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Christian Ducho
Christian Ducho
Verified email at uni-saarland.de - Homepage
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Year
The enzymes of β-lactam biosynthesis
RB Hamed, JR Gomez-Castellanos, L Henry, C Ducho, MA McDonough, ...
Natural product reports 30 (1), 21-107, 2013
2332013
Amalgamation of Nucleosides and Amino Acids in Antibiotic Biosynthesis: Discovery of an l-Threonine:Uridine-5′-Aldehyde Transaldolase
S Barnard-Britson, X Chi, K Nonaka, AP Spork, N Tibrewal, A Goswami, ...
Journal of the American Chemical Society 134 (45), 18514-18517, 2012
792012
Muraymycin nucleoside-peptide antibiotics: Uridine-derived natural products as lead structures for the development of novel antibacterial agents
D Wiegmann, S Koppermann, M Wirth, G Niro, K Leyerer, C Ducho
Beilstein journal of organic chemistry 12 (1), 769-795, 2016
712016
Lead structures for new antibacterials: stereocontrolled synthesis of a bioactive muraymycin analogue
AP Spork, M Büschleb, O Ries, D Wiegmann, S Boettcher, A Mihalyi, ...
Chemistry–A European Journal 20 (47), 15292-15297, 2014
532014
Discovery of a potent inhibitor class with high selectivity toward clostridial collagenases
E Schönauer, AM Kany, J Haupenthal, K Hüsecken, IJ Hoppe, K Voos, ...
Journal of the American Chemical Society 139 (36), 12696-12703, 2017
472017
Stereoselective synthesis of uridine-derived nucleosyl amino acids
AP Spork, D Wiegmann, M Granitzka, D Stalke, C Ducho
The Journal of Organic Chemistry 76 (24), 10083-10098, 2011
452011
Bis-cycloSal-d4T-monophosphates:  Drugs That Deliver Two Molecules of Bioactive Nucleotides
C Ducho, U Görbig, S Jessel, N Gisch, J Balzarini, C Meier
Journal of medicinal chemistry 50 (6), 1335-1346, 2007
452007
Interaction of cycloSal-Pronucleotides with Cholinesterases from Different Origins. A Structure−Activity Relationship
C Meier, C Ducho, U Görbig, R Esnouf, J Balzarini
Journal of medicinal chemistry 47 (11), 2839-2852, 2004
412004
Efficient synthesis of the core structure of muraymycin and caprazamycin nucleoside antibiotics based on a stereochemically revised sulfur ylide reaction
AP Spork, S Koppermann, B Dittrich, R Herbst-Irmer, C Ducho
Tetrahedron: Asymmetry 21 (7), 763-766, 2010
402010
The biosynthesis of capuramycin-type antibiotics: Identification of the A-102395 biosynthetic gene cluster, mechanism of self-resistance, and formation of uridine-5′-carboxamide
W Cai, A Goswami, Z Yang, X Liu, KD Green, S Barnard-Britson, S Baba, ...
Journal of Biological Chemistry 290 (22), 13710-13724, 2015
372015
The bacterial cell envelope as delimiter of anti-infective bioavailability–An in vitro permeation model of the Gram-negative bacterial inner membrane
F Graef, B Vukosavljevic, JP Michel, M Wirth, O Ries, C De Rossi, ...
Journal of Controlled Release 243, 214-224, 2016
352016
Structure-based gene targeting discovery of sphaerimicin, a bacterial translocase I inhibitor.
M Funabashi, S Baba, T Takatsu, M Kizuka, Y Ohata, M Tanaka, ...
Angewandte Chemie International Edition 52 (44), 2013
352013
Second‐Generation cycloSal‐d4TMP Pronucleotides Bearing Esterase‐Cleavable Sites — The “Trapping” Concept
C Meier, C Ducho, H Jessen, D Vukadinović‐Tenter, J Balzarini
European journal of organic chemistry 2006 (1), 197-206, 2006
352006
Large expert-curated database for benchmarking document similarity detection in biomedical literature search
P Brown, AC Tan, MA El-Esawi, T Liehr, O Blanck, DP Gladue, ...
Database 2019, 2019
342019
Novel 5′-deoxy nucleosyl amino acid scaffolds for the synthesis of muraymycin analogues
AP Spork, C Ducho
Organic & biomolecular chemistry 8 (10), 2323-2326, 2010
332010
Antibacterial Muraymycins from Mutant Strains of Streptomyces sp. NRRL 30471
Z Cui, X Wang, S Koppermann, JS Thorson, C Ducho, SG Van Lanen
Journal of natural products 81 (4), 942-948, 2018
322018
Pyridoxal-5′-phosphate as an oxygenase cofactor: Discovery of a carboxamide-forming, α-amino acid monooxygenase-decarboxylase
Y Huang, X Liu, Z Cui, D Wiegmann, G Niro, C Ducho, Y Song, Z Yang, ...
Proceedings of the National Academy of Sciences 115 (5), 974-979, 2018
312018
EPR Study into Cross‐Termination and Fragmentation with the Phenylethyl–Phenylethyl Dithiobenzoate RAFT Model System
W Meiser, M Buback, O Ries, C Ducho, A Sidoruk
Macromolecular Chemistry and Physics 214 (8), 924-933, 2013
312013
Crotonase catalysis enables flexible production of functionalized prolines and carbapenams
RB Hamed, L Henry, JR Gomez-Castellanos, J Mecinovic, C Ducho, ...
Journal of the American Chemical Society 134 (1), 471-479, 2012
302012
Pyridoxal-5′-phosphate-dependent alkyl transfer in nucleoside antibiotic biosynthesis
Z Cui, J Overbay, X Wang, X Liu, Y Zhang, M Bhardwaj, A Lemke, ...
Nature chemical biology 16 (8), 904-911, 2020
292020
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