Three-dimensional retinal organoids facilitate the investigation of retinal ganglion cell development, organization and neurite outgrowth from human pluripotent stem cells CM Fligor, KB Langer, A Sridhar, Y Ren, PK Shields, MC Edler, ... Scientific reports 8 (1), 14520, 2018 | 158 | 2018 |
Retinal ganglion cell diversity and subtype specification from human pluripotent stem cells KB Langer, SK Ohlemacher, MJ Phillips, CM Fligor, P Jiang, DM Gamm, ... Stem cell reports 10 (4), 1282-1293, 2018 | 110 | 2018 |
Extension of retinofugal projections in an assembled model of human pluripotent stem cell-derived organoids CM Fligor, SS Lavekar, J Harkin, PK Shields, KB VanderWall, KC Huang, ... Stem Cell Reports 16 (9), 2228-2241, 2021 | 64 | 2021 |
Retinal ganglion cells with a glaucoma OPTN (E50K) mutation exhibit neurodegenerative phenotypes when derived from three-dimensional retinal organoids KB VanderWall, KC Huang, Y Pan, SS Lavekar, CM Fligor, AR Allsop, ... Stem Cell Reports 15 (1), 52-66, 2020 | 58 | 2020 |
Robust differentiation of mRNA-reprogrammed human induced pluripotent stem cells toward a retinal lineage A Sridhar, SK Ohlemacher, KB Langer, JS Meyer Stem cells translational medicine 5 (4), 417-426, 2016 | 52 | 2016 |
Astrocytes regulate the development and maturation of retinal ganglion cells derived from human pluripotent stem cells KB VanderWall, R Vij, SK Ohlemacher, A Sridhar, CM Fligor, EM Feder, ... Stem cell reports 12 (2), 201-212, 2019 | 40 | 2019 |
Differential susceptibility of retinal ganglion cell subtypes in acute and chronic models of injury and disease KB VanderWall, B Lu, JS Alfaro, AR Allsop, AS Carr, S Wang, JS Meyer Scientific reports 10 (1), 17359, 2020 | 38 | 2020 |
Glaucoma as a neurodegenerative disease caused by intrinsic vulnerability factors A Artero-Castro, FJ Rodriguez-Jimenez, P Jendelova, KB VanderWall, ... Progress in neurobiology 193, 101817, 2020 | 38 | 2020 |
Differentiation of retinal organoids from human pluripotent stem cells CM Fligor, KC Huang, SS Lavekar, KB VanderWall, JS Meyer Methods in Cell Biology 159, 279-302, 2020 | 36 | 2020 |
Astrocytes modulate neurodegenerative phenotypes associated with glaucoma in OPTN (E50K) human stem cell-derived retinal ganglion cells C Gomes, KB VanderWall, Y Pan, X Lu, SS Lavekar, KC Huang, ... Stem cell reports 17 (7), 1636-1649, 2022 | 18 | 2022 |
Human pluripotent stem cells as in vitro models for retinal development and disease A Sridhar, KB Langer, CM Fligor, M Steinhart, CA Miller, KT Ho-A-Lim, ... Regenerative Medicine and Stem Cell Therapy for the Eye, 17-49, 2018 | 8 | 2018 |
Differential susceptibility of rat retinal ganglion cells following optic nerve crush KB VanderWall, B Lu, S Wang, JS Meyer bioRxiv, 429282, 2018 | 4 | 2018 |
Autophagy disruption reduces mTORC1 activation leading to retinal ganglion cell neurodegeneration associated with glaucoma KC Huang, C Gomes, Y Shiga, N Belforte, KB VanderWall, SS Lavekar, ... bioRxiv, 2023 | 3 | 2023 |
Autophagy Dysfunction Represses mTORC1 Signaling Resulting in Neurodegeneration of Retinal Ganglion Cells in Glaucoma KC Huang, C Gomes, Y Shiga, K VanderWall, SS Lavekar, C Fligor, ... Investigative Ophthalmology & Visual Science 63 (7), 1475-1475, 2022 | | 2022 |
Retinal ganglion cell subtype differentiation from human pluripotent stem cells JS Meyer, KB VanderWall US Patent App. 17/534,878, 2022 | | 2022 |
GLAUCOMA PATIENT PLURIPOTENT STEM CELL-DERIVED ASTROCYTES CONTRIBUTE TO RETINAL GANGLION CELL NEURODEGENERATION C Gomes, K VanderWall, KC Huang, Y Pan, A Allsop, SS Lavekar, ... Investigative Ophthalmology & Visual Science 62 (8), 3154-3154, 2021 | | 2021 |
Alterations in mTOR Signaling Result in Glaucomatous Neurodegeneration from Human Pluripotent Stem Cell-Derived Retinal Ganglion Cells KC Huang, C Gomes, K VanderWall, S Lavekar, C Fligor, Y Pan, ... Investigative Ophthalmology & Visual Science 62 (8), 3055-3055, 2021 | | 2021 |
Modeling neurodegenerative features of glaucoma using human pluripotent stem cell-derived retinal ganglion cells SS Lavekar, C Fligor, K VanderWall, KC Huang, C Gomes, J Meyer Investigative Ophthalmology & Visual Science 62 (8), 2381-2381, 2021 | | 2021 |
Retinal ganglion cells harboring the glaucoma OPTN (E50K) mutation exhibit neurodegenerative phenotypes when derived from pluripotent stem cell-derived three-dimensional … KC Huang, K VanderWall, Y Pan, S Lavekar, C Fligor, A Allsop, K Lentsch, ... Investigative Ophthalmology & Visual Science 61 (7), 3806-3806, 2020 | | 2020 |
The Maturation of Human Pluripotent Stem Cell-Derived Retinal Ganglion Cells and Their Degeneration in Glaucoma KB VanderWall Purdue University, 2020 | | 2020 |