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Poorva Sandlesh
Poorva Sandlesh
Postdoctoral Fellow
Verified email at pennmedicine.upenn.edu
Title
Cited by
Cited by
Year
Structure and function of the histone chaperone FACT–Resolving FACTual issues
K Gurova, HW Chang, ME Valieva, P Sandlesh, VM Studitsky
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1861 (9), 892-904, 2018
982018
Pharmacological targeting of the histone chaperone complex FACT preferentially eliminates glioblastoma stem cells and prolongs survival in preclinical models
JKT Dermawan, M Hitomi, DJ Silver, Q Wu, P Sandlesh, AE Sloan, ...
Cancer research 76 (8), 2432-2442, 2016
722016
TRAIN (Transcription of Repeats Activates INterferon) in response to chromatin destabilization induced by small molecules in mammalian cells
K Leonova, A Safina, E Nesher, P Sandlesh, R Pratt, C Burkhart, ...
Elife 7, e30842, 2018
422018
TIGIT and PD-1 immune checkpoint pathways are associated with patient outcome and anti-tumor immunity in glioblastoma
I Raphael, R Kumar, LH McCarl, K Shoger, L Wang, P Sandlesh, ...
Frontiers in immunology 12, 637146, 2021
402021
Uncovering the fine print of the CreERT2-LoxP system while generating a conditional knockout mouse model of Ssrp1 gene
P Sandlesh, T Juang, A Safina, MJ Higgins, KV Gurova
PLoS One 13 (6), e0199785, 2018
332018
Characterization of systemic immunosuppression by IDH mutant glioma small extracellular vesicles
N Ludwig, A Rao, P Sandlesh, SS Yerneni, AD Swain, KM Bullock, ...
Neuro-oncology 24 (2), 197-209, 2022
252022
Epigenomic tensor predicts disease subtypes and reveals constrained tumor evolution
JR Leistico, P Saini, CR Futtner, M Hejna, Y Omura, PN Soni, P Sandlesh, ...
Cell reports 34 (13), 2021
132021
Prevention of chromatin destabilization by FACT is crucial for malignant transformation
P Sandlesh, A Safina, I Goswami, L Prendergast, S Rosario, EC Gomez, ...
Iscience 23 (6), 2020
132020
Machine learning identification of immunotherapy targets in low-grade glioma using RNA sequencing expression data
P Agarwal, OM Beale, X Zhang, P Sandlesh, E Jaman, N Amankulor
World Neurosurgery 163, e349-e362, 2022
62022
FACT maintains nucleosomes during transcription and stem cell viability in adult mice
I Goswami, P Sandlesh, A Stablewski, I Toshkov, AF Safina, M Magnitov, ...
EMBO reports 23 (4), e53684, 2022
62022
History of atopy confers improved outcomes in IDH mutant and wildtype lower grade gliomas
E Jaman, X Zhang, P Sandlesh, A Habib, J Allen, RG Saraiya, ...
Journal of Neuro-Oncology 155, 133-141, 2021
42021
In vivo efficacy of decitabine as a natural killer cell–mediated immunotherapy against isocitrate dehydrogenase mutant gliomas
X Zhang, WJ Kim, AV Rao, E Jaman, CP Deibert, P Sandlesh, K Krueger, ...
Neurosurgical Focus 52 (2), E3, 2022
32022
FACT-mediated maintenance of chromatin integrity during transcription is essential for viability of mammalian stem cells
I Goswami
State University of New York at Buffalo, 2021
12021
All-trans retinoic acid induces durable tumor immunity in IDH-mutant gliomas by rescuing transcriptional repression of the CRBP1-retinoic acid axis
A Rao, X Zhang, A Cillo, JH Sussman, P Sandlesh, AC Tarbay, ...
bioRxiv, 2024.04. 09.588752, 2024
2024
FACT-mediated maintenance of chromatin integrity during transcription is essential for mammalian stem cell viability
I Goswami, P Sandlesh, A Stablewski, I Toshkov, AF Safina, M Magnitov, ...
bioRxiv, 2021.06. 21.449309, 2021
2021
Understanding the role of histone chaperone FACT in mammalian cells using a conditional FACT knockout mouse model
I Goswami, P Sandlesh, A Safina, K Gurova
TRANSGENIC RESEARCH 29 (SUPPL 1), 14-14, 2020
2020
Induction of nucleosome disassembly with small molecules as a novel anti-cancer approach
A Safina, P Sandlesh, J Wang, KV Gurova
Cancer Research 80 (16_Supplement), 1747-1747, 2020
2020
Conditional knockout of histone chaperone FACT in mice: Consequences for normal tissues
MA Ito, P Sandlesh, I Goswami, LA Prendergast, K Gurova
Cancer Research 79 (13_Supplement), 5193-5193, 2019
2019
Generation of a Conditional Knockout of FACT Subunit SSRP1 Mouse Model to Study the Consequences of FACT Inactivation
P Sandlesh
State University of New York at Buffalo, 2018
2018
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Articles 1–19