Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade DT Le, JN Durham, KN Smith, H Wang, BR Bartlett, LK Aulakh, S Lu, ... Science 357 (6349), 409-413, 2017 | 6006 | 2017 |
Comparison of biomarker modalities for predicting response to PD-1/PD-L1 checkpoint blockade: a systematic review and meta-analysis S Lu, JE Stein, DL Rimm, DW Wang, JM Bell, DB Johnson, JA Sosman, ... JAMA oncology 5 (8), 1195-1204, 2019 | 515 | 2019 |
DNA sensing in mismatch repair-deficient tumor cells is essential for anti-tumor immunity C Lu, J Guan, S Lu, Q Jin, B Rousseau, T Lu, D Stephens, H Zhang, J Zhu, ... Cancer cell 39 (1), 96-108. e6, 2021 | 177 | 2021 |
The spectrum of benefit from checkpoint blockade in hypermutated tumors B Rousseau, MB Foote, SB Maron, BH Diplas, S Lu, G Argilés, A Cercek, ... New England Journal of Medicine 384 (12), 1168-1170, 2021 | 157 | 2021 |
Noninvasive detection of microsatellite instability and high tumor mutation burden in cancer patients treated with PD-1 blockade A Georgiadis, JN Durham, LA Keefer, BR Bartlett, M Zielonka, D Murphy, ... Clinical Cancer Research 25 (23), 7024-7034, 2019 | 121 | 2019 |
Short inverted repeats are hotspots for genetic instability: relevance to cancer genomes S Lu, G Wang, A Bacolla, J Zhao, S Spitser, KM Vasquez Cell reports 10 (10), 1674-1680, 2015 | 116 | 2015 |
LBA1 CheckMate 77T: Phase III study comparing neoadjuvant nivolumab (NIVO) plus chemotherapy (chemo) vs neoadjuvant placebo plus chemo followed by surgery and adjuvant NIVO or … T Cascone, MM Awad, JD Spicer, J He, S Lu, B Sepesi, F Tanaka, ... Annals of Oncology 34, S1295, 2023 | 45 | 2023 |
CD4 T cell–dependent rejection of beta-2 microglobulin null mismatch repair–deficient tumors G Germano, S Lu, G Rospo, S Lamba, B Rousseau, S Fanelli, D Stenech, ... Cancer discovery 11 (7), 1844-1859, 2021 | 44 | 2021 |
The origin of highly elevated cell-free DNA in healthy individuals and patients with pancreatic, colorectal, lung, or ovarian cancer AK Mattox, C Douville, Y Wang, M Popoli, J Ptak, N Silliman, L Dobbyn, ... Cancer discovery 13 (10), 2166-2179, 2023 | 14 | 2023 |
Different Biomarker Modalities and Response to Anti–PD-1/PD-L1 Therapies—Reply S Lu, H Wang, JM Taube JAMA oncology 6 (2), 299-299, 2020 | 3 | 2020 |
Tumor genomic alterations in severe-combined immunodeficiency bare-lymphocyte syndrome genes are associated with high mutational burden and disproportional neo-antigen rates Y Wang, DB Johnson, S Lu, LA Diaz, Y Xu, JM Balko Journal for ImmunoTherapy of Cancer 7, 1-8, 2019 | 2 | 2019 |
Cruciform DNA structure formed at short inverted repeats: A source of genetic instability in vivo PP Mandke, P Kompella, S Lu, G Wang, K Vasquez The FASEB Journal 33 (S1), 457.9-457.9, 2019 | 2 | 2019 |
Whole-Slide Imaging, Mutual Information Registration for Multiplex Immunohistochemistry and Immunofluorescence J Doyle, BF Green, M Eminizer, D Jimenez-Sanchez, S Lu, EL Engle, ... Laboratory Investigation 103 (8), 100175, 2023 | | 2023 |
The rapid and highly parallel identification of antibodies with defined biological activities by SLISY S Lu, AK Mattox, P Aitana Azurmendi, I Christodoulou, KM Wright, ... Nature communications 14 (1), 17, 2023 | | 2023 |
Cruciform DNA Formed at Short Inverted Repeats: A Source of Genetic Instability In Vivo. P Mandke, P Kompella, S Lu, G Wang, K Vasquez ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 62, 43-44, 2021 | | 2021 |
Exploring the Mechanisms of Cruciform DNA-induced Genetic Instability in Eukaryotic Systems. P Mandke, P Kompella, S Lu, J Zhao, G Wang, KM Vasquez ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 61, 57-58, 2020 | | 2020 |
906 Early effector T-cell densities predict response in patients with advanced Merkel cell carcinoma treated with anti-PD-1 S Lu, F Succaria, B Green, N Giraldo-Castillo, J Taube Journal of Investigative Dermatology 140 (7), S119, 2020 | | 2020 |
823 Biomarker approaches for anti-PD-1 in melanoma: A meta-analysis S Lu, J Stein, L Danilova, C Hoyt, J Taube Journal of Investigative Dermatology 139 (5), S142, 2019 | | 2019 |
Replication-Dependent and Replication-Independent Models of DNA Structure-Induced Genetic Instability. S Lu, G Wang, A Bacolla, J Zhao, S Spitser, KM Vasquez ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 56, S47-S47, 2015 | | 2015 |
Short inverted repeats are hot spots for genetic instability in mammalian cells S Lu | | 2012 |