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Wenbing Chen
Wenbing Chen
Verified email at uwm.edu
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Year
Highly Enantioselective Construction of Spiro[4H-pyran-3,3′-oxindoles] Through a Domino Knoevenagel/Michael/Cyclization Sequence Catalyzed by Cupreine
WB Chen, ZJ Wu, QL Pei, LF Cun, XM Zhang, WC Yuan
Organic letters 12 (14), 3132-3135, 2010
3242010
Organocatalytic direct asymmetric aldol reactions of 3-isothiocyanato oxindoles to ketones: stereocontrolled synthesis of spirooxindoles bearing highly congested contiguous …
WB Chen, ZJ Wu, J Hu, LF Cun, XM Zhang, WC Yuan
Organic Letters 13 (9), 2472-2475, 2011
1992011
Organocatalytic Asymmetric Michael Addition of Pyrazolin‐5‐ones to Nitroolefins with Bifunctional Thiourea: Stereocontrolled Construction of Contiguous Quaternary and Tertiary …
YH Liao, WB Chen, ZJ Wu, XL Du, LF Cun, XM Zhang, WC Yuan
Advanced Synthesis & Catalysis 352 (5), 827-832, 2010
1462010
Highly enantioselective aldol reaction of acetaldehyde and isatins only with 4-hydroxydiarylprolinol as catalyst: Concise stereoselective synthesis of (R)-convolutamydines B …
WB Chen, XL Du, LF Cun, XM Zhang, WC Yuan
Tetrahedron 66 (7), 1441-1446, 2010
1212010
Highly Efficient and Stereoselective Construction of Dispiro-[oxazolidine-2-thione] bisoxindoles and Dispiro [imidazolidine-2-thione] bisoxindoles
YY Han, WB Chen, WY Han, ZJ Wu, XM Zhang, WC Yuan
Organic letters 14 (2), 490-493, 2012
1202012
Highly enantioselective synthesis of β‐amino acid derivatives by the Lewis base catalyzed hydrosilylation of β‐enamino esters
HJ Zheng, WB Chen, ZJ Wu, JG Deng, WQ Lin, WC Yuan, XM Zhang
Chemistry–A European Journal 14 (32), 9864-9867, 2008
1182008
Reactive oxygen species (ROS) inducible DNA cross-linking agents and their effect on cancer cells and normal lymphocytes
W Chen, K Balakrishnan, Y Kuang, Y Han, M Fu, V Gandhi, X Peng
Journal of medicinal chemistry 57 (11), 4498-4510, 2014
1092014
Diastereo- and Enantioselective Conjugate Addition of 3-Substituted Oxindoles to Nitroolefins Catalyzed by a Chiral Ni(OAc)2-Diamine Complex under Mild …
YY Han, ZJ Wu, WB Chen, XL Du, XM Zhang, WC Yuan
Organic Letters 13 (19), 5064-5067, 2011
812011
Catalyst-free aldol condensation of ketones and isatins under mild reaction conditions in DMF with molecular sieves 4 Ć as additive
WB Chen, YH Liao, XL Du, XM Zhang, WC Yuan
Green Chemistry 11 (9), 1465-1476, 2009
562009
Discovery and optimization of novel hydrogen peroxide activated aromatic nitrogen mustard derivatives as highly potent anticancer agents
W Chen, H Fan, K Balakrishnan, Y Wang, H Sun, Y Fan, V Gandhi, ...
Journal of Medicinal Chemistry 61 (20), 9132-9145, 2018
422018
Highly efficient synthesis of spiro [oxazolidine-2-thione-oxindoles] with 3-isothiocyanato oxindoles and aldehydes via an organocatalytic cascade aldol-cyclization reaction
WB Chen, WY Han, YY Han, XM Zhang, WC Yuan
Tetrahedron 69 (26), 5281-5286, 2013
382013
Aromatic Nitrogen Mustard‐Based Prodrugs: Activity, Selectivity, and the Mechanism of DNA Cross‐Linking
W Chen, Y Han, X Peng
Chemistry–A European Journal 20 (24), 7410-7418, 2014
322014
Hydrogen peroxide activated quinone methide precursors with enhanced DNA cross-linking capability and cytotoxicity towards cancer cells
Y Wang, H Fan, K Balakrishnan, Z Lin, S Cao, W Chen, Y Fan, QA Guthrie, ...
European journal of medicinal chemistry 133, 197-207, 2017
312017
UV-induced DNA interstrand cross-linking and direct strand breaks from a new type of binitroimidazole analogue
Y Han, W Chen, Y Kuang, H Sun, Z Wang, X Peng
Chemical research in toxicology 28 (5), 919-926, 2015
152015
Assessment of Phenylboronic Acid Nitrogen Mustards as Potent and Selective Drug Candidates for Triple-Negative Breast Cancer
H Fan, MAU Zaman, W Chen, T Ali, A Campbell, Q Zhang, NI Setu, ...
ACS Pharmacology & Translational Science 4 (2), 687-702, 2021
82021
Anti-cancer agents
X Peng, Y Kuang, CAO Sheng, W Chen, Y Wang
US Patent 8,637,490, 2014
32014
Anti-cancer agents
X Peng, Y Kuang, CAO Sheng, W Chen, Y Wang
US Patent 8,962,670, 2015
2015
Synthesis of Isatin Derivatives
Y LIAO, W CHEN, X ZHANG, W YUAN
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