The enzymes of β-lactam biosynthesis RB Hamed, JR Gomez-Castellanos, L Henry, C Ducho, MA McDonough, ... Natural product reports 30 (1), 21-107, 2013 | 233 | 2013 |
Amalgamation of Nucleosides and Amino Acids in Antibiotic Biosynthesis: Discovery of an l-Threonine:Uridine-5′-Aldehyde Transaldolase S Barnard-Britson, X Chi, K Nonaka, AP Spork, N Tibrewal, A Goswami, ... Journal of the American Chemical Society 134 (45), 18514-18517, 2012 | 79 | 2012 |
Muraymycin nucleoside-peptide antibiotics: Uridine-derived natural products as lead structures for the development of novel antibacterial agents D Wiegmann, S Koppermann, M Wirth, G Niro, K Leyerer, C Ducho Beilstein journal of organic chemistry 12 (1), 769-795, 2016 | 71 | 2016 |
Lead structures for new antibacterials: stereocontrolled synthesis of a bioactive muraymycin analogue AP Spork, M Büschleb, O Ries, D Wiegmann, S Boettcher, A Mihalyi, ... Chemistry–A European Journal 20 (47), 15292-15297, 2014 | 53 | 2014 |
Discovery of a potent inhibitor class with high selectivity toward clostridial collagenases E Schönauer, AM Kany, J Haupenthal, K Hüsecken, IJ Hoppe, K Voos, ... Journal of the American Chemical Society 139 (36), 12696-12703, 2017 | 47 | 2017 |
Stereoselective synthesis of uridine-derived nucleosyl amino acids AP Spork, D Wiegmann, M Granitzka, D Stalke, C Ducho The Journal of Organic Chemistry 76 (24), 10083-10098, 2011 | 45 | 2011 |
Bis-cycloSal-d4T-monophosphates: Drugs That Deliver Two Molecules of Bioactive Nucleotides C Ducho, U Görbig, S Jessel, N Gisch, J Balzarini, C Meier Journal of medicinal chemistry 50 (6), 1335-1346, 2007 | 45 | 2007 |
Interaction of cycloSal-Pronucleotides with Cholinesterases from Different Origins. A Structure−Activity Relationship C Meier, C Ducho, U Görbig, R Esnouf, J Balzarini Journal of medicinal chemistry 47 (11), 2839-2852, 2004 | 41 | 2004 |
Efficient synthesis of the core structure of muraymycin and caprazamycin nucleoside antibiotics based on a stereochemically revised sulfur ylide reaction AP Spork, S Koppermann, B Dittrich, R Herbst-Irmer, C Ducho Tetrahedron: Asymmetry 21 (7), 763-766, 2010 | 40 | 2010 |
The biosynthesis of capuramycin-type antibiotics: Identification of the A-102395 biosynthetic gene cluster, mechanism of self-resistance, and formation of uridine-5′-carboxamide W Cai, A Goswami, Z Yang, X Liu, KD Green, S Barnard-Britson, S Baba, ... Journal of Biological Chemistry 290 (22), 13710-13724, 2015 | 37 | 2015 |
The bacterial cell envelope as delimiter of anti-infective bioavailability–An in vitro permeation model of the Gram-negative bacterial inner membrane F Graef, B Vukosavljevic, JP Michel, M Wirth, O Ries, C De Rossi, ... Journal of Controlled Release 243, 214-224, 2016 | 35 | 2016 |
Structure-based gene targeting discovery of sphaerimicin, a bacterial translocase I inhibitor. M Funabashi, S Baba, T Takatsu, M Kizuka, Y Ohata, M Tanaka, ... Angewandte Chemie International Edition 52 (44), 2013 | 35 | 2013 |
Second‐Generation cycloSal‐d4TMP Pronucleotides Bearing Esterase‐Cleavable Sites — The “Trapping” Concept C Meier, C Ducho, H Jessen, D Vukadinović‐Tenter, J Balzarini European journal of organic chemistry 2006 (1), 197-206, 2006 | 35 | 2006 |
Large expert-curated database for benchmarking document similarity detection in biomedical literature search P Brown, AC Tan, MA El-Esawi, T Liehr, O Blanck, DP Gladue, ... Database 2019, 2019 | 34 | 2019 |
Novel 5′-deoxy nucleosyl amino acid scaffolds for the synthesis of muraymycin analogues AP Spork, C Ducho Organic & biomolecular chemistry 8 (10), 2323-2326, 2010 | 33 | 2010 |
Antibacterial Muraymycins from Mutant Strains of Streptomyces sp. NRRL 30471 Z Cui, X Wang, S Koppermann, JS Thorson, C Ducho, SG Van Lanen Journal of natural products 81 (4), 942-948, 2018 | 32 | 2018 |
Pyridoxal-5′-phosphate as an oxygenase cofactor: Discovery of a carboxamide-forming, α-amino acid monooxygenase-decarboxylase Y Huang, X Liu, Z Cui, D Wiegmann, G Niro, C Ducho, Y Song, Z Yang, ... Proceedings of the National Academy of Sciences 115 (5), 974-979, 2018 | 31 | 2018 |
EPR Study into Cross‐Termination and Fragmentation with the Phenylethyl–Phenylethyl Dithiobenzoate RAFT Model System W Meiser, M Buback, O Ries, C Ducho, A Sidoruk Macromolecular Chemistry and Physics 214 (8), 924-933, 2013 | 31 | 2013 |
Crotonase catalysis enables flexible production of functionalized prolines and carbapenams RB Hamed, L Henry, JR Gomez-Castellanos, J Mecinovic, C Ducho, ... Journal of the American Chemical Society 134 (1), 471-479, 2012 | 30 | 2012 |
Pyridoxal-5′-phosphate-dependent alkyl transfer in nucleoside antibiotic biosynthesis Z Cui, J Overbay, X Wang, X Liu, Y Zhang, M Bhardwaj, A Lemke, ... Nature chemical biology 16 (8), 904-911, 2020 | 29 | 2020 |