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Christian Macdonald, PhD
Christian Macdonald, PhD
Verified email at ucsf.edu
Title
Cited by
Cited by
Year
Guanidinium export is the primal function of SMR family transporters
AA Kermani, CB Macdonald, R Gundepudi, RB Stockbridge
Proceedings of the National Academy of Sciences 115 (12), 3060-3065, 2018
802018
The structural basis of promiscuity in small multidrug resistance transporters
AA Kermani, CB Macdonald, OE Burata, BB Koff, A Koide, E Denbaum, ...
Nature Communications 11 (1), 1-9, 2020
392020
Antineoplastic agents. 599. Total synthesis of dolastatin 16
GR Pettit, TH Smith, PM Arce, EJ Flahive, CR Anderson, JC Chapuis, ...
Journal of natural products 78 (3), 476-485, 2015
252015
A topologically diverse family of fluoride channels
CB Macdonald, RB Stockbridge
Current Opinion in Structural Biology 45, 142-149, 2017
212017
DIMPLE: deep insertion, deletion, and missense mutation libraries for exploring protein variation in evolution, disease, and biology
CB Macdonald, D Nedrud, PR Grimes, D Trinidad, JS Fraser, ...
Genome biology 24 (1), 36, 2023
172023
Still rocking in the structural era: a molecular overview of the Small Multidrug Resistance (SMR) transporter family
OE Burata, TJ Yeh, CB Macdonald, RB Stockbridge
Journal of Biological Chemistry 298 (10), 2022
112022
Antineoplastic agents. 600. from the south pacific ocean to the silstatins
GR Pettit, PM Arce, JC Chapuis, CB Macdonald
Journal of natural products 78 (3), 510-523, 2015
82015
Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain
GO Estevam, EM Linossi, CB Macdonald, CA Espinoza, JM Michaud, ...
bioRxiv, 2023
42023
Deep Insertion, Deletion, and Missense Mutation Libraries for Exploring Protein Variation in Evolution, Disease, and Biology
CB Macdonald, D Nedrud, PR Grimes, D Trinidad, JS Fraser, ...
bioRxiv, 2022.07. 26.501589, 2022
42022
The full spectrum of OCT1 (SLC22A1) mutations bridges transporter biophysics to drug pharmacogenomics
SW Yee, C Macdonald, D Mitrovic, X Zhou, ML Koleske, J Yang, DB Silva, ...
bioRxiv, 2023
32023
Rosace: a robust deep mutational scanning analysis framework employing position and mean-variance shrinkage
J Rao, R Xin, C Macdonald, M Howard, GO Estevam, SW Yee, M Wang, ...
bioRxiv, 2023.10. 24.562292, 2023
22023
DIMPLE library generation and assembly protocol
C Macdonald, D Nedrud, PR Grimes, D Trinidad, C Shin, J Fraser, ...
12023
Molecular basis of proton-sensing by G protein-coupled receptors
MK Howard, N Hoppe, XP Huang, CB Macdonald, E Mehrotra, PR Grimes, ...
bioRxiv, 2024
2024
Studying protein variation in evolution, disease, and biology through deep insertion, deletion, and missense mutational scanning
CB Macdonald
Biophysical Journal 122 (3), 519a, 2023
2023
Substrate Recognition of the Small Multidrug Resistance (SMR) Family
OE Burata, CB Macdonald, AA Kermani, R Stockbridge
Biophysical Journal 120 (3), 212a, 2021
2021
Evolution of Inverted Repeats in Membrane Transporters
CB Macdonald, T Cao, R Stockbridge
Biophysical Journal 120 (3), 59a, 2021
2021
Biophysical Characterization and Structural Studies of Small Multidrug Resistance Family of Transporters
AA Kermani, CB Macdonald, R Stockbridge
Biophysical Journal 120 (3), 70a, 2021
2021
Overlapping Substrate Specificities in the Small Multidrug Resistance (SMR) Family of Transporters
CB Macdonald, AA Kermani, RB Stockbridge
Biophysical Journal 118 (3), 130a, 2020
2020
Substrate Recognition of Guanidinium Exporters (Gdx) from the Small Multidrug Resistance (SMR) Family
OE Burata, CB Macdonald, AA Kermani, R Stockbridge
Biophysical Journal 118 (3), 130a, 2020
2020
Phylogenetic and Sequence Analysis of the Flucs, a Remarkable Family of Fluoride Channels
CB Macdonald, RB Stockbridge
Biophysical Journal 112 (3), 255a, 2017
2017
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Articles 1–20