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Donald Bottaro
Donald Bottaro
National Cancer Institute
Verified email at helix.nih.gov - Homepage
Title
Cited by
Cited by
Year
Identification of the Hepatocyte Growth Factor Receptor As the c-met Proto-Oncogene Product
DP Bottaro, JS Rubin, DL Faletto, AML Chan, TE Kmiecik, ...
Science 251 (4995), 802-804, 1991
29911991
Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma
TCGAR Network
The New England Journal of Medicine 374, 135-145, 2016
11762016
Activation of RET as a Dominant Transforming Gene by Germline Mutations of MEN2A and MEN2B
M Santoro, F Carlomagno, A Romano, DP Bottaro, NA Dathan, M Grieco, ...
Science 267 (5196), 381-383, 1995
10061995
Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene.
T Miki, DP Bottaro, TP Fleming, CL Smith, WH Burgess, AM Chan, ...
Proceedings of the National Academy of Sciences 89 (1), 246-250, 1992
9661992
The cancer genome atlas comprehensive molecular characterization of renal cell carcinoma
CJ Ricketts, AA De Cubas, H Fan, CC Smith, M Lang, E Reznik, R Bowlby, ...
Cell reports 23 (1), 313-326. e5, 2018
8172018
A broad-spectrum human lung fibroblast-derived mitogen is a variant of hepatocyte growth factor.
JS Rubin, AML Chan, DP Bottaro, WH Burgess, WG Taylor, AC Cech, ...
Proceedings of the National Academy of Sciences 88 (2), 415-419, 1991
6421991
Targeting the c-Met signaling pathway in cancer
B Peruzzi, DP Bottaro
Clinical cancer research 12 (12), 3657-3660, 2006
5502006
PDGF induction of tyrosine phosphorylation of GTPase activating protein
CJ Molloy, DP Bottaro, TP Fleming, MS Marshall, JB Gibbs, SA Aaronson
Nature 342 (6250), 711-714, 1989
5501989
Expression cDNA cloning of the KGF receptor by creation of a transforming autocrine loop
T Miki, TP Fleming, DP Bottaro, JS Rubin, D Ron, SA Aaronson
Science 251 (4989), 72-75, 1991
5401991
Secreted frizzled-related protein-1 binds directly to Wingless and is a biphasic modulator of Wnt signaling
A Uren, F Reichsman, V Anest, WG Taylor, K Muraiso, DP Bottaro, ...
Journal of Biological Chemistry 275 (6), 4374-4382, 2000
5022000
Phase II and biomarker study of the dual MET/VEGFR2 inhibitor foretinib in patients with papillary renal cell carcinoma
TK Choueiri, U Vaishampayan, JE Rosenberg, TF Logan, AL Harzstark, ...
Journal of Clinical Oncology 31 (2), 181, 2013
4812013
Keratinocyte growth factor
JS Rubin, DP Bottaro, M Chedid, T Miki, D Ron, HG Cheon, WG Taylor, ...
Cell biology international 19 (5), 399-412, 1995
3991995
Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling
P Fedi, A Bafico, AN Soria, WH Burgess, T Miki, DP Bottaro, MH Kraus, ...
Journal of biological Chemistry 274 (27), 19465-19472, 1999
3821999
Hepatocyte growth factor/scatter factor and its receptor, the c-met proto-oncogene product
JS Rubin, DP Bottaro, SA Aaronson
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1155 (3), 357-371, 1993
3711993
Smad2 transduces common signals from receptor serine–threonine and tyrosine kinases
MP De Caestecker, WT Parks, CJ Frank, P Castagnino, DP Bottaro, ...
Genes & development 12 (11), 1587-1592, 1998
3661998
Multilevel genomics-based taxonomy of renal cell carcinoma
F Chen, Y Zhang, Y Şenbabaoğlu, G Ciriello, L Yang, E Reznik, B Shuch, ...
Cell reports 14 (10), 2476-2489, 2016
3402016
c-Met autocrine activation induces development of malignant melanoma and acquisition of the metastatic phenotype
T Otsuka, H Takayama, R Sharp, G Celli, WJ LaRochelle, DP Bottaro, ...
Cancer research 58 (22), 5157-5167, 1998
3301998
Genetic basis of cancer of the kidney: disease-specific approaches to therapy
WM Linehan, J Vasselli, R Srinivasan, MCM Walther, M Merino, P Choyke, ...
Clinical Cancer Research 10 (18), 6282S-6289S, 2004
2972004
Identification of a competitive HGF antagonist encoded by an alternative transcript
AML Chan, JS Rubin, DP Bottaro, DW Hirschfield, M Chedid, ...
Science 254 (5036), 1382-1385, 1991
2871991
Molecular genetics and cellular features of TFE3 and TFEB fusion kidney cancers
EC Kauffman, CJ Ricketts, S Rais-Bahrami, Y Yang, MJ Merino, ...
Nature Reviews Urology 11 (8), 465-475, 2014
2812014
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