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Ernesto Bernal-Mizrachi
Ernesto Bernal-Mizrachi
Professor and Chief of the Division of Endocrinology, University of Miami
Verified email at med.miami.edu
Title
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Cited by
Year
A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome)
H Inoue, Y Tanizawa, J Wasson, P Behn, K Kalidas, E Bernal-Mizrachi, ...
Nature genetics 20 (2), 143-148, 1998
8521998
Increased dosage of mammalian Sir2 in pancreatic β cells enhances glucose-stimulated insulin secretion in mice
KA Moynihan, AA Grimm, MM Plueger, E Bernal-Mizrachi, E Ford, ...
Cell metabolism 2 (2), 105-117, 2005
7972005
Islet β cell expression of constitutively active Akt1/PKBα induces striking hypertrophy, hyperplasia, and hyperinsulinemia
E Bernal-Mizrachi, W Wen, S Stahlhut, CM Welling, MA Permutt
The Journal of clinical investigation 108 (11), 1631-1638, 2001
4952001
Conditional gene targeting in mouse pancreatic β-cells: analysis of ectopic Cre transgene expression in the brain
B Wicksteed, M Brissova, W Yan, DM Opland, JL Plank, RB Reinert, ...
Diabetes 59 (12), 3090-3098, 2010
3732010
β-cell failure as a complication of diabetes
KJ Chang-Chen, R Mullur, E Bernal-Mizrachi
Reviews in Endocrine and Metabolic Disorders 9, 329-343, 2008
3402008
Defective insulin secretion and increased susceptibility to experimental diabetes are induced by reduced Akt activity in pancreatic islet β cells
E Bernal-Mizrachi, S Fatrai, JD Johnson, M Ohsugi, K Otani, Z Han, ...
The Journal of clinical investigation 114 (7), 928-936, 2004
3012004
Human β-cell proliferation and intracellular signaling: driving in the dark without a road map
RN Kulkarni, EB Mizrachi, AG Ocana, AF Stewart
Diabetes 61 (9), 2205-2213, 2012
2712012
Inhibition of Foxo1 protects pancreatic islet β-cells against fatty acid and endoplasmic reticulum stress–induced apoptosis
SC Martinez, K Tanabe, C Cras-Méneur, NA Abumrad, E Bernal-Mizrachi, ...
Diabetes 57 (4), 846-859, 2008
2712008
Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis
AC Riggs, E Bernal-Mizrachi, M Ohsugi, J Wasson, S Fatrai, C Welling, ...
Diabetologia 48, 2313-2321, 2005
2692005
Natural history of β-cell adaptation and failure in type 2 diabetes
EU Alejandro, B Gregg, M Blandino-Rosano, C Cras-Méneur, ...
Molecular aspects of medicine 42, 19-41, 2015
2592015
Akt induces β-cell proliferation by regulating cyclin D1, cyclin D2, and p21 levels and cyclin-dependent kinase-4 activity
S Fatrai, L Elghazi, N Balcazar, C Cras-Méneur, I Krits, H Kiyokawa, ...
Diabetes 55 (2), 318-325, 2006
2462006
Disruption of Tsc2 in pancreatic β cells induces β cell mass expansion and improved glucose tolerance in a TORC1-dependent manner
L Rachdi, N Balcazar, F Osorio-Duque, L Elghazi, A Weiss, A Gould, ...
Proceedings of the National Academy of Sciences 105 (27), 9250-9255, 2008
2362008
Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome
JD Johnson, E Bernal-Mizrachi, EU Alejandro, Z Han, TB Kalynyak, H Li, ...
Proceedings of the National Academy of Sciences 103 (51), 19575-19580, 2006
2332006
Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP-and Ras-dependent mechanisms
B Hegedus, B Dasgupta, JE Shin, RJ Emnett, EK Hart-Mahon, L Elghazi, ...
Cell stem cell 1 (4), 443-457, 2007
2202007
Endoplasmic reticulum stress–induced apoptosis is partly mediated by reduced insulin signaling through phosphatidylinositol 3-kinase/Akt and increased glycogen synthase kinase …
S Srinivasan, M Ohsugi, Z Liu, S Fatrai, E Bernal-Mizrachi, MA Permutt
Diabetes 54 (4), 968-975, 2005
2132005
Human β-cell proliferation and intracellular signaling part 2: still driving in the dark without a road map
E Bernal-Mizrachi, RN Kulkarni, DK Scott, F Mauvais-Jarvis, AF Stewart, ...
Diabetes 63 (3), 819-831, 2014
2032014
Interrupted glucagon signaling reveals hepatic α cell axis and role for L-glutamine in α cell proliferation
ED Dean, M Li, N Prasad, SN Wisniewski, A Von Deylen, J Spaeth, ...
Cell metabolism 25 (6), 1362-1373. e5, 2017
1722017
Human β-cell proliferation and intracellular signaling: part 3
AF Stewart, MA Hussain, A García-Ocaña, RC Vasavada, A Bhushan, ...
Diabetes 64 (6), 1872-1885, 2015
1592015
Glucose promotes pancreatic islet β-cell survival through a PI 3-kinase/Akt-signaling pathway
S Srinivasan, E Bernal-Mizrachi, M Ohsugi, MA Permutt
American Journal of Physiology-Endocrinology and Metabolism 283 (4), E784-E793, 2002
1522002
Admission hyperglycemia and radiological findings of SARS-CoV2 in patients with and without diabetes
G Iacobellis, CA Penaherrera, LE Bermudez, EB Mizrachi
Diabetes research and clinical practice 164, 108185, 2020
1472020
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