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Steve Lu
Steve Lu
MD/PhD Student, Johns Hopkins University School of Medicine
Verified email at jhmi.edu
Title
Cited by
Cited by
Year
Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
DT Le, JN Durham, KN Smith, H Wang, BR Bartlett, LK Aulakh, S Lu, ...
Science 357 (6349), 409-413, 2017
60062017
Comparison of biomarker modalities for predicting response to PD-1/PD-L1 checkpoint blockade: a systematic review and meta-analysis
S Lu, JE Stein, DL Rimm, DW Wang, JM Bell, DB Johnson, JA Sosman, ...
JAMA oncology 5 (8), 1195-1204, 2019
5152019
DNA sensing in mismatch repair-deficient tumor cells is essential for anti-tumor immunity
C Lu, J Guan, S Lu, Q Jin, B Rousseau, T Lu, D Stephens, H Zhang, J Zhu, ...
Cancer cell 39 (1), 96-108. e6, 2021
1772021
The spectrum of benefit from checkpoint blockade in hypermutated tumors
B Rousseau, MB Foote, SB Maron, BH Diplas, S Lu, G Argilés, A Cercek, ...
New England Journal of Medicine 384 (12), 1168-1170, 2021
1572021
Noninvasive detection of microsatellite instability and high tumor mutation burden in cancer patients treated with PD-1 blockade
A Georgiadis, JN Durham, LA Keefer, BR Bartlett, M Zielonka, D Murphy, ...
Clinical Cancer Research 25 (23), 7024-7034, 2019
1212019
Short inverted repeats are hotspots for genetic instability: relevance to cancer genomes
S Lu, G Wang, A Bacolla, J Zhao, S Spitser, KM Vasquez
Cell reports 10 (10), 1674-1680, 2015
1162015
LBA1 CheckMate 77T: Phase III study comparing neoadjuvant nivolumab (NIVO) plus chemotherapy (chemo) vs neoadjuvant placebo plus chemo followed by surgery and adjuvant NIVO or …
T Cascone, MM Awad, JD Spicer, J He, S Lu, B Sepesi, F Tanaka, ...
Annals of Oncology 34, S1295, 2023
452023
CD4 T cell–dependent rejection of beta-2 microglobulin null mismatch repair–deficient tumors
G Germano, S Lu, G Rospo, S Lamba, B Rousseau, S Fanelli, D Stenech, ...
Cancer discovery 11 (7), 1844-1859, 2021
442021
The origin of highly elevated cell-free DNA in healthy individuals and patients with pancreatic, colorectal, lung, or ovarian cancer
AK Mattox, C Douville, Y Wang, M Popoli, J Ptak, N Silliman, L Dobbyn, ...
Cancer discovery 13 (10), 2166-2179, 2023
142023
Different Biomarker Modalities and Response to Anti–PD-1/PD-L1 Therapies—Reply
S Lu, H Wang, JM Taube
JAMA oncology 6 (2), 299-299, 2020
32020
Tumor genomic alterations in severe-combined immunodeficiency bare-lymphocyte syndrome genes are associated with high mutational burden and disproportional neo-antigen rates
Y Wang, DB Johnson, S Lu, LA Diaz, Y Xu, JM Balko
Journal for ImmunoTherapy of Cancer 7, 1-8, 2019
22019
Cruciform DNA structure formed at short inverted repeats: A source of genetic instability in vivo
PP Mandke, P Kompella, S Lu, G Wang, K Vasquez
The FASEB Journal 33 (S1), 457.9-457.9, 2019
22019
Whole-Slide Imaging, Mutual Information Registration for Multiplex Immunohistochemistry and Immunofluorescence
J Doyle, BF Green, M Eminizer, D Jimenez-Sanchez, S Lu, EL Engle, ...
Laboratory Investigation 103 (8), 100175, 2023
2023
The rapid and highly parallel identification of antibodies with defined biological activities by SLISY
S Lu, AK Mattox, P Aitana Azurmendi, I Christodoulou, KM Wright, ...
Nature communications 14 (1), 17, 2023
2023
Cruciform DNA Formed at Short Inverted Repeats: A Source of Genetic Instability In Vivo.
P Mandke, P Kompella, S Lu, G Wang, K Vasquez
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 62, 43-44, 2021
2021
Exploring the Mechanisms of Cruciform DNA-induced Genetic Instability in Eukaryotic Systems.
P Mandke, P Kompella, S Lu, J Zhao, G Wang, KM Vasquez
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 61, 57-58, 2020
2020
906 Early effector T-cell densities predict response in patients with advanced Merkel cell carcinoma treated with anti-PD-1
S Lu, F Succaria, B Green, N Giraldo-Castillo, J Taube
Journal of Investigative Dermatology 140 (7), S119, 2020
2020
823 Biomarker approaches for anti-PD-1 in melanoma: A meta-analysis
S Lu, J Stein, L Danilova, C Hoyt, J Taube
Journal of Investigative Dermatology 139 (5), S142, 2019
2019
Replication-Dependent and Replication-Independent Models of DNA Structure-Induced Genetic Instability.
S Lu, G Wang, A Bacolla, J Zhao, S Spitser, KM Vasquez
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 56, S47-S47, 2015
2015
Short inverted repeats are hot spots for genetic instability in mammalian cells
S Lu
2012
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