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Nuno Santos Leal
Nuno Santos Leal
University of Cambridge, MRC Toxicology Unit
Verified email at cam.ac.uk
Title
Cited by
Cited by
Year
Links between air pollution and COVID-19 in England
M Travaglio, Y Yu, R Popovic, L Selley, NS Leal, LM Martins
Environmental pollution 268, 115859, 2021
6632021
Mitofusin‐2 knockdown increases ER–mitochondria contact and decreases amyloid β‐peptide production
NS Leal, B Schreiner, CM Pinho, R Filadi, B Wiehager, H Karlström, ...
Journal of cellular and molecular medicine 20 (9), 1686-1695, 2016
1592016
TOM70 Sustains Cell Bioenergetics by Promoting IP3R3-Mediated ER to Mitochondria Ca2+ Transfer
R Filadi, NS Leal, B Schreiner, A Rossi, G Dentoni, CM Pinho, ...
Current Biology 28 (3), 369-382. e6, 2018
1322018
Alzheimer’s and Parkinson’s diseases predict different COVID-19 outcomes: a UK Biobank study
Y Yu, M Travaglio, R Popovic, NS Leal, LM Martins
Geriatrics 6 (1), 10, 2021
682021
Amyloid Β-peptide increases mitochondria-endoplasmic reticulum contact altering mitochondrial function and autophagosome formation in Alzheimer’s disease-related models
NS Leal, G Dentoni, B Schreiner, L Naia, A Piras, C Graff, A Cattaneo, ...
Cells 9 (12), 2552, 2020
432020
Mind the gap: Mitochondria and the endoplasmic reticulum in neurodegenerative diseases
NS Leal, LM Martins
Biomedicines 9 (2), 227, 2021
302021
Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling
L Naia, CM Pinho, G Dentoni, J Liu, NS Leal, DMS Ferreira, B Schreiner, ...
BMC biology 19, 1-21, 2021
282021
Alterations in mitochondria-endoplasmic reticulum connectivity in human brain biopsies from idiopathic normal pressure hydrocephalus patients
NS Leal, G Dentoni, B Schreiner, OP Kämäräinen, N Partanen, ...
Acta neuropathologica communications 6 (1), 102, 2018
252018
Paracetamol is associated with a lower risk of COVID-19 infection and decreased ACE2 protein expression: a retrospective analysis
NS Leal, Y Yu, Y Chen, G Fedele, LM Martins
Covid 1 (1), 218-229, 2021
172021
Suppression of intestinal dysfunction in a Drosophila model of Parkinson’s disease is neuroprotective
G Fedele, SHY Loh, I Celardo, NS Leal, S Lehmann, AC Costa, ...
Nature Aging 2 (4), 317-331, 2022
92022
Mitochondrial hypermetabolism precedes impaired autophagy and synaptic disorganization in App knock-in Alzheimer mouse models
L Naia, M Shimozawa, E Bereczki, X Li, J Liu, R Jiang, R Giraud, NS Leal, ...
Molecular psychiatry 28 (9), 3966-3981, 2023
82023
Upregulation of Tribbles decreases body weight and increases sleep duration
R Popovic, Y Yu, NS Leal, G Fedele, SHY Loh, LM Martins
Disease Models & Mechanisms 16 (4), dmm049942, 2023
52023
Blocking dPerk in the intestine suppresses neurodegeneration in a Drosophila model of Parkinson’s disease
R Popovic, A Mukherjee, NS Leal, L Morris, Y Yu, SHY Loh, ...
Cell Death & Disease 14 (3), 206, 2023
52023
Mitochondrial Alterations in Neurons Derived from the Murine App NL-F Knock-In Model of Alzheimer’s Disease
G Dentoni, L Naia, B Portal, NS Leal, P Nilsson, M Lindskog, ...
Journal of Alzheimer's Disease 90 (2), 565-583, 2022
32022
Blocking toxicity from the gut is neuroprotective in a Parkinson’s disease model
R Popovic, A Mukherjee, NS Leal, L Morris, Y Yu, SHY Loh, LM Martins
2023
Early mitochondrial dysfunction proceeds neuroinflammation, synaptic alteration, and autophagy impairment in hippocampus of App knock-in Alzheimer mouse models
L Naia, M Shimozawa, E Bereczki, X Li, J Liu, R Jiang, NS Leal, CM Pinho, ...
bioRxiv, 2023.03. 07.531542, 2023
2023
The interplay between mitochondria-endoplasmic reticulum contacts and Alzheimer’s disease
NJ Santos Leal
Inst för neurobiologi, vårdvetenskap och samhälle/Dept of Neurobiology, Care …, 2019
2019
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