The activin A‐follistatin system: potent regulator of human extracellular matrix mineralization M Eijken, S Swagemakers, M Koedam, C Steenbergen, P Derkx, ... The FASEB Journal 21 (11), 2949-2960, 2007 | 235 | 2007 |
The essential role of glucocorticoids for proper human osteoblast differentiation and matrix mineralization M Eijken, M Koedam, M van Driel, CJ Buurman, HAP Pols, ... Molecular and cellular endocrinology 248 (1-2), 87-93, 2006 | 169 | 2006 |
Susceptibility of human mesenchymal stem cells to tacrolimus, mycophenolic acid, and rapamycin MJ Hoogduijn, MJ Crop, SS Korevaar, AMA Peeters, M Eijken, ... Transplantation 86 (9), 1283-1291, 2008 | 130 | 2008 |
11β-Hydroxysteroid dehydrogenase expression and glucocorticoid synthesis are directed by a molecular switch during osteoblast differentiation M Eijken, M Hewison, MS Cooper, FH de Jong, H Chiba, PM Stewart, ... Molecular Endocrinology 19 (3), 621-631, 2005 | 121 | 2005 |
11β-Hydroxysteroid dehydrogenase expression and glucocorticoid synthesis are directed by a molecular switch during osteoblast differentiation M Eijken, M Hewison, MS Cooper, FH de Jong, H Chiba, PM Stewart, ... Molecular Endocrinology 19 (3), 621-631, 2005 | 121 | 2005 |
Wnt signaling acts and is regulated in a human osteoblast differentiation dependent manner M Eijken, IMJ Meijer, I Westbroek, M Koedam, H Chiba, AG Uitterlinden, ... Journal of cellular biochemistry 104 (2), 568-579, 2008 | 110 | 2008 |
Calcifying vascular smooth muscle cells and osteoblasts: independent cell types exhibiting extracellular matrix and biomineralization-related mimicries RDAM Alves, M Eijken, J van de Peppel, JPTM van Leeuwen BMC genomics 15, 1-14, 2014 | 105 | 2014 |
Systems biology towards life in silico: mathematics of the control of living cells HV Westerhoff, A Kolodkin, R Conradie, SJ Wilkinson, FJ Bruggeman, ... Journal of mathematical biology 58, 7-34, 2009 | 104 | 2009 |
1α,25‐(OH)2D3 acts in the early phase of osteoblast differentiation to enhance mineralization via accelerated production of mature matrix vesicles VJ Woeckel, R Alves, SMA Swagemakers, M Eijken, H Chiba, ... Journal of cellular physiology 225 (2), 593-600, 2010 | 100 | 2010 |
A new concept underlying stem cell lineage skewing that explains the detrimental effects of thiazolidinediones on bone C Bruedigam, M Eijken, M Koedam, J Van De Peppel, K Drabek, H Chiba, ... Stem cells 28 (5), 916-927, 2010 | 97 | 2010 |
Connectivity Map-based discovery of parbendazole reveals targetable human osteogenic pathway AM Brum, J van de Peppel, CS Van Der Leije, M Schreuders-Koedam, ... Proceedings of the National Academy of Sciences 112 (41), 12711-12716, 2015 | 93 | 2015 |
Synergistic induction of local glucocorticoid generation by inflammatory cytokines and glucocorticoids: implications for inflammation associated bone loss K Kaur, R Hardy, MM Ahasan, M Eijken, JP Van Leeuwen, A Filer, ... Annals of the rheumatic diseases 69 (6), 1185-1190, 2010 | 91 | 2010 |
Infusing mesenchymal stromal cells into porcine kidneys during normothermic machine perfusion: intact MSCs can be traced and localised to glomeruli M Pool, T Eertman, J Sierra Parraga, N ’t Hart, M Roemeling-van Rhijn, ... International journal of molecular sciences 20 (14), 3607, 2019 | 64 | 2019 |
Activin A suppresses osteoblast mineralization capacity by altering extracellular matrix (ECM) composition and impairing matrix vesicle (MV) production RDAM Alves, M Eijken, K Bezstarosti, JAA Demmers, JPTM van Leeuwen Molecular & Cellular Proteomics 12 (10), 2890-2900, 2013 | 64 | 2013 |
Basic techniques in human mesenchymal stem cell cultures: differentiation into osteogenic and adipogenic lineages, genetic perturbations, and phenotypic analyses C Bruedigam, M Driel, M Koedam, J Peppel, BCJ van der Eerden, ... Current protocols in stem cell biology 17 (1), 1H. 3.1-1H. 3.20, 2011 | 63 | 2011 |
GPM6B regulates osteoblast function and induction of mineralization by controlling cytoskeleton and matrix vesicle release K Drabek, J van de Peppel, M Eijken, JPTM van Leeuwen Journal of Bone and Mineral Research 26 (9), 2045-2051, 2011 | 61 | 2011 |
Stretch‐induced inhibition of Wnt/β‐catenin signaling in mineralizing osteoblasts JHW Jansen, M Eijken, H Jahr, H Chiba, JAN Verhaar, ... Journal of Orthopaedic Research 28 (3), 390-396, 2010 | 56 | 2010 |
Unraveling the human bone microenvironment beyond the classical extracellular matrix proteins: a human bone protein library RDAM Alves, JAA Demmers, K Bezstarosti, BCJ van der Eerden, ... Journal of proteome research 10 (10), 4725-4733, 2011 | 46 | 2011 |
Donor-derived mesenchymal stem cells remain present and functional in the transplanted human heart MJ Hoogduijn, MJ Crop, AMA Peeters, SS Korevaar, M Eijken, ... American Journal of Transplantation 9 (1), 222-230, 2009 | 46 | 2009 |
Mesenchymal stromal cells as anti-inflammatory and regenerative mediators for donor kidneys during normothermic machine perfusion JM Sierra-Parraga, M Eijken, J Hunter, C Moers, H Leuvenink, B Møller, ... Stem cells and development 26 (16), 1162-1170, 2017 | 44 | 2017 |