| Association of γ-secretase with lipid rafts in post-Golgi and endosome membranes KS Vetrivel, H Cheng, W Lin, T Sakurai, T Li, N Nukina, PC Wong, H Xu, ... Journal of Biological Chemistry 279 (43), 44945-44954, 2004 | 528 | 2004 |
| Membrane rafts in Alzheimer's disease beta-amyloid production KS Vetrivel, G Thinakaran Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2010 | 347 | 2010 |
| Amyloidogenic processing of β-amyloid precursor protein in intracellular compartments KS Vetrivel, G Thinakaran Neurology 66 (1_suppl_1), S69-S73, 2006 | 304 | 2006 |
| Spatial segregation of γ-secretase and substrates in DistinctMembraneDomains KS Vetrivel, H Cheng, SH Kim, Y Chen, NY Barnes, AT Parent, SS Sisodia, ... Journal of Biological Chemistry 280 (27), 25892-25900, 2005 | 280 | 2005 |
| Pathological and physiological functions of presenilins KS Vetrivel, Y Zhang, H Xu, G Thinakaran Molecular neurodegeneration 1, 1-12, 2006 | 213 | 2006 |
| Alzheimer disease Aβ production in the absence of S-palmitoylation-dependent targeting of BACE1 to lipid rafts KS Vetrivel, X Meckler, Y Chen, PD Nguyen, NG Seidah, R Vassar, ... Journal of biological chemistry 284 (6), 3793-3803, 2009 | 187 | 2009 |
| Nicastrin is critical for stability and trafficking but not association of other presenilin/γ-secretase components Y Zhang, W Luo, H Wang, P Lin, KS Vetrivel, F Liao, F Li, PC Wong, ... Journal of Biological Chemistry 280 (17), 17020-17026, 2005 | 157 | 2005 |
| Mechanisms of disease: new therapeutic strategies for Alzheimer's disease—targeting APP processing in lipid rafts H Cheng, KS Vetrivel, P Gong, X Meckler, A Parent, G Thinakaran Nature Clinical Practice Neurology 3 (7), 374-382, 2007 | 124 | 2007 |
| Axonal BACE1 dynamics and targeting in hippocampal neurons: a role for Rab11 GTPase V Buggia-Prévot, CG Fernandez, S Riordan, KS Vetrivel, J Roseman, ... Molecular neurodegeneration 9, 1-18, 2014 | 105 | 2014 |
| Dual roles of the transmembrane protein p23/TMP21 in the modulation of amyloid precursor protein metabolism KS Vetrivel, P Gong, JW Bowen, H Cheng, Y Chen, M Carter, PD Nguyen, ... Molecular neurodegeneration 2, 1-12, 2007 | 103 | 2007 |
| S-palmitoylation of γ-secretase subunits nicastrin and APH-1 H Cheng, KS Vetrivel, RC Drisdel, X Meckler, P Gong, JY Leem, T Li, ... Journal of biological chemistry 284 (3), 1373-1384, 2009 | 83 | 2009 |
| A function for EHD family proteins in unidirectional retrograde dendritic transport of BACE1 and Alzheimer’s disease Aβ production V Buggia-Prevot, CG Fernandez, V Udayar, KS Vetrivel, A Elie, ... Cell reports 5 (6), 1552-1563, 2013 | 82 | 2013 |
| Evidence That CD147 Modulation of β-Amyloid (Aβ) Levels Is Mediated by Extracellular Degradation of Secreted Aβ*♦ KS Vetrivel, X Zhang, X Meckler, H Cheng, S Lee, P Gong, KO Lopes, ... Journal of biological chemistry 283 (28), 19489-19498, 2008 | 70 | 2008 |
| Altered levels and distribution of amyloid precursor protein and its processing enzymes in Niemann‐Pick type C1‐deficient mouse brains A Kodam, M Maulik, K Peake, A Amritraj, KS Vetrivel, G Thinakaran, ... Glia 58 (11), 1267-1281, 2010 | 66 | 2010 |
| Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer’s disease RJ Andrew, CG Fernandez, M Stanley, H Jiang, P Nguyen, RC Rice, ... Proceedings of the National Academy of Sciences 114 (45), E9665-E9674, 2017 | 61 | 2017 |
| Ca2+ influx through store-operated Ca2+ channels reduces Alzheimer disease β-amyloid peptide secretion W Zeiger, KS Vetrivel, V Buggia-Prévot, PD Nguyen, SL Wagner, ... Journal of Biological Chemistry 288 (37), 26955-26966, 2013 | 57 | 2013 |
| Novel GαS-protein signaling associated with membrane-tethered amyloid precursor protein intracellular domain C Deyts, KS Vetrivel, S Das, YM Shepherd, DJ Dupré, G Thinakaran, ... Journal of Neuroscience 32 (5), 1714-1729, 2012 | 57 | 2012 |
| Localization and regional distribution of p23/TMP21 in the brain KS Vetrivel, A Kodam, P Gong, Y Chen, AT Parent, S Kar, G Thinakaran Neurobiology of disease 32 (1), 37-49, 2008 | 38 | 2008 |
| Loss of cleavage at β′-site contributes to apparent increase in β-amyloid peptide (Aβ) secretion by β-secretase (BACE1)-glycosylphosphatidylinositol (GPI) processing of … KS Vetrivel, A Barman, Y Chen, PD Nguyen, SL Wagner, R Prabhakar, ... Journal of Biological Chemistry 286 (29), 26166-26177, 2011 | 35 | 2011 |
| Mutation analysis of the presenilin 1 N-terminal domain reveals a broad spectrum of γ-secretase activity toward amyloid precursor protein and other substrates P Gong, KS Vetrivel, PD Nguyen, X Meckler, H Cheng, MZ Kounnas, ... Journal of biological chemistry 285 (49), 38042-38052, 2010 | 34 | 2010 |
