Guanidinium export is the primal function of SMR family transporters AA Kermani, CB Macdonald, R Gundepudi, RB Stockbridge Proceedings of the National Academy of Sciences 115 (12), 3060-3065, 2018 | 80 | 2018 |
The structural basis of promiscuity in small multidrug resistance transporters AA Kermani, CB Macdonald, OE Burata, BB Koff, A Koide, E Denbaum, ... Nature Communications 11 (1), 1-9, 2020 | 39 | 2020 |
Antineoplastic agents. 599. Total synthesis of dolastatin 16 GR Pettit, TH Smith, PM Arce, EJ Flahive, CR Anderson, JC Chapuis, ... Journal of natural products 78 (3), 476-485, 2015 | 25 | 2015 |
A topologically diverse family of fluoride channels CB Macdonald, RB Stockbridge Current Opinion in Structural Biology 45, 142-149, 2017 | 21 | 2017 |
DIMPLE: deep insertion, deletion, and missense mutation libraries for exploring protein variation in evolution, disease, and biology CB Macdonald, D Nedrud, PR Grimes, D Trinidad, JS Fraser, ... Genome biology 24 (1), 36, 2023 | 17 | 2023 |
Still rocking in the structural era: a molecular overview of the Small Multidrug Resistance (SMR) transporter family OE Burata, TJ Yeh, CB Macdonald, RB Stockbridge Journal of Biological Chemistry 298 (10), 2022 | 11 | 2022 |
Antineoplastic agents. 600. from the south pacific ocean to the silstatins GR Pettit, PM Arce, JC Chapuis, CB Macdonald Journal of natural products 78 (3), 510-523, 2015 | 8 | 2015 |
Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain GO Estevam, EM Linossi, CB Macdonald, CA Espinoza, JM Michaud, ... bioRxiv, 2023 | 4 | 2023 |
Deep Insertion, Deletion, and Missense Mutation Libraries for Exploring Protein Variation in Evolution, Disease, and Biology CB Macdonald, D Nedrud, PR Grimes, D Trinidad, JS Fraser, ... bioRxiv, 2022.07. 26.501589, 2022 | 4 | 2022 |
The full spectrum of OCT1 (SLC22A1) mutations bridges transporter biophysics to drug pharmacogenomics SW Yee, C Macdonald, D Mitrovic, X Zhou, ML Koleske, J Yang, DB Silva, ... bioRxiv, 2023 | 3 | 2023 |
Rosace: a robust deep mutational scanning analysis framework employing position and mean-variance shrinkage J Rao, R Xin, C Macdonald, M Howard, GO Estevam, SW Yee, M Wang, ... bioRxiv, 2023.10. 24.562292, 2023 | 2 | 2023 |
DIMPLE library generation and assembly protocol C Macdonald, D Nedrud, PR Grimes, D Trinidad, C Shin, J Fraser, ... | 1 | 2023 |
Molecular basis of proton-sensing by G protein-coupled receptors MK Howard, N Hoppe, XP Huang, CB Macdonald, E Mehrotra, PR Grimes, ... bioRxiv, 2024 | | 2024 |
Studying protein variation in evolution, disease, and biology through deep insertion, deletion, and missense mutational scanning CB Macdonald Biophysical Journal 122 (3), 519a, 2023 | | 2023 |
Substrate Recognition of the Small Multidrug Resistance (SMR) Family OE Burata, CB Macdonald, AA Kermani, R Stockbridge Biophysical Journal 120 (3), 212a, 2021 | | 2021 |
Evolution of Inverted Repeats in Membrane Transporters CB Macdonald, T Cao, R Stockbridge Biophysical Journal 120 (3), 59a, 2021 | | 2021 |
Biophysical Characterization and Structural Studies of Small Multidrug Resistance Family of Transporters AA Kermani, CB Macdonald, R Stockbridge Biophysical Journal 120 (3), 70a, 2021 | | 2021 |
Overlapping Substrate Specificities in the Small Multidrug Resistance (SMR) Family of Transporters CB Macdonald, AA Kermani, RB Stockbridge Biophysical Journal 118 (3), 130a, 2020 | | 2020 |
Substrate Recognition of Guanidinium Exporters (Gdx) from the Small Multidrug Resistance (SMR) Family OE Burata, CB Macdonald, AA Kermani, R Stockbridge Biophysical Journal 118 (3), 130a, 2020 | | 2020 |
Phylogenetic and Sequence Analysis of the Flucs, a Remarkable Family of Fluoride Channels CB Macdonald, RB Stockbridge Biophysical Journal 112 (3), 255a, 2017 | | 2017 |