| Protein splicing elements: inteins and exteins--a definition of terms and recommended nomenclature. FB Perler, EO Davis, GE Dean, FS Gimble, WE Jack, N Neff, CJ Noren, ... Nucleic acids research 22 (7), 1125, 1994 | 569 | 1994 |
| Homing of a DNA endonuclease gene by meiotic gene conversion in Saccharomyces cerevisiae FS Gimble, J Thorner Nature 357 (6376), 301-306, 1992 | 360 | 1992 |
| Crystal structure of PI-SceI, a homing endonuclease with protein splicing activity X Duan, FS Gimble, FA Quiocho Cell 89 (4), 555-564, 1997 | 357 | 1997 |
| Invasion of a multitude of genetic niches by mobile endonuclease genes FS Gimble FEMS Microbiology Letters 185 (2), 99-107, 2000 | 187 | 2000 |
| Crystal structure of the intein homing endonuclease PI-SceI bound to its recognition sequence CM Moure, FS Gimble, FA Quiocho Nature structural biology 9 (10), 764-770, 2002 | 144 | 2002 |
| Substitutions in Conserved Dodecapeptide Motifs That Uncouple the DNA Binding and DNA Cleavage Activities of PI-SceI Endonuclease (∗) FS Gimble, BW Stephens Journal of Biological Chemistry 270 (11), 5849-5856, 1995 | 133 | 1995 |
| Substrate recognition and induced DNA distortion by the PI-SceI endonuclease, an enzyme generated by protein splicing FS Gimble, J Wang Journal of molecular biology 263 (2), 163-180, 1996 | 131 | 1996 |
| The crystal structure of the gene targeting homing endonuclease I-SceI reveals the origins of its target site specificity CM Moure, FS Gimble, FA Quiocho Journal of molecular biology 334 (4), 685-695, 2003 | 130 | 2003 |
| Stimulation of intrachromosomal homologous recombination in human cells by electroporation with site-specific endonucleases. M Brenneman, FS Gimble, JH Wilson Proceedings of the National Academy of Sciences 93 (8), 3608-3612, 1996 | 98 | 1996 |
| Assessing the plasticity of DNA target site recognition of the PI-SceI homing endonuclease using a bacterial two-hybrid selection system FS Gimble, CM Moure, KL Posey Journal of molecular biology 334 (5), 993-1008, 2003 | 91 | 2003 |
| Purification and characterization of VDE, a site-specific endonuclease from the yeast Saccharomyces cerevisiae. FS Gimble, J Thorner Journal of Biological Chemistry 268 (29), 21844-21853, 1993 | 83 | 1993 |
| Engineering variants of the I-SceI homing endonuclease with strand-specific and site-specific DNA-nicking activity Y Niu, K Tenney, H Li, FS Gimble Journal of molecular biology 382 (1), 188-202, 2008 | 76 | 2008 |
| Amino acid residues in both the protein splicing and endonuclease domains of the PI-SceI intein mediate DNA binding Z He, M Crist, H Yen, X Duan, FA Quiocho, FS Gimble Journal of Biological Chemistry 273 (8), 4607-4615, 1998 | 76 | 1998 |
| λ Repressor mutants that are better substrates for RecA-mediated cleavage FS Gimble, RT Sauer Journal of molecular biology 206 (1), 29-39, 1989 | 74 | 1989 |
| λ repressor inactivation: properties of purified Ind− proteins in the autodigestion and RecA-mediated cleavage reactions FS Gimble, RT Sauer Journal of molecular biology 192 (1), 39-47, 1986 | 62 | 1986 |
| Mutations in bacteriophage lambda repressor that prevent RecA-mediated cleavage FS Gimble, RT Sauer Journal of bacteriology 162 (1), 147-154, 1985 | 58 | 1985 |
| VDE endonuclease cleaves Saccharomyces cerevisiae genomic DNA at a single site: physical mapping of the VMA1 gene. MC Bremer, FS Gimble, J Thorner, CL Smith Nucleic acids research 20 (20), 5484, 1992 | 53 | 1992 |
| Probing the structure of the PI-SceI-DNA complex by affinity cleavage and affinity photocross-linking D Hu, M Crist, X Duan, FA Quiocho, FS Gimble Journal of Biological Chemistry 275 (4), 2705-2712, 2000 | 51 | 2000 |
| Putting protein splicing to work FS Gimble Chemistry & biology 5 (10), R251-R256, 1998 | 43 | 1998 |
| Evolution of divergent DNA recognition specificities in VDE homing endonucleases from two yeast species KL Posey, V Koufopanou, A Burt, FS Gimble Nucleic acids research 32 (13), 3947-3956, 2004 | 40 | 2004 |
