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Nancy Hakooz
Nancy Hakooz
Professor of Pharmacogenetics-University of Jordan
Verified email at ju.edu.jo
Title
Cited by
Cited by
Year
Microsomal prediction of in vivo clearance of CYP2C9 substrates in humans
DJ Carlile, N Hakooz, MK Bayliss, JB Houston
British journal of clinical pharmacology 47 (6), 625-635, 1999
1481999
Determination of a Human Hepatic Microsomal Scaling Factor for Predicting in Vivo Drug Clearance
N Hakooz, K Ito, H Rawden, H Gill, L Lemmers, AR Boobis, RJ Edwards, ...
Pharmaceutical research 23, 533-539, 2006
802006
Prediction of metabolic clearance using cryopreserved human hepatocytes: kinetic characteristics for five benzodiazepines
D Hallifax, HC Rawden, N Hakooz, JB Houston
Drug metabolism and disposition 33 (12), 1852-1858, 2005
742005
Effects of dietary broccoli on human in vivo caffeine metabolism: a pilot study on a group of Jordanian volunteers
N Hakooz, I Hamdan
Current drug metabolism 8 (1), 9-15, 2007
722007
Allele and genotype frequencies of the polymorphic cytochrome P450 genes (CYP1A1, CYP3A4, CYP3A5, CYP2C9 and CYP2C19) in the Jordanian population
AM Yousef, NR Bulatova, W Newman, N Hakooz, S Ismail, H Qusa, ...
Molecular biology reports 39, 9423-9433, 2012
642012
Caffeine metabolic ratios for the in vivo evaluation of CYP1A2, N-acetyltransferase 2, xanthine oxidase and CYP2A6 enzymatic activities
NMK Hakooz
Current drug metabolism 10 (4), 329-338, 2009
622009
Kinetics of drug metabolism in rat liver slices: IV. Comparison of ethoxycoumarin clearance by liver slices, isolated hepatocytes, and hepatic microsomes from rats pretreated …
DJ Carlile, N Hakooz, JB Houston
Drug metabolism and disposition 27 (4), 526-532, 1999
371999
Genetic polymorphism of CYP2C19 in a Jordanian population: influence of allele frequencies of CYP2C19*1 and CYP2C19*2 on the pharmacokinetic profile of …
I Zalloum, N Hakooz, T Arafat
Molecular biology reports 39, 4195-4200, 2012
312012
Genetic analysis of thiopurine methyltransferase polymorphism in the Jordanian population
N Hakooz, T Arafat, D Payne, W Ollier, S Pushpakom, J Andrews, ...
European journal of clinical pharmacology 66, 999-1003, 2010
302010
CNV analysis associates AKNAD1 with type-2 diabetes in Jordan subpopulations
R Dajani, J Li, Z Wei, JT Glessner, X Chang, CJ Cardinale, R Pellegrino, ...
Scientific reports 5 (1), 13391, 2015
282015
Diabetes mellitus in genetically isolated populations in Jordan: prevalence, awareness, glycemic control, and associated factors
R Dajani, YS Khader, R Fatahallah, M El-Khateeb, AH Shiyab, N Hakooz
Journal of Diabetes and its Complications 26 (3), 175-180, 2012
252012
Metabolic syndrome between two ethnic minority groups (Circassians and Chechens) and the original inhabitants of Jordan
R Dajani, YS Khader, N Hakooz, R Fatahalla, F Quadan
Endocrine 43, 112-119, 2013
232013
Evaluation of novel Akt1 inhibitors as anticancer agents using virtual co-crystallized pharmacophore generation.
HN Al-Sha'er MA, Mansi I, Almazari I
J Mol Graph Model 62, 213-225, 2015
212015
Evaluation of novel Akt1 inhibitors as anticancer agents using virtual co-crystallized pharmacophore generation
MA Al-Sha’er, I Mansi, I Almazari, N Hakooz
Journal of Molecular Graphics and Modelling 62, 213-225, 2015
212015
Metformin IR versus XR pharmacokinetics in humans
N Idkaidek, T Arafat, M Melhim, J Alawneh, N Hakooz
J Bioequiv Availab 3 (10), 10.4172, 2011
212011
Effects of the genetic variants of organic cation transporters 1 and 3 on the pharmacokinetics of metformin in Jordanians.
AT Hakooz Nancy, Jarrar Yazun, Zihlif Malek, Imraish Amer, Hamed Saja
Drug Metabolism and Personalized Therapy 32 (3), 157-162, 2017
202017
SLC30A8 gene polymorphism rs13266634 associated with increased risk for developing type 2 diabetes mellitus in Jordanian population
S Mashal, M Khanfar, S Al-Khalayfa, L Srour, L Mustafa, NM Hakooz, ...
Gene 768, 145279, 2021
172021
High-performance liquid chromatographic determination of montelukast sodium in human plasma: application to bioequivalence study
AK Shakya, TA Arafat, NM Hakooz, AN Abuawwad, H Al-Hroub, M Melhim
Acta Chromatographica 26 (3), 457-472, 2014
162014
Genome-wide association study identifies novel type II diabetes risk loci in Jordan subpopulations
R Dajani, J Li, Z Wei, ME March, Q Xia, Y Khader, N Hakooz, R Fatahallah, ...
PeerJ 5, e3618, 2017
152017
UDP-glucuronosyltransferase 1A4 (UGT1A4) polymorphisms in a Jordanian population
N Hakooz, S Alzubiedi, AM Yousef, T Arafat, R Dajani, N Ababneh, ...
Molecular Biology Reports 39, 7763-7768, 2012
152012
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