108, 2013 | 112 | 2013 |
A novel, liver-specific long noncoding RNA LINC01093 suppresses HCC progression by interaction with IGF2BP1 to facilitate decay of GLI1 mRNA J He, Q Zuo, BO Hu, H Jin, C Wang, Z Cheng, X Deng, C Yang, H Ruan, ... Cancer letters 450, 98-109, 2019 | 106 | 2019 |
The Cancer SENESCopedia: A delineation of cancer cell senescence F Jochems, B Thijssen, G De Conti, R Jansen, Z Pogacar, K Groot, ... Cell reports 36 (4), 2021 | 101 | 2021 |
Phospho-ERK is a biomarker of response to a synthetic lethal drug combination of sorafenib and MEK inhibition in liver cancer C Wang, H Jin, D Gao, C Lieftink, B Evers, G Jin, Z Xue, L Wang, ... Journal of hepatology 69 (5), 1057-1065, 2018 | 90 | 2018 |
Clusterin protects hepatocellular carcinoma cells from endoplasmic reticulum stress induced apoptosis through GRP78 C Wang, K Jiang, D Gao, X Kang, C Sun, Q Zhang, Y Li, L Sun, S Zhang, ... PloS one 8 (2), e55981, 2013 | 89 | 2013 |
Tumor-derived secretory clusterin induces epithelial–mesenchymal transition and facilitates hepatocellular carcinoma metastasis C Wang, K Jiang, X Kang, D Gao, C Sun, Y Li, L Sun, S Zhang, X Liu, ... The international journal of biochemistry & cell biology 44 (12), 2308-2320, 2012 | 87 | 2012 |
Hepatic stellate cells activated by acidic tumor microenvironment promote the metastasis of hepatocellular carcinoma via osteopontin J Song, Z Ge, X Yang, Q Luo, C Wang, H You, T Ge, Y Deng, H Lin, Y Cui, ... Cancer letters 356 (2), 713-720, 2015 | 80 | 2015 |
PPARγ Coactivator‐1α Suppresses Metastasis of Hepatocellular Carcinoma by Inhibiting Warburg Effect by PPARγ–Dependent WNT/β‐Catenin/Pyruvate Dehydrogenase Kinase Isozyme 1 Axis Q Zuo, J He, S Zhang, H Wang, G Jin, H Jin, Z Cheng, X Tao, C Yu, B Li, ... Hepatology 73 (2), 644-660, 2021 | 79 | 2021 |